Compounds > sodium arsenite
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sodium arsenite and Cell Transformation, Neoplastic

sodium arsenite has been researched along with Cell Transformation, Neoplastic in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.98)18.7374
1990's2 (4.65)18.2507
2000's13 (30.23)29.6817
2010's22 (51.16)24.3611
2020's3 (6.98)2.80

Authors

AuthorsStudies
Chorley, BN; Corton, JC; Gunewardena, S; Klaassen, CD; Liu, J; Yue Cui, J1
Flora, SJS; Sathua, K; Srivastava, S1
Beland, FA; Borowa-Mazgaj, B; Pogribny, IP; Steward, CR; Tryndyak, VP1
Costa, M; Eldridge, WJ; Jakobsen, NM; Muñoz, A; Sørensen, H; Wax, A1
Dai, H; Gu, S; Sun, D; Zhang, Z1
An, Y; Deng, H; Li, C; Ni, Y; Wang, X; Zhu, Z1
Guo, F; Guo, S; Huang, S; Kawanishi, S; Ma, N; Murata, M; Ohnishi, S; Xiao, X; Yang, Q1
Li, Y; Liu, Q; Luo, F; Pang, Y; Wang, B; Xu, W; Xu, Y; Zhao, Y1
Hidalgo-Miranda, A; Martínez-Pacheco, M; Rojas, E; Romero-Córdoba, S; Valverde, M1
Ngalame, NN; Person, RJ; Tokar, EJ; Waalkes, MP; Xu, Y1
Jiang, R; Li, Y; Liu, Q; Luo, F; Wang, B; Xu, W; Xu, Y; Zhang, A; Zhao, Y1
Ngalame, NN; Person, RJ; Tokar, EJ; Waalkes, MP1
Huang, C; Li, J; Liang, Y; Liu, J; Mi, X; Zhang, D1
Ji, J; Jing, J; Liu, Q; Liu, Y; Lu, X; Luo, F; Shi, L; Wang, B; Xu, W; Xu, Y; Zheng, G1
Chen, KC; Fondufe-Mittendorf, YN; Godfrey, SG; Ma, Y; Melikishvili, M; Riedmann, C; Rouchka, EC; Zhang, Z1
Dai, J; Kim, D; Park, YH; Zhang, Z1
An, Y; Chen, M; Deng, H; Li, C; Ma, Y; Tong, J; Wang, D; Wang, X; Xu, X; Yamanaka, K; Yang, X; Zhu, Z1
Chen, C; Gu, S; Jiang, X; Zhang, Z1
Burchiel, SW; Cooper, KL; Hudson, LG; Huestis, J; Liu, KJ; Xu, H; Zhou, X1
Arita, A; Costa, M; Li, Q; Sun, H; Zhou, X1
Ahlborn, GJ; Allen, JW; Corton, JC; Delker, DA; Diwan, BA; Kitchin, KT; Knapp, G; Nelson, GM; Ren, H; Waalkes, MP1
Chiu, JF; Lee, LS; Li, G; Li, M; Tsao, SW1
Li, Y; Ling, M; Liu, Q; Pang, Y; Shen, L; Wang, X; Xu, H; Xu, Y; Zhou, J1
Jiang, R; Li, Y; Ling, M; Liu, Q; Pang, Y; Shen, L; Wang, X; Xu, Y; Zhang, J; Zhao, Y; Zhou, J; Zhou, Y1
Bower, KA; Chen, G; Frank, JA; Liao, M; Luo, J; Qi, Y; Shen, HM; Shi, X; Xu, M; Zhang, T1
Jiang, R; Li, Y; Liu, Q; Pang, Y; Shen, L; Wang, X; Xu, Y; Zhang, J; Zhao, Y; Zhou, J; Zhou, Y1
Furuta, A; Kato, M; Khalequzzaman, M; Kumasaka, MY; Nakajima, T; Nizam, S; Ohnuma, S; Shekhar, HU; Shimizu, S; Yajima, I; Yamanoshita, O1
Barrett, JC; Takahashi, M; Tsutsui, T1
Geisenhoffer, KM; Germolec, DR; Trouba, KJ1
Barrett, JC; Chen, H; Diwan, BA; Li, S; Liu, J; Waalkes, MP1
Achanzar, WE; Benbrahim-Tallaa, L; Styblo, M; Waalkes, MP; Waterland, RA; Webber, MM1
Hwang, BJ; Steinberg, M; Utti, C1
Chai, CY; Chen, WT; Huang, YC; Hung, WC; Kang, WY2
Ahlborn, GJ; Allen, JW; Chen, Y; Delker, DA; Kitchin, KT; Knapp, G; Nelson, GM; O'Brien, T; Ouyang, M; Roop, BC; Ward, WO1
Coppin, JF; Qu, W; Waalkes, MP1
Davison, AJ; Kowalski, LA; Tsang, SS1
Coogan, TP; Diwan, BA; Waalkes, MP; Young, MR; Zhao, CQ1
Chen, H; Liu, J; Merrick, BA; Waalkes, MP1
Chen, H; Diwan, BA; Liu, J; Merrick, BA; Waalkes, MP; Zhao, CQ1
Bertolero, F; Pozzi, G; Sabbioni, E; Saffiotti, U1
Huang, RY; Jan, KY; Lee, TC1
Barrett, JC; Lee, TC; Oshimura, M1

