sk&f 97541 has been researched along with Seizures in 1 studies
3-aminopropyl(methyl)phosphinic acid: structure given in first source; GABA-A receptor antagonist
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It suppressed tonic phase of generalized seizures induced by pentetrazol in 7-, 12- and 18-day-old rats and increased their latency in 7- and 12-day-old animals." | 1.35 | Anticonvulsant action of GABA-B receptor agonist SKF97541 differs from that of baclofen. ( Mares, P, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mares, P | 1 |
1 other study available for sk&f 97541 and Seizures
| Article | Year |
|---|---|
Anticonvulsant action of GABA-B receptor agonist SKF97541 differs from that of baclofen.
Topics: Age Factors; Animals; Anticonvulsants; Baclofen; Disease Models, Animal; Dose-Response Relationship, | 2008 |