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sk&f-38393 and Intraocular Pressure

sk&f-38393 has been researched along with Intraocular Pressure in 4 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"Fenoldopam mesylate stimulates adenyl cyclase in porcine ocular trabecular meshwork and raises intraocular pressure in humans."9.07Intraocular pressure increases with fenoldopam, but not nitroprusside, in hypertensive humans. ( Elliott, WJ; Geanon, J; Karnezis, TA; Murphy, MB; Silverman, RA; Tripathi, RC, 1991)
"Fenoldopam mesylate stimulates adenyl cyclase in porcine ocular trabecular meshwork and raises intraocular pressure in humans."5.07Intraocular pressure increases with fenoldopam, but not nitroprusside, in hypertensive humans. ( Elliott, WJ; Geanon, J; Karnezis, TA; Murphy, MB; Silverman, RA; Tripathi, RC, 1991)
"Fenoldopam (FE), a dopamine DA1-receptor agonist, has been introduced for treatment of arterial hypertension and heart failure and for preservation of renal function."3.69Effects of fenoldopam on intracranial pressure and hemodynamic variables at normal and elevated intracranial pressure in anesthetized pigs. ( Hennes, HJ; Jantzen, JP, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reitsamer, HA1
Zawinka, C1
Branka, M1
Hennes, HJ1
Jantzen, JP1
PrĂ¼nte, C1
Nuttli, I1
Markstein, R1
Kohler, C1
Elliott, WJ1
Karnezis, TA1
Silverman, RA1
Geanon, J1
Tripathi, RC1
Murphy, MB1

Trials

1 trial available for sk&f-38393 and Intraocular Pressure

ArticleYear
Intraocular pressure increases with fenoldopam, but not nitroprusside, in hypertensive humans.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adult; Blood Pressure; Dose-Response Rel

1991

Other Studies

3 other studies available for sk&f-38393 and Intraocular Pressure

ArticleYear
Dopaminergic vasodilation in the choroidal circulation by d1/d5 receptor activation.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Blood Flow Veloci

2004
Effects of fenoldopam on intracranial pressure and hemodynamic variables at normal and elevated intracranial pressure in anesthetized pigs.
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia, General; Angiotensin II; Ani

1994
Effects of dopamine D-1 and D-2 receptors on intraocular pressure in conscious rabbits.
    Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:2-3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Aqueous Humor; Dopamine Agonist

1997