sk&f-38393 has been researched along with Hypothermia, Accidental in 5 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
| Excerpt | Relevance | Reference |
|---|---|---|
| "0 mg/kg, ip) hypothermia was reversed by the central and peripheral administration of the D2 antagonists S-(-)-sulpiride (3." | 3.68 | Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists. ( Michel, AD; Nunes, JL; Sharif, NA; Whiting, RL, 1991) |
| "The nonselective dopamine (DA) receptor agonists R(-)apomorphine (APO) and R(-)-N-n-propylnorapomorphine (NPA) elicited dose- and time-dependent hypothermia in mice with ED50 values of 300 and 18 micrograms/kg, respectively." | 3.67 | Hypothermia in mice: D2 dopamine receptor mediation and absence of spare receptors. ( Hizami, R; Kreuter, L; Meller, E, 1989) |
| "The hypothermia induced by apomorphine, a mixed dopamine (DA) agonist in male Swiss-Webster mice, was not blocked by the selective D-1 antagonist SCH 23390 but was completely blocked by the selective D-2 antagonists haloperidol, sulpiride and YM-09151-2." | 3.67 | Influence of D-1 receptor system on the D-2 receptor-mediated hypothermic response in mice. ( Fitten, J; Gordon, LI; Kodama, CK; Menon, MK, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gomeza, J | 1 |
| Zhang, L | 1 |
| Kostenis, E | 1 |
| Felder, C | 1 |
| Bymaster, F | 1 |
| Brodkin, J | 1 |
| Shannon, H | 1 |
| Xia, B | 1 |
| Deng, C | 1 |
| Wess, J | 1 |
| Nunes, JL | 1 |
| Sharif, NA | 1 |
| Michel, AD | 1 |
| Whiting, RL | 1 |
| Verma, A | 1 |
| Kulkarni, SK | 1 |
| Meller, E | 1 |
| Hizami, R | 1 |
| Kreuter, L | 1 |
| Menon, MK | 1 |
| Gordon, LI | 1 |
| Kodama, CK | 1 |
| Fitten, J | 1 |
5 other studies available for sk&f-38393 and Hypothermia, Accidental
| Article | Year |
|---|---|
Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesia; Animals; Apomorphine; Brain; | 1999 |
Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Body Temperature | 1991 |
Chronic electroconvulsive shock alters hypothermic response of B-HT 920 and SKF 38393 in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Azepines; Body Tem | 1991 |
Hypothermia in mice: D2 dopamine receptor mediation and absence of spare receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Antagonists; Animals; A | 1989 |
Influence of D-1 receptor system on the D-2 receptor-mediated hypothermic response in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Anxiety Agents; Apomorphin | 1988 |