Other Studies

43 other study(ies) available for sodium arsenite and Cell Transformation, Neoplastic

ArticleYear
Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice.
    Toxicology, 2020, 04-15, Volume: 435

    Topics: 5-Methylcytosine; Animals; Arsenites; Cell Transformation, Neoplastic; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Gestational Age; Liver; Liver Neoplasms; Male; Maternal Exposure; Mice, Inbred C3H; MicroRNAs; Pregnancy; Sodium Compounds

2020
MiADMSA ameliorate arsenic induced urinary bladder carcinogenesis in vivo and in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Arsenites; Cacodylic Acid; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; DNA Damage; Humans; Male; Matrix Metalloproteinase 9; Nitrosative Stress; Rats, Sprague-Dawley; Sodium Compounds; Succimer; Survivin; Urinary Bladder Neoplasms

2020
Epigenetic effects of low-level sodium arsenite exposure on human liver HepaRG cells.
    Archives of toxicology, 2020, Volume: 94, Issue:12

    Topics: Arsenites; Cell Line, Tumor; Cell Transformation, Neoplastic; Claudins; DNA Damage; DNA Methylation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Hepatocytes; Histones; Humans; Liver Neoplasms; Mutation; Sodium Compounds

2020
Cellular shear stiffness reflects progression of arsenic-induced transformation during G1.
    Carcinogenesis, 2018, 02-09, Volume: 39, Issue:2

    Topics: Arsenites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; G1 Phase; Humans; Respiratory Mucosa; Shear Strength; Sodium Compounds

2018
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    Toxicology letters, 2018, Volume: 292

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Apoptosis; Arsenites; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Methyltransferases; MicroRNAs; Nuclear Proteins; Phenotype; RNA Splicing Factors; Signal Transduction; Sodium Compounds; Time Factors

2018
[Effect of low-dose exposure to sodium arsenite on proliferation of HBE and HaCaT cells].
    Wei sheng yan jiu = Journal of hygiene research, 2017, Volume: 46, Issue:1

    Topics: Arsenic; Arsenites; Cell Cycle; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Epithelial Cells; Humans; Keratinocytes; Sodium Compounds; Up-Regulation

2017
CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure.
    European journal of histochemistry : EJH, 2013, Jan-14, Volume: 57, Issue:1

    Topics: Animals; Arsenic; Arsenites; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; NF-kappa B; Skin; Skin Neoplasms; Sodium Compounds; Transplantation, Heterologous; Tumor Suppressor Protein p53

2013
Involvement of HIF-2α-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells.
    Toxicology and applied pharmacology, 2013, Oct-15, Volume: 272, Issue:2

