sodium-bicarbonate and Priapism

sodium-bicarbonate has been researched along with Priapism* in 3 studies

Reviews

1 review(s) available for sodium-bicarbonate and Priapism

ArticleYear
Towards evidence based emergency medicine: Best BETs from the Manchester Royal Infirmary. Bet 1: The effectiveness of oral terbutaline in treatment of priapism.
    Emergency medicine journal : EMJ, 2011, Volume: 28, Issue:6

    Topics: Administration, Oral; Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Evidence-Based Emergency Medicine; Follow-Up Studies; Humans; Male; Middle Aged; Priapism; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Sodium Bicarbonate; Terbutaline; Treatment Outcome; United Kingdom; Young Adult

2011

Trials

1 trial(s) available for sodium-bicarbonate and Priapism

ArticleYear
Placebo-controlled study of oral terbutaline and pseudoephedrine in management of prostaglandin E1-induced prolonged erections.
    Urology, 1993, Volume: 42, Issue:1

    Prolonged erections, priapism, secondary to pharmacologic stimulation are usually treated by drainage of the corporeal bodies and irrigation with a sympathomimetic. To study the efficacy of oral medical therapy in the treatment of priapism, 75 patients with pharmacologically induced (prostaglandin E1) prolonged erections were randomized to receive terbutaline, pseudoephedrine, or placebo. Detumescence occurred in 36 percent, 28 percent, and 12 percent, respectively. Terbutaline was significantly better than placebo (p < 0.05) in achieving detumescence. The results of this study suggest that oral terbutaline should be considered in the initial management of pharmacologically induced prolonged erections.

    Topics: Alprostadil; Bicarbonates; Ephedrine; Erectile Dysfunction; Humans; Male; Priapism; Sodium; Sodium Bicarbonate; Terbutaline

1993

Other Studies

1 other study(ies) available for sodium-bicarbonate and Priapism

ArticleYear
From methylene blue (methylthionine chloride) to Al-Ghorab procedure: the therapy of priapism (our experience).
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2009, Volume: 81, Issue:4

    The better knowledge concerning the anatomo-physiology of erection has brought important changes to the management of priapism. We experimented with a staged therapeutic protocol forthis condition.. 17 patients, aged from 27 to 71 (mean age 43) were treated for ischemic priapism; the pathogenesis was idiopathic in 9 cases, in 4 cases secondary to intracavernous injection (IcI) of PGE1, in 2 cases to papaverine Icd, in 1 case to haemolympho-pathy and in another patient to treatement with heparin. Cavernous PO2, PCO2 and pH were checked. All patients underwent removal of 100 cc of blood, irrigation with NaHCO3 solution of the cavernous corpora and Methylen blue (MB) IcI 10 mg every 5 minutes 10 times, repeated twice.. From 3 to 6 hours from the beginning of therapy, detumescence was achieved in 10 cases. In 5 cases the priapism persisted and we administered adrenaline 20 pg every 5-10 minutes: 2 cases had detumescence respectively in 5 and 7 hours whereas in the patient with leukaemia the erection persisted and we desisted from further therapy; in 2 other cases the erection persisted and we did a distal cavernosum-glans shunt and the detumescence a was achieved in 30 and 58 hours respectively. In the last 2 cases, before adrenaline we administered an IcI of ethylephrine 5 mg every 5 minutes for 4-5 times but finally we had to perform a shunt. In all cases, during the treatment, and during the following 6-8 hours, we administered 200 mg of MB intravenous.. The introduction of oral drugs has changed the epidemiology of priapism. A better knowledge of the molecular mechanisms that govern the cavernous contraction and myorelaxation has allowed us to use adrenergic drugs and also the MB. This staged therapeutic protocol goes from a less invasive therapy (irrigation with NaHCO3, MB, ethylephrine, adrenaline) to a surgical procedure which must not be delayed and this progression could allow a reduction in the collateral effects.

    Topics: Adult; Aged; Drug Therapy, Combination; Enzyme Inhibitors; Epinephrine; Etilefrine; Humans; Male; Methylene Blue; Middle Aged; Priapism; Prostatectomy; Sodium Bicarbonate; Therapeutic Irrigation; Treatment Outcome; Vasoconstrictor Agents

2009