sk&f 82958 has been researched along with Parkinsonian Disorders in 9 studies
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When biperiden was combined with SKF-82958, contraversive circling also was enhanced and ipsiversive circling decreased." | 1.35 | Biperiden enhances L-DOPA methyl ester and dopamine D(l) receptor agonist SKF-82958 but antagonizes D(2)/D(3) receptor agonist rotigotine antihemiparkinsonian actions. ( Domino, EF; Ni, L, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (88.89) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barroso-Chinea, P | 1 |
| Thiolat, ML | 1 |
| Bido, S | 1 |
| Martinez, A | 1 |
| Doudnikoff, E | 1 |
| Baufreton, J | 1 |
| Bourdenx, M | 1 |
| Bloch, B | 1 |
| Bezard, E | 1 |
| Martin-Negrier, ML | 1 |
| Domino, EF | 1 |
| Ni, L | 1 |
| Taymans, JM | 1 |
| Kia, HK | 1 |
| Groenewegen, HJ | 1 |
| Leysen, JE | 1 |
| Langlois, X | 1 |
| Glavan, G | 2 |
| Zivin, M | 2 |
| Kirik, D | 1 |
| Rosenblad, C | 1 |
| Bjorklund, A | 1 |
| Mandel, RJ | 1 |
| Di Marzo, V | 1 |
| Hill, MP | 1 |
| Bisogno, T | 1 |
| Crossman, AR | 1 |
| Brotchie, JM | 1 |
| Zorec, R | 1 |
| Babic, K | 1 |
| Sket, D | 1 |
| Blanchet, PJ | 2 |
| Calon, F | 2 |
| Morissette, M | 2 |
| Goulet, M | 2 |
| Grondin, R | 2 |
| Lévesque, D | 1 |
| Bédard, PJ | 2 |
| Di Paolo, T | 2 |
| Ghribi, O | 1 |
9 other studies available for sk&f 82958 and Parkinsonian Disorders
| Article | Year |
|---|---|
D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly.
Topics: Animals; Benzazepines; Cells, Cultured; Corpus Striatum; Dopamine Agonists; Mice; Mice, Inbred C57BL | 2015 |
Biperiden enhances L-DOPA methyl ester and dopamine D(l) receptor agonist SKF-82958 but antagonizes D(2)/D(3) receptor agonist rotigotine antihemiparkinsonian actions.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Benza | 2008 |
Bilateral control of brain activity by dopamine D1 receptors: evidence from induction patterns of regulator of G protein signaling 2 and c-fos mRNA in D1-challenged hemiparkinsonian rats.
Topics: Animals; Benzazepines; Brain; Dopamine Agonists; Functional Laterality; Gene Expression Regulation; | 2005 |
Differential expression of striatal synaptotagmin mRNA isoforms in hemiparkinsonian rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Brain; Corpus Striatum; Disease Models, Animal | 2005 |
Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.
Topics: Animals; Benzazepines; Corpus Striatum; Dependovirus; Dopamine Agonists; Female; Gene Transfer Techn | 2000 |
Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease.
Topics: Animals; Arachidonic Acids; Benzazepines; Cannabinoid Receptor Modulators; Cannabinoids; Dopamine Ag | 2000 |
Dopaminergic regulation of synaptotagmin I and IV mRNAs in hemiparkinsonian rats.
Topics: Animals; Benzazepines; Calcium-Binding Proteins; Denervation; Dopamine; Dopamine Agonists; Down-Regu | 2000 |
Regulation of dopamine receptors and motor behavior following pulsatile and continuous dopaminergic replacement strategies in the MPTP primate model.
Topics: Aminoquinolines; Animals; Behavior, Animal; Benzazepines; Cabergoline; Disease Models, Animal; Dopam | 2001 |
Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Corpus Striatum; Dopamine Agoni | 2002 |