sk&f 86002 has been researched along with Inflammation in 5 studies
6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole: inhibits p38 MAP kinase
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vivo, rolipram inhibited arachidonic acid-induced inflammation in the mouse, while the low Km-cyclic-GMP PDE inhibitor, zaprinast, did not inhibit." | 3.68 | Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response. ( Breton, J; Griswold, DE; Marshall, PJ; Torphy, TJ; Webb, EF; White, JR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Griswold, DE | 5 |
| Webb, EF | 4 |
| Breton, J | 1 |
| White, JR | 1 |
| Marshall, PJ | 3 |
| Torphy, TJ | 1 |
| Hillegass, LM | 1 |
| Hoffstein, S | 1 |
| Hillegass, L | 1 |
| Bender, PE | 1 |
| Hanna, N | 3 |
| Godfrey, R | 1 |
| Newton, J | 1 |
| DiMartino, MJ | 1 |
| Sarau, HM | 1 |
| Gleason, JG | 1 |
| Poste, G | 1 |
| Webb, E | 1 |
| Schwartz, L | 1 |
5 other studies available for sk&f 86002 and Inflammation
| Article | Year |
|---|---|
Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic A | 1993 |
Induction of plasma exudation and inflammatory cell infiltration by leukotriene C4 and leukotriene B4 in mouse peritonitis.
Topics: Animals; Ascites; Capillary Permeability; Chemotaxis, Leukocyte; Colchicine; Drug Interactions; Imid | 1991 |
Inhibition of inflammatory cell infiltration by bicyclic imidazoles, SK&F 86002 and SK&F 104493.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis, Leukocyte; Cyclophosphamide; Dinoprost | 1989 |
SK&F 86002: a structurally novel anti-inflammatory agent that inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; | 1987 |
Arachidonic acid-induced inflammation: inhibition by dual inhibitor of arachidonic acid metabolism, SK&F 86002.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Ibuprofen; Imidazoles; Infla | 1987 |