sk&f 86002 has been researched along with Parkinson Disease in 1 studies
6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole: inhibits p38 MAP kinase
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iba, M | 1 |
| Kim, C | 1 |
| Kwon, S | 1 |
| Szabo, M | 1 |
| Horan-Portelance, L | 1 |
| Peer, CJ | 1 |
| Figg, WD | 1 |
| Reed, X | 1 |
| Ding, J | 1 |
| Lee, SJ | 1 |
| Rissman, RA | 1 |
| Cookson, MR | 1 |
| Overk, C | 1 |
| Wrasidlo, W | 1 |
| Masliah, E | 1 |
1 other study available for sk&f 86002 and Parkinson Disease
| Article | Year |
|---|---|
Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD.
Topics: alpha-Synuclein; Animals; Humans; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 14; Neuro | 2023 |