    Topics: Arsenites; Basic Helix-Loop-Helix Transcription Factors; Bronchi; Cell Transformation, Neoplastic; Cytokines; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Real-Time Polymerase Chain Reaction; Sodium Compounds; Time Factors; Up-Regulation

2013
MRNA and miRNA expression patterns associated to pathways linked to metal mixture health effects.
    Gene, 2014, Jan-10, Volume: 533, Issue:2

    Topics: Animals; Arsenites; BALB 3T3 Cells; Cadmium Chloride; Cell Transformation, Neoplastic; Gene Expression; Gene Expression Profiling; Health; Metals; Mice; Microarray Analysis; MicroRNAs; Organometallic Compounds; RNA, Messenger; Signal Transduction; Sodium Compounds; Toxicity Tests

2014
Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 138, Issue:2

    Topics: Arsenites; Blotting, Western; Carcinogens, Environmental; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression; Genes, ras; Humans; Male; MicroRNAs; Neoplastic Stem Cells; Prostate; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Real-Time Polymerase Chain Reaction; Sodium Compounds

2014
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB.
    Toxicology letters, 2014, Jun-05, Volume: 227, Issue:2

    Topics: Animals; Arsenites; Azacitidine; Cell Line; Cell Transformation, Neoplastic; Decitabine; Epigenesis, Genetic; Gene Silencing; Humans; Keratinocytes; Mice; Mice, Nude; MicroRNAs; Neoplastic Stem Cells; NF-kappa B; ras Proteins; Sodium Compounds

2014
Silencing KRAS overexpression in arsenic-transformed prostate epithelial and stem cells partially mitigates malignant phenotype.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 142, Issue:2

    Topics: Animals; Arsenites; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Male; Mice, Nude; Neoplastic Stem Cells; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; RNA Interference; RNA, Small Interfering; Sodium Compounds; Xenograft Model Antitumor Assays

2014
The N-terminal region of p27 inhibits HIF-1α protein translation in ribosomal protein S6-dependent manner by regulating PHLPP-Ras-ERK-p90RSK axis.
    Cell death & disease, 2014, Nov-20, Volume: 5

    Topics: Animals; Arsenites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; NIH 3T3 Cells; Nuclear Proteins; Phosphoprotein Phosphatases; Protein Biosynthesis; Protein Structure, Tertiary; ras Proteins; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Sodium Compounds

2014
MicroRNA-21, up-regulated by arsenite, directs the epithelial-mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4.
    Toxicology letters, 2015, Jan-05, Volume: 232, Issue:1

    Topics: Apoptosis Regulatory Proteins; Arsenites; Bronchi; Cell Line, Transformed; Cell Movement; Cell Transformation, Neoplastic; Epithelial Cells; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; MicroRNAs; Nuclear Proteins; RNA Interference; RNA-Binding Proteins; Signal Transduction; Sodium Compounds; Time Factors; Transfection; Twist-Related Protein 1; Up-Regulation

2015
Inorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patterns.
    BMC genomics, 2015, Mar-19, Volume: 16

    Topics: Apoptosis; Arsenites; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Chromatin; DNA Fragmentation; Epithelial-Mesenchymal Transition; HeLa Cells; Humans; MicroRNAs; Nucleosomes; RNA Splicing; Signal Transduction; Sodium Compounds; Transcriptome

2015
Human bronchial epithelial BEAS-2B cells, an appropriate in vitro model to study heavy metals induced carcinogenesis.
    Toxicology and applied pharmacology, 2015, Sep-15, Volume: 287, Issue:3

    Topics: Animals; Arsenites; Bronchi; Cell Line; Cell Transformation, Neoplastic; Chromates; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Heavy Metal Poisoning; Humans; Lung Neoplasms; Metals, Heavy; Mice, Nude; Mutation, Missense; Phosphorylation; Poisoning; Promoter Regions, Genetic; Risk Assessment; Signal Transduction; Sodium Compounds; Time Factors; Transcriptional Activation; Tumor Suppressor Protein p53

2015
Continuous activation of Nrf2 and its target antioxidant enzymes leads to arsenite-induced malignant transformation of human bronchial epithelial cells.
    Toxicology and applied pharmacology, 2015, Dec-01, Volume: 289, Issue:2

