sl0101 and Precursor-Cell-Lymphoblastic-Leukemia-Lymphoma

sl0101 has been researched along with Precursor-Cell-Lymphoblastic-Leukemia-Lymphoma* in 1 studies

Other Studies

1 other study(ies) available for sl0101 and Precursor-Cell-Lymphoblastic-Leukemia-Lymphoma

Article	Year
RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts. Cell death and differentiation, 2017, Volume: 24, Issue:2 Deregulated proliferation is key to tumor progression. Although unrestricted proliferation of solid tumor cells correlates with the cold-shock protein Y-box (YB)-binding protein-1 accumulation in the nuclei, little is known about its expression and function in hematopoietic malignancies, such as T-cell acute lymphoblastic leukemia (T-ALL). Here we show that YB-1 protein is highly enriched in the nuclei of activated T cells and malignant human T-ALL cell lines but not in resting T cells. YB-1 S Topics: Adolescent; Adult; Aged; Benzopyrans; CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Enterotoxins; Female; Humans; Jurkat Cells; Male; Middle Aged; Monosaccharides; Mutagenesis, Site-Directed; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Y-Box-Binding Protein 1; Young Adult	2017

Article

Year

RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts.

Cell death and differentiation, 2017, Volume: 24, Issue:2

Deregulated proliferation is key to tumor progression. Although unrestricted proliferation of solid tumor cells correlates with the cold-shock protein Y-box (YB)-binding protein-1 accumulation in the nuclei, little is known about its expression and function in hematopoietic malignancies, such as T-cell acute lymphoblastic leukemia (T-ALL). Here we show that YB-1 protein is highly enriched in the nuclei of activated T cells and malignant human T-ALL cell lines but not in resting T cells. YB-1 S

Topics: Adolescent; Adult; Aged; Benzopyrans; CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Enterotoxins; Female; Humans; Jurkat Cells; Male; Middle Aged; Monosaccharides; Mutagenesis, Site-Directed; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Y-Box-Binding Protein 1; Young Adult

2017