sodium-bicarbonate and Candidiasis

sodium-bicarbonate has been researched along with Candidiasis* in 2 studies

Other Studies

2 other study(ies) available for sodium-bicarbonate and Candidiasis

Article	Year
Report: Synergism of sodium bicarbonate and baicalin against clinical Candida albicans isolates via broth microdilution method and checkerboard assay. Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:3 Invasive fungal infections caused by Candida albicans constitute a prevalent worldwide health problem. Due to limited antifungal agents available, more efforts have been made towards searching the novel anti-candida drugs with low cytotoxicity. The present study was aimed to investigate the antifungal activities of baicalin and/or sodium bicarbonate (SB) against 29 C. albicans isolates including 27 clinical ones. By using broth microdilution method and checkerboard assay, it was observed that the minimum inhibitory concentrations (MICs) of baicalin and SB alone were > 2048 μg/mL, and those of baicalin and SB in combination decreased 16-32 folds with fractional inhibitory concentration index (FICI) in a range of 0.094-0.375. The results presented the strong synergism between SB and baicalin in 27 clinical C. albicans isolates and provided an alternative choice against C. albicans. Topics: Antifungal Agents; Candida albicans; Candidiasis; Drug Synergism; Flavonoids; Humans; Microbial Sensitivity Tests; Sodium Bicarbonate	2019
[A study on urinary fungal infection]. Hinyokika kiyo. Acta urologica Japonica, 1983, Volume: 29, Issue:10 We analyzed 20 cases of urinary fungal infection experienced at our Department, during the last 2 years. Candida albicans was the most prevalent of the fungi affecting the urinary tract. Torulopsis glabrata and Candida tropicalis were also prevalent. Antibiotics, indwelling catheter and obstructive uropathy were the most prevalent predisposing factors of the fungal infection. Of 20 cases of fungal infection, 5 cases were cured only by elimination of the predisposing factors, and 15 cases were treated and resolved by administration of sodium bicarbonate, 5-fluorocytosine and or irrigation with amphotericin B. But one case of bilateral renal torulopsiosis developed into renal failure, and 4 cases died of the primary disease. Topics: Adolescent; Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Bicarbonates; Candida; Candidiasis; Child; Child, Preschool; Female; Flucytosine; Humans; Infant; Male; Middle Aged; Mycoses; Sodium; Sodium Bicarbonate; Urinary Catheterization; Urinary Tract Infections	1983

Article

Year

Report: Synergism of sodium bicarbonate and baicalin against clinical Candida albicans isolates via broth microdilution method and checkerboard assay.

Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:3

Invasive fungal infections caused by Candida albicans constitute a prevalent worldwide health problem. Due to limited antifungal agents available, more efforts have been made towards searching the novel anti-candida drugs with low cytotoxicity. The present study was aimed to investigate the antifungal activities of baicalin and/or sodium bicarbonate (SB) against 29 C. albicans isolates including 27 clinical ones. By using broth microdilution method and checkerboard assay, it was observed that the minimum inhibitory concentrations (MICs) of baicalin and SB alone were > 2048 μg/mL, and those of baicalin and SB in combination decreased 16-32 folds with fractional inhibitory concentration index (FICI) in a range of 0.094-0.375. The results presented the strong synergism between SB and baicalin in 27 clinical C. albicans isolates and provided an alternative choice against C. albicans.

Topics: Antifungal Agents; Candida albicans; Candidiasis; Drug Synergism; Flavonoids; Humans; Microbial Sensitivity Tests; Sodium Bicarbonate

2019

[A study on urinary fungal infection].

Hinyokika kiyo. Acta urologica Japonica, 1983, Volume: 29, Issue:10

We analyzed 20 cases of urinary fungal infection experienced at our Department, during the last 2 years. Candida albicans was the most prevalent of the fungi affecting the urinary tract. Torulopsis glabrata and Candida tropicalis were also prevalent. Antibiotics, indwelling catheter and obstructive uropathy were the most prevalent predisposing factors of the fungal infection. Of 20 cases of fungal infection, 5 cases were cured only by elimination of the predisposing factors, and 15 cases were treated and resolved by administration of sodium bicarbonate, 5-fluorocytosine and or irrigation with amphotericin B. But one case of bilateral renal torulopsiosis developed into renal failure, and 4 cases died of the primary disease.

Topics: Adolescent; Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Bicarbonates; Candida; Candidiasis; Child; Child, Preschool; Female; Flucytosine; Humans; Infant; Male; Middle Aged; Mycoses; Sodium; Sodium Bicarbonate; Urinary Catheterization; Urinary Tract Infections

1983