sk&f 86002 has been researched along with Crohn Disease in 1 studies
6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole: inhibits p38 MAP kinase
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In active ulcerative colitis, A23187 and antihuman IgE induced significantly higher stimulation of PAF synthesis compared to their effects on normal mucosa." | 1.28 | Cytokines and platelet-activating factor in human inflamed colonic mucosa. ( Eliakim, R; Karmeli, F; Ligumsky, M; Rachmilewitz, D; Simon, P, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rachmilewitz, D | 1 |
| Eliakim, R | 1 |
| Simon, P | 1 |
| Ligumsky, M | 1 |
| Karmeli, F | 1 |
1 other study available for sk&f 86002 and Crohn Disease
| Article | Year |
|---|---|
Cytokines and platelet-activating factor in human inflamed colonic mucosa.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Anti-Idiotypic; Calcimyci | 1992 |