sodium-bromide and Meningitis

Bromide partition ratio was determined in 32 cases of tuberculous meningitis, 6 pyogenic meningitis, 8 viral meningitis and 9 cases of febrile convulsions. Bromide partition ratio below the critical value of 1.6 was present in 30 out of 32 tuberculous meningitis patients (93.74%) whereas all the control children had a ratio above 1.6. Two children who were on regular chemotherapy showed progressively rising ratio. It is concluded that in doubtful cases with inconclusive CSF picture, a low bromide partition ratio is a strong reason for starting antituberculous treatment without any delay. A very low ratio also suggests poor prognosis.

Topics: Adolescent; Bromides; Child; Child, Preschool; Diagnosis, Differential; Humans; Infant; Meningitis; Seizures, Febrile; Sodium; Sodium Compounds; Tuberculosis, Meningeal