sodium-bicarbonate and Anemia--Sickle-Cell

The treatment of sickle cell disease is still mainly symptomatic. However, there have been major advances in understanding the pathophysiology of sickling syndromes. This in turn has led to a proper approach in the management of the sickle cell patient. This review summarises current treatment regimens in sickle cell disease.

Topics: Anemia, Sickle Cell; Bicarbonates; Blood Transfusion; Fluid Therapy; Genetic Counseling; Humans; Oxygen Inhalation Therapy; Sodium; Sodium Bicarbonate

The treatment of sickle cell disease is still primarily symptomatic. However, there have been major advances in understanding the pathophysiology of sickling syndromes. This in turn has led to a proper approach in the management of the sickle cell patient. This paper describes treatment regimens as we best understand them today.

Topics: Adult; Altitude; Analgesics; Anemia, Sickle Cell; Bicarbonates; Blood Transfusion; Child; Child, Preschool; Citrates; Citric Acid; Cold Temperature; Female; Fluid Therapy; Humans; Pregnancy; Pregnancy Complications, Hematologic; Premedication; Sodium Bicarbonate

Sickle cell anaemia is the most common hereditary haemoglobin pathology. It is found in either a homozygous or heterozygous form, associated in the latter case with other haemoglobinopathies. In view of the pathogenesis and the various related imbalances, amply confirmed by others, which can well prove disastrous, the pre, per and post-operative precautions to be adopted in such patients are assessed.

Topics: Acidosis; Adolescent; Anemia, Sickle Cell; Anesthesia; Bicarbonates; Blood Viscosity; Child; Child, Preschool; Genotype; Humans; Postoperative Care; Preoperative Care; Sickle Cell Trait; Sodium Bicarbonate