    Topics: Antioxidants; Arsenites; Bronchi; Carcinogens; Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; Epithelial Cells; Heme Oxygenase-1; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); Neoplasm Invasiveness; NF-E2-Related Factor 2; Oxidative Stress; Phenotype; Reactive Oxygen Species; RNA Interference; Signal Transduction; Sodium Compounds; Superoxide Dismutase; Time Factors; Transfection

2015
[Role of nuclear factor E2 related factor 2 signaling pathway in malignant transformation induced by sodium arsenite].
    Wei sheng yan jiu = Journal of hygiene research, 2016, Volume: 45, Issue:3

    Topics: Arsenites; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Heme Oxygenase-1; Humans; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Signal Transduction; Sodium Compounds

2016
S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: Arsenites; Cell Line; Cell Transformation, Neoplastic; Cysteine; DNA Damage; DNA Repair; Free Radical Scavengers; Humans; Keratinocytes; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrosation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Protein Processing, Post-Translational; Sodium Compounds; Time Factors; Ultraviolet Rays; Zinc; Zinc Fingers

2016
Effects of nickel, chromate, and arsenite on histone 3 lysine methylation.
    Toxicology and applied pharmacology, 2009, Apr-01, Volume: 236, Issue:1

    Topics: Arsenites; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromates; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Lysine; Methylation; Nickel; Potassium Compounds; Protein Processing, Post-Translational; Sodium Compounds; Time Factors

2009
Transcriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic.
    Toxicology, 2009, Dec-21, Volume: 266, Issue:1-3

    Topics: Age Factors; Aging; Animals; Arsenites; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Gestational Age; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Pregnancy; Prenatal Exposure Delayed Effects; Sodium Compounds; Transcription, Genetic

2009
Molecular changes during arsenic-induced cell transformation.
    Journal of cellular physiology, 2011, Volume: 226, Issue:12

    Topics: Animals; Antioxidants; Arsenites; Carcinogens, Environmental; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Glutathione; MAP Kinase Kinase Kinases; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; ras Proteins; Rats; Reactive Oxygen Species; Respiratory Mucosa; Signal Transduction; Sodium Compounds; Superoxide Dismutase; Thioredoxins

2011
Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite.
    Toxicology letters, 2011, Oct-10, Volume: 206, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Arsenites; Carcinogens, Environmental; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Fibroblasts; G1 Phase; Humans; Lung; Lung Neoplasms; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 8; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; RNA Interference; RNA, Small Interfering; Signal Transduction; Sodium Compounds; Up-Regulation

2011
Opposed arsenite-mediated regulation of p53-survivin is involved in neoplastic transformation, DNA damage, or apoptosis in human keratinocytes.
    Toxicology, 2012, Oct-28, Volume: 300, Issue:3

    Topics: Animals; Apoptosis; Arsenites; Blotting, Southwestern; Blotting, Western; Cell Culture Techniques; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA Damage; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Humans; Immunoprecipitation; Inhibitor of Apoptosis Proteins; Keratinocytes; MAP Kinase Signaling System; Mice; Mice, Nude; Mitochondrial Proteins; Neoplasms; Real-Time Polymerase Chain Reaction; Sodium Compounds; Survivin; Tumor Suppressor Protein p53

2012
Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 130, Issue:2

    Topics: Animals; Arsenites; Autophagy; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Microtubule-Associated Proteins; Mitochondria; Oxidative Stress; Protein Kinase Inhibitors; Reactive Oxygen Species; Respiratory Mucosa; Signal Transduction; Sirolimus; Sodium Compounds; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tumor Burden

2012
EMT and CSC-like properties mediated by the IKKβ/IκBα/RelA signal pathway via the transcriptional regulator, Snail, are involved in the arsenite-induced neoplastic transformation of human keratinocytes.
    Archives of toxicology, 2013, Volume: 87, Issue:6

