sk&f 81297 has been researched along with Seizures in 1 studies
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These seizure episodes parallel the hyperactivation of the mTOR signaling in the hippocampus, leading to disrupted long-term potentiation (LTP) in the dentate gyrus (DG) and altered recognition memories." | 1.40 | Repeated stimulation of dopamine D1-like receptor and hyperactivation of mTOR signaling lead to generalized seizures, altered dentate gyrus plasticity, and memory deficits. ( Ceolin, L; Fagni, L; Gangarossa, G; Lerner-Natoli, M; Paucard, A; Perroy, J; Valjent, E, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gangarossa, G | 1 |
| Ceolin, L | 1 |
| Paucard, A | 1 |
| Lerner-Natoli, M | 1 |
| Perroy, J | 1 |
| Fagni, L | 1 |
| Valjent, E | 1 |
1 other study available for sk&f 81297 and Seizures
| Article | Year |
|---|---|
Repeated stimulation of dopamine D1-like receptor and hyperactivation of mTOR signaling lead to generalized seizures, altered dentate gyrus plasticity, and memory deficits.
Topics: Animals; Benzazepines; Cerebral Cortex; Dentate Gyrus; Dopamine Agonists; Excitatory Postsynaptic Po | 2014 |