sk&f 86002 has been researched along with Disease Models, Animal in 3 studies
6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole: inhibits p38 MAP kinase
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of a new, structurally novel, dual inhibitor of arachidonic acid (AA) metabolism, SK&F 86002, was studied in two murine models of endotoxin shock." | 7.67 | Protective effect of SK&F 86002, a novel dual inhibitor of arachidonic acid metabolism, in murine models of endotoxin shock: inhibition of tumor necrosis factor as a possible mechanism of action. ( Badger, AM; Hanna, N; Olivera, D; Talmadge, JE, 1989) |
| "The protective effects of altered arachidonic acid metabolism, using either methylprednisolone or a dual cyclooxygenase and 5-lipoxygenase inhibitor (SK&F 86002), were compared in a rat model of adult respiratory distress syndrome (ARDS)." | 3.68 | Therapeutic intervention in a rat model of ARDS: I. Dual inhibition of arachidonic acid metabolism. ( Quinlan, MF; Schwartz, LW; Turner, CR; Wheeldon, EB, 1990) |
| "The effect of a new, structurally novel, dual inhibitor of arachidonic acid (AA) metabolism, SK&F 86002, was studied in two murine models of endotoxin shock." | 3.67 | Protective effect of SK&F 86002, a novel dual inhibitor of arachidonic acid metabolism, in murine models of endotoxin shock: inhibition of tumor necrosis factor as a possible mechanism of action. ( Badger, AM; Hanna, N; Olivera, D; Talmadge, JE, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, HL | 1 |
| Hu, WY | 1 |
| Jiang, LH | 1 |
| Li, L | 1 |
| Gaung, XF | 1 |
| Xiao, ZC | 1 |
| Turner, CR | 1 |
| Quinlan, MF | 1 |
| Schwartz, LW | 1 |
| Wheeldon, EB | 1 |
| Badger, AM | 1 |
| Olivera, D | 1 |
| Talmadge, JE | 1 |
| Hanna, N | 1 |
3 other studies available for sk&f 86002 and Disease Models, Animal
| Article | Year |
|---|---|
p38 MAPK Inhibition Improves Synaptic Plasticity and Memory in Angiotensin II-dependent Hypertensive Mice.
Topics: Angiotensin II; Animals; Dendritic Spines; Disease Models, Animal; Hippocampus; Humans; Hypertension | 2016 |
Therapeutic intervention in a rat model of ARDS: I. Dual inhibition of arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Capillary Permeability; | 1990 |
Protective effect of SK&F 86002, a novel dual inhibitor of arachidonic acid metabolism, in murine models of endotoxin shock: inhibition of tumor necrosis factor as a possible mechanism of action.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dexamethasone; Disease Models, Animal; Galactosamine; | 1989 |