    Topics: Arsenites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Humans; I-kappa B Kinase; I-kappa B Proteins; Keratinocytes; Neoplastic Stem Cells; NF-KappaB Inhibitor alpha; Phenotype; Signal Transduction; Snail Family Transcription Factors; Sodium Compounds; Time Factors; Transcription Factor RelA; Transcription Factors

2013
Enhanced carcinogenicity by coexposure to arsenic and iron and a novel remediation system for the elements in well drinking water.
    Archives of toxicology, 2013, Volume: 87, Issue:3

    Topics: Adsorption; Aluminum Hydroxide; Arsenites; Bangladesh; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Chelating Agents; Drinking Water; Drug Synergism; Environmental Monitoring; Environmental Restoration and Remediation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Iron Compounds; Keratinocytes; Magnesium Hydroxide; Neoplasm Invasiveness; Risk Assessment; Skin Neoplasms; Sodium Compounds; src-Family Kinases; Water Pollutants, Chemical

2013
Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters.
    International journal of cancer, 2002, Jun-10, Volume: 99, Issue:5

    Topics: Animals; Animals, Newborn; Arsenates; Arsenites; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Deoxyribonuclease HpaII; DNA Methylation; Embryo, Mammalian; Gene Amplification; Genes, ras; Mesocricetus; Neoplasm Transplantation; Proto-Oncogene Proteins c-myc; RNA, Messenger; Sodium Compounds

2002
Sodium arsenite-induced stress-related gene expression in normal human epidermal, HaCaT, and HEL30 keratinocytes.
    Environmental health perspectives, 2002, Volume: 110 Suppl 5

    Topics: Animals; Arsenites; Blotting, Northern; Cell Transformation, Neoplastic; Enzyme Inhibitors; Gene Expression Regulation; Glutathione; Humans; Keratinocytes; Mice; Oxidation-Reduction; Protein Serine-Threonine Kinases; Signal Transduction; Sodium Compounds

2002
Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis.
    Carcinogenesis, 2004, Volume: 25, Issue:9

    Topics: Animals; Arsenites; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cyclin D1; DNA Methylation; Estrogen Receptor alpha; Gene Expression Profiling; Immunoenzyme Techniques; Liver; Male; Mice; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Sodium Compounds; Sulfhydryl Reagents; Water

2004
Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation.
    Toxicology and applied pharmacology, 2005, Aug-15, Volume: 206, Issue:3

    Topics: Arsenites; Cell Transformation, Neoplastic; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; Epithelial Cells; Gene Expression; Genes, ras; Humans; Male; Matrix Metalloproteinase 9; Mutation; Oligonucleotide Array Sequence Analysis; Prostate; Sodium Compounds

2005
Induction of cyclin D1 by submicromolar concentrations of arsenite in human epidermal keratinocytes.
    Toxicology and applied pharmacology, 2006, Dec-01, Volume: 217, Issue:2

    Topics: Arsenites; Carcinogens; Cell Cycle; Cell Proliferation; Cell Separation; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; CREB-Binding Protein; Cyclin D; Cyclins; DNA; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Epidermis; Flow Cytometry; Humans; Keratinocytes; Polymerase Chain Reaction; Protein Binding; RNA, Messenger; Sodium Compounds; Time Factors; Transcription Factor AP-1; Up-Regulation

2006
Arsenic salts induced autophagic cell death and hypermethylation of DAPK promoter in SV-40 immortalized human uroepithelial cells.
    Toxicology letters, 2007, Aug-30, Volume: 173, Issue:1

    Topics: Apoptosis Regulatory Proteins; Arsenites; Autophagy; Beclin-1; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; CpG Islands; Death-Associated Protein Kinases; DNA Methylation; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Membrane Proteins; Microscopy, Electron, Transmission; Polymerase Chain Reaction; Promoter Regions, Genetic; Simian virus 40; Sodium Compounds; Up-Regulation; Urothelium

2007
Expression of STAT3 and Bcl-6 oncoprotein in sodium arsenite-treated SV-40 immortalized human uroepithelial cells.
    Toxicology letters, 2007, Aug-30, Volume: 173, Issue:1

