sk&f 81297 has been researched along with Parkinson Disease in 3 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dupre, KB | 1 |
| Eskow, KL | 1 |
| Barnum, CJ | 1 |
| Bishop, C | 1 |
| Vermeulen, RJ | 1 |
| Drukarch, B | 1 |
| Sahadat, MC | 1 |
| Goosen, C | 1 |
| Wolters, EC | 1 |
| Stoof, JC | 1 |
| Ekesbo, A | 1 |
| Andrén, PE | 1 |
| Gunne, LM | 1 |
| Sonesson, C | 1 |
| Tedroff, J | 1 |
3 other studies available for sk&f 81297 and Parkinson Disease
| Article | Year |
|---|---|
Striatal 5-HT1A receptor stimulation reduces D1 receptor-induced dyskinesia and improves movement in the hemiparkinsonian rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Agents; Animals; Benzazepines; Biogenic Monoamine | 2008 |
The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys.
Topics: Analysis of Variance; Animals; Benzazepines; Disease Models, Animal; Dopamine Agents; Ergolines; Mac | 1993 |
Motor effects of (-)-OSU6162 in primates with unilateral 6-hydroxydopamine lesions.
Topics: Adamantane; Animals; Apomorphine; Benzazepines; Benzopyrans; Callithrix; Dopamine Antagonists; Dose- | 2000 |