sodium-borohydride and Brain-Neoplasms

sodium-borohydride has been researched along with Brain-Neoplasms* in 1 studies

Trials

1 trial(s) available for sodium-borohydride and Brain-Neoplasms

Article	Year
Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Boron neutron capture therapy (BNCT) with Na2B12H11SH (BSH) or p-dihydroxyborylphenylalanine (BPA), and with a combination of both, was compared to radiotherapy with temozolomide, and the number of patients required to show statistically significant differences between the treatments was calculated. Whereas arms using BPA require excessive number of patients in each arm, a two-armed clinical trial with BSH and radiotherapy plus temozolomide is feasible. Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Germany; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Prevalence; Risk Factors; Survival Rate; Temozolomide; Treatment Outcome	2014

Article

Year

Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

Boron neutron capture therapy (BNCT) with Na2B12H11SH (BSH) or p-dihydroxyborylphenylalanine (BPA), and with a combination of both, was compared to radiotherapy with temozolomide, and the number of patients required to show statistically significant differences between the treatments was calculated. Whereas arms using BPA require excessive number of patients in each arm, a two-armed clinical trial with BSH and radiotherapy plus temozolomide is feasible.

Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Germany; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Prevalence; Risk Factors; Survival Rate; Temozolomide; Treatment Outcome

2014