sk&f-38393 has been researched along with Morphine Dependence in 6 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In morphine-treated neurons, the number of inhibitory G-proteins (G alpha i) appeared to be slightly reduced (by about 16%)." | 1.29 | Adaptive changes in the number of Gs- and Gi-proteins underlie adenylyl cyclase sensitization in morphine-treated rat striatal neurons. ( Mulder, AH; Schoffelmeer, AN; Van Rijswijk, AL; Van Vliet, BJ; Wardeh, G, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dizgah, IM | 1 |
| Karimian, SM | 1 |
| Zarrindast, MR | 1 |
| Sohanaki, H | 1 |
| Saurer, TB | 1 |
| Ijames, SG | 1 |
| Lysle, DT | 1 |
| Van Vliet, BJ | 1 |
| Van Rijswijk, AL | 1 |
| Wardeh, G | 1 |
| Mulder, AH | 1 |
| Schoffelmeer, AN | 1 |
| Fiorillo, CD | 1 |
| Williams, JT | 1 |
| Bonci, A | 1 |
| Scheggi, S | 1 |
| Masi, F | 1 |
| Tagliamonte, A | 1 |
| Gambarana, C | 1 |
| Tolu, P | 1 |
| De Montis, MG | 1 |
| Bhargava, HN | 1 |
| Gulati, A | 1 |
6 other studies available for sk&f-38393 and Morphine Dependence
| Article | Year |
|---|---|
Attenuation of morphine withdrawal signs by a D1 receptor agonist in the locus coeruleus of rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; | 2005 |
Neuropeptide Y Y1 receptors mediate morphine-induced reductions of natural killer cell activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Anxiety Agents; Arginine; | 2006 |
Adaptive changes in the number of Gs- and Gi-proteins underlie adenylyl cyclase sensitization in morphine-treated rat striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Analysis of Variance; | 1993 |
D1-receptor regulation of synaptic potentials in the ventral tegmental area after chronic drug treatment.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Dopamine | 1998 |
Rats sensitized to morphine are resistant to the behavioral effects of an unavoidable stress.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dopamine Agonists | 2000 |
Modification of brain and spinal cord dopamine D1 receptors labeled with [3H]SCH 23390 after morphine withdrawal from tolerant and physically dependent rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Brain; Dopamine A | 1990 |