sodium-bicarbonate and Gastric-Dilatation

A case of distal renal tubular acidosis occurring as a transient complication in a 13-year-old female greyhound dog with gastric-dilatation-volvulus was diagnosed. The acute renal ischemia and inflammatory condition associated with this syndrome could be considered the main underlying mechanisms responsible for the acute, severe, and complicating renal tubular dysfunction.

Topics: Acidosis, Renal Tubular; Animals; Dog Diseases; Dogs; Female; Gastric Dilatation; Sodium Bicarbonate; Stomach Volvulus; Treatment Outcome

Thirty-seven of 53 diarrhoeic calves hospitalised for intravenous fluid therapy were classified as very severely acidotic (total carbon dioxide less than 8 mmol/litre) by using a Harleco apparatus. All the calves were given intravenously 10 to 20 litres of electrolyte solution which contained 144 mmol/litre sodium, 4 mmol/litre potassium, 113 mmol/litre chloride and 35 mmol/litre bicarbonate, and in addition the 37 very severely acidotic calves received 400 ml of 1M sodium bicarbonate in the first 5 litres of fluid administered. Sixteen of the 37 very severely acidotic calves had a distended right flank, suggesting the presence of a dilated fluid-filled viscus. Neither their history nor other clinical signs were useful predictors of the distension. The distended calves had significantly higher plasma concentrations of sodium and chloride, and significantly lower plasma creatinine concentrations than the calves which were not distended. Treatment was successful in all the 21 non-distended calves but four of the distended calves died despite treatment. The resolution of the distension in the successfully treated calves, coincided with a significant increase in plasma bicarbonate concentration and the passage of large amounts of malodorous mucoid faeces.

Topics: Abomasum; Acidosis; Animals; Anions; Blood Glucose; Blood Urea Nitrogen; Carbon Dioxide; Cattle; Cattle Diseases; Creatinine; Diarrhea; Electrolytes; Gastric Dilatation; Infusions, Intravenous; Isotonic Solutions; Lactic Acid; Sodium Bicarbonate

Topics: Antacids; Bicarbonates; Gastric Dilatation; Humans; Rupture, Spontaneous; Sodium; Sodium Bicarbonate; Stomach Rupture