    Topics: Arsenites; Blotting, Western; Carcinogens; Cell Line, Transformed; Cell Shape; Cell Transformation, Neoplastic; Cell Transformation, Viral; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Janus Kinase 2; Phosphorylation; Proto-Oncogene Proteins c-bcl-6; Signal Transduction; Simian virus 40; Sodium Compounds; STAT3 Transcription Factor; Urothelium

2007
Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite.
    Toxicology and applied pharmacology, 2008, Mar-15, Volume: 227, Issue:3

    Topics: Animals; Arsenites; Cell Transformation, Neoplastic; DNA Methyltransferase 3A; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Profiling; Mice; Mice, Transgenic; Skin; Skin Neoplasms; Sodium Compounds

2008
Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells.
    The Journal of biological chemistry, 2008, Jul-11, Volume: 283, Issue:28

    Topics: Adenosylhomocysteinase; Arsenites; Cell Line; Cell Transformation, Neoplastic; Cystathionine beta-Synthase; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Homocysteine; Humans; Male; Methionine Adenosyltransferase; Multidrug Resistance-Associated Proteins; Prostate; S-Adenosylmethionine; Sodium Compounds

2008
Arsenic and chromium enhance transformation of bovine papillomavirus DNA-transfected C3H/10T1/2 cells.
    Cancer letters, 1996, May-15, Volume: 103, Issue:1

    Topics: Animals; Arsenates; Arsenites; Bovine papillomavirus 1; Carcinogens; Cattle; Cell Line; Cell Transformation, Neoplastic; Chromates; Chromium Compounds; DNA, Viral; Drug Synergism; Humans; Mice; Mice, Inbred C3H; Potassium Compounds; Sodium Compounds; Sulfates; Transfection; Vanadates; Vanadium Compounds

1996
Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Sep-30, Volume: 94, Issue:20

    Topics: Animals; Arsenites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Gene Expression; Mice; Mice, Nude; Rats; Rats, Inbred F344; Sodium Compounds

1997
Genetic events associated with arsenic-induced malignant transformation: applications of cDNA microarray technology.
    Molecular carcinogenesis, 2001, Volume: 30, Issue:2

    Topics: Animals; Apoptosis; Arsenites; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Cytokines; DNA, Complementary; DNA, Neoplasm; Gene Expression; Gene Expression Profiling; Growth Substances; Hepatocytes; Humans; Image Processing, Computer-Assisted; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Signal Transduction; Sodium Compounds

2001
Association of c-myc overexpression and hyperproliferation with arsenite-induced malignant transformation.
    Toxicology and applied pharmacology, 2001, Sep-15, Volume: 175, Issue:3

    Topics: Animals; Arsenites; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Dose-Response Relationship, Drug; Gene Expression; Hepatocytes; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sodium Compounds; Time Factors; Up-Regulation

2001
Cellular uptake and metabolic reduction of pentavalent to trivalent arsenic as determinants of cytotoxicity and morphological transformation.
    Carcinogenesis, 1987, Volume: 8, Issue:6

    Topics: Animals; Arsenates; Arsenic; Arsenites; Biological Transport; Biotransformation; Cell Transformation, Neoplastic; Cells, Cultured; Kinetics; Mice; Mice, Inbred BALB C; Sodium Compounds

1987
Different modes of action of sodium arsenite, 3-aminobenzamide, and caffeine on the enhancement of ethyl methanesulfonate clastogenicity.
    Cytogenetics and cell genetics, 1986, Volume: 41, Issue:4

    Topics: Animals; Arsenic; Arsenites; Benzamides; Caffeine; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Chromatids; Chromosome Aberrations; Cricetinae; Cricetulus; Female; Methyl Methanesulfonate; Ovary; Sodium Compounds; Sulfhydryl Reagents

1986
Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture.
    Carcinogenesis, 1985, Volume: 6, Issue:10

    Topics: Animals; Arsenates; Arsenic; Arsenites; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cricetinae; Drug Resistance; Mutation; Ouabain; Sister Chromatid Exchange; Sodium Compounds; Thioguanine

1985