sodium-bicarbonate and Rupture--Spontaneous

Spontaneous rupture of the stomach is an uncommon condition with a usually poor prognosis. The questions of pathophysiologic factors and the possible role of carbonated or bicarbonate-containing beverages were addressed.. A review of the literature based on a search of MEDLINE (1966-1998) was performed. Using the key word 'stomach rupture', we found 675 publications. 279 publications dealt with etiologic factors 15 of which mentioned the ingestion of bicarbonate preparations. No record of carbonated or bicarbonate-containing beverages as a single etiologic factor could be found.. These beverages do not seem to play a significant role in the pathogenesis of stomach rupture, whereas in rare cases bicarbonate preparations can cause rupture of the previously overdistended stomach.

Topics: Carbonated Beverages; Humans; Incidence; MEDLINE; Rupture, Spontaneous; Sodium Bicarbonate; Stomach Rupture

Topics: Colonoscopy; Drug Combinations; Esophageal Diseases; Humans; Male; Middle Aged; Polyethylene Glycols; Potassium Chloride; Rupture, Spontaneous; Sodium Bicarbonate; Sodium Chloride; Sulfates; Therapeutic Irrigation; Vomiting

Topics: Aged; Antacids; Bicarbonates; Humans; Male; Rupture, Spontaneous; Sodium; Sodium Bicarbonate; Stomach Rupture

Topics: Bicarbonates; Female; Humans; Middle Aged; Rupture, Spontaneous; Sodium; Sodium Bicarbonate; Stomach Rupture

Spontaneous rupture of the stomach is an uncommon condition with a usually poor prognosis. The rupture occurs as a result of a closed loop obstruction with increased pressure against the stomach wall. A case of stomach rupture occurring after hyperdistention of the stomach following ingestion of sodium bicarbonate is described and the pathophysiological mechanism is discussed.

Topics: Adult; Bicarbonates; Humans; Male; Postoperative Complications; Rupture, Spontaneous; Sodium; Sodium Bicarbonate; Stomach Rupture

Spontaneous rupture of the normal stomach is an unusual and highly lethal event. We present a case of spontaneous rupture of a normal stomach after ingestion of sodium bicarbonate, and review the seven similar cases previously reported.

Topics: Adult; Bicarbonates; Humans; Male; Rupture, Spontaneous; Sodium; Sodium Bicarbonate; Stomach Rupture

Topics: Antacids; Bicarbonates; Gastric Dilatation; Humans; Rupture, Spontaneous; Sodium; Sodium Bicarbonate; Stomach Rupture

Topics: Adult; Bicarbonates; Digestive System Diseases; Humans; Male; Rupture, Spontaneous; Sodium Bicarbonate; Stomach Diseases

Topics: Aged; Bicarbonates; Carbon Dioxide; Humans; Male; Pressure; Rupture, Spontaneous; Sodium Bicarbonate; Stomach Rupture

In our in vitro study of subarachnoid haemorrhage, the anaerobic incubation of CSF-blood mixture led to marked fall in the pH value thereof, which suggested to us that intracranial focal acidosis may play some role in the pathogenesis of cerebral vasospasm or disturbance of consciousness after the haemorrhage. To test this hypothesis, we treated 16 clinical cases of such disorders with carotid injection of 7% sodium bicarbonate solution. The treatment resulted in considerable improvement of the disturbance of consciousness by dilating the cerebral peripheral arteries; this we could observe angiographically 15 minutes after carotid injection. We found no morphological changes, however, in the spastic vessel itself up to 30 minutes after the injection. Given the result both of this study and of our previous experiments, we offer the hypothesis that the synthesizing process of thromboxane A2 and intracranial focal acidosis might play an important role in the pathogenesis of cerebral vasospasm.

Topics: Adolescent; Adult; Aged; Anaerobiosis; Bicarbonates; Child, Preschool; Consciousness Disorders; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Postoperative Complications; Rupture, Spontaneous; Sodium Bicarbonate; Subarachnoid Hemorrhage