sk&f-38393 has been researched along with Schizophrenia in 14 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, H | 1 |
| Zhu, L | 1 |
| Yang, H | 2 |
| Qian, W | 1 |
| Guo, L | 1 |
| Zhou, S | 1 |
| Gao, B | 1 |
| Li, Z | 1 |
| Zhou, Y | 1 |
| Jiang, H | 1 |
| Chen, K | 1 |
| Zhen, X | 1 |
| Liu, H | 1 |
| Issy, AC | 1 |
| Pedrazzi, JFC | 1 |
| van Oosten, ABS | 1 |
| Checheto, T | 1 |
| Silva, RR | 1 |
| Noël, F | 1 |
| Del-Bel, E | 1 |
| Grottick, AJ | 1 |
| MacQueen, DL | 1 |
| Barnes, SA | 1 |
| Carroll, C | 1 |
| Sanabria, EK | 1 |
| Bobba, V | 1 |
| Young, JW | 1 |
| Managò, F | 1 |
| Mereu, M | 1 |
| Mastwal, S | 1 |
| Mastrogiacomo, R | 1 |
| Scheggia, D | 1 |
| Emanuele, M | 1 |
| De Luca, MA | 1 |
| Weinberger, DR | 1 |
| Wang, KH | 1 |
| Papaleo, F | 1 |
| Zhang, L | 1 |
| Zhao, H | 1 |
| Zhao, C | 1 |
| Tseng, KY | 1 |
| Lewis, BL | 1 |
| Lipska, BK | 1 |
| O'Donnell, P | 1 |
| Ferrer, B | 1 |
| Gorriti, MA | 1 |
| Palomino, A | 1 |
| Gornemann, I | 1 |
| de Diego, Y | 1 |
| Bermudez-Silva, FJ | 1 |
| Bilbao, A | 1 |
| Fernandez-Espejo, E | 1 |
| Moratalla, R | 1 |
| Navarro, M | 1 |
| Rodríguez de Fonseca, F | 1 |
| Mittleman, G | 1 |
| LeDuc, PA | 1 |
| Whishaw, IQ | 1 |
| Mamelak, M | 1 |
| Chiu, S | 1 |
| Mishra, RK | 1 |
| Rodríguez-Puertas, R | 1 |
| Herrera-Marschitz, M | 1 |
| Koistinaho, J | 1 |
| Hökfelt, T | 1 |
| Boksa, P | 1 |
| Zhang, Y | 1 |
| Bestawros, A | 1 |
| Peng, RY | 1 |
| Mansbach, RS | 1 |
| Braff, DL | 1 |
| Geyer, MA | 1 |
| Davidson, M | 1 |
| Harvey, PD | 1 |
| Bergman, RL | 1 |
| Powchik, P | 1 |
| Kaminsky, R | 1 |
| Losonczy, MF | 1 |
| Davis, KL | 1 |
| Marmor, MF | 1 |
| Hock, P | 1 |
| Schechter, G | 1 |
| Pfefferbaum, A | 1 |
| Berger, PA | 1 |
| Maurice, R | 1 |
1 trial available for sk&f-38393 and Schizophrenia
| Article | Year |
|---|---|
Effects of the D-1 agonist SKF-38393 combined with haloperidol in schizophrenic patients.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adult; Clinical Trials as Topic; Drug Th | 1990 |
13 other studies available for sk&f-38393 and Schizophrenia
| Article | Year |
|---|---|
Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile.
Topics: Animals; Antipsychotic Agents; Berberine; Berberine Alkaloids; CHO Cells; Cricetinae; Cricetulus; Do | 2013 |
Effects of Doxycycline in Swiss Mice Predictive Models of Schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Anti-Bacterial Age | 2020 |
Convergent observations of MK-801-induced impairment in rat 5C-CPT performance across laboratories: reversal with a D
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Attention; Cognition; Dizocilpi | 2021 |
Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Cognitive Dysfunct | 2016 |
Calcium-related signaling pathways contributed to dopamine-induced cortical neuron apoptosis.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apoptosis; Atrophy; Calcium Sig | 2011 |
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazo | 2007 |
Cannabinoid CB1 receptor antagonism markedly increases dopamine receptor-mediated stereotypies.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Dopamine Agon | 2007 |
The role of D1 and D2 receptors in the heightened locomotion induced by direct and indirect dopamine agonists in rats with hippocampal damage: an animal analogue of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Arousal; Brain Map | 1993 |
High- and low-affinity states of dopamine D1 receptors in schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Benzazepines; Binding, Competitive; Brai | 1993 |
Dopamine D1 receptor modulation of glutamate receptor messenger RNA levels in the neocortex and neostriatum of unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine; Dopa | 1999 |
Dopamine D1 receptor changes due to caesarean section birth: effects of anesthesia, developmental time course, and functional consequences.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamines; Anesthetics, Inhalation; A | 2002 |
A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Implications for dopaminergic abnormalities in schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acoustic Stimulation; Animals; Disease M | 1990 |
Oscillatory potentials as a marker for dopaminergic disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dark Adaptation; | 1988 |