Page last updated: 2024-10-21

sk&f-38393 and Tourette Syndrome

sk&f-38393 has been researched along with Tourette Syndrome in 2 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taylor, JL1
Rajbhandari, AK1
Berridge, KC1
Aldridge, JW1
Braun, A1
Mouradian, MM1
Mohr, E1
Fabbrini, G1
Chase, TN1

Trials

1 trial available for sk&f-38393 and Tourette Syndrome

ArticleYear
Selective D-1 dopamine receptor agonist effects in hyperkinetic extrapyramidal disorders.
    Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adult; Aged; Basal Ganglia Diseases; Ben

1989

Other Studies

1 other study available for sk&f-38393 and Tourette Syndrome

ArticleYear
Dopamine receptor modulation of repetitive grooming actions in the rat: potential relevance for Tourette syndrome.
    Brain research, 2010, Mar-31, Volume: 1322

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines;

2010