sodium-borohydride and Inflammation

sodium-borohydride has been researched along with Inflammation* in 2 studies

Other Studies

2 other study(ies) available for sodium-borohydride and Inflammation

Article	Year
Synthesis of 2-Organylchalcogenopheno[2,3-b]pyridines from Elemental Chalcogen and NaBH ChemMedChem, 2020, 09-16, Volume: 15, Issue:18 Topics: Analgesics; Animals; Antioxidants; Borohydrides; Chalcogens; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Inflammation; Male; Mice; Molecular Structure; Oxidation-Reduction; Pain; Polyethylene Glycols	2020
Improved pharmacological properties for superoxide dismutase modified with mannan. Biotechnology and applied biochemistry, 2006, Volume: 44, Issue:Pt 3 Mannan from Sacharomyces cerevisiae was activated by oxidation with NaIO(4) (sodium m-periodate) and further linked to SOD (superoxide dismutase) via reductive alkylation with NaBH(4) (sodium borohydride). The glycosidated enzyme contained an average of 1.2 mol of polysaccharide per mol of protein and retained 52% of its initial activity. The modified enzyme was 560-fold more resistant to inactivation with H(2)O(2) and acquired a lectin-recognition capacity in respect of concanavalin A. The anti-inflammatory activity of SOD was increased 2-fold and its plasma half-life time was prolonged from 4.8 min to 1.7 h after glycosylation with the polymer. Topics: Alkylation; Animals; Borohydrides; Carbohydrate Conformation; Carbohydrate Sequence; Carrageenan; Enzyme Activation; Glycosylation; Hydrogen Peroxide; Inflammation; Male; Mannans; Molecular Sequence Data; Oxidation-Reduction; Periodic Acid; Rats; Rats, Wistar; Saccharomyces cerevisiae; Structure-Activity Relationship; Superoxide Dismutase; Time Factors	2006

Article

Year

Synthesis of 2-Organylchalcogenopheno[2,3-b]pyridines from Elemental Chalcogen and NaBH

ChemMedChem, 2020, 09-16, Volume: 15, Issue:18

Topics: Analgesics; Animals; Antioxidants; Borohydrides; Chalcogens; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Inflammation; Male; Mice; Molecular Structure; Oxidation-Reduction; Pain; Polyethylene Glycols

2020

Improved pharmacological properties for superoxide dismutase modified with mannan.

Biotechnology and applied biochemistry, 2006, Volume: 44, Issue:Pt 3

Mannan from Sacharomyces cerevisiae was activated by oxidation with NaIO(4) (sodium m-periodate) and further linked to SOD (superoxide dismutase) via reductive alkylation with NaBH(4) (sodium borohydride). The glycosidated enzyme contained an average of 1.2 mol of polysaccharide per mol of protein and retained 52% of its initial activity. The modified enzyme was 560-fold more resistant to inactivation with H(2)O(2) and acquired a lectin-recognition capacity in respect of concanavalin A. The anti-inflammatory activity of SOD was increased 2-fold and its plasma half-life time was prolonged from 4.8 min to 1.7 h after glycosylation with the polymer.

Topics: Alkylation; Animals; Borohydrides; Carbohydrate Conformation; Carbohydrate Sequence; Carrageenan; Enzyme Activation; Glycosylation; Hydrogen Peroxide; Inflammation; Male; Mannans; Molecular Sequence Data; Oxidation-Reduction; Periodic Acid; Rats; Rats, Wistar; Saccharomyces cerevisiae; Structure-Activity Relationship; Superoxide Dismutase; Time Factors

2006