sk&f-38393 has been researched along with Epilepsy in 6 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (83.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sharopov, S | 1 |
Moser, J | 1 |
Chen, R | 1 |
Kolbaev, SN | 1 |
Bernedo, VE | 1 |
Werhahn, KJ | 1 |
Luhmann, HJ | 1 |
Kilb, W | 1 |
Alam, AM | 1 |
Starr, MS | 2 |
Barone, P | 1 |
Morelli, M | 1 |
Cicarelli, G | 1 |
Cozzolino, A | 1 |
DeJoanna, G | 1 |
Campanella, G | 1 |
DiChiara, G | 1 |
Ushijima, I | 1 |
Kobayashi, T | 1 |
Suetsugi, M | 1 |
Watanabe, K | 1 |
Yamada, M | 1 |
Yamaguchi, K | 1 |
al-Tajir, G | 1 |
Chandler, CJ | 1 |
Starr, BS | 1 |
Smiałowski, A | 1 |
6 other studies available for sk&f-38393 and Epilepsy
Article | Year |
---|---|
Dopaminergic modulation of low-Mg²⁺-induced epileptiform activity in the intact hippocampus of the newborn mouse in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; | 2012 |
D1 agonists suppress zero Mg(2+)-induced epileptiform activity in the rat cingulate cortex slice.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Be | 1993 |
Expression of c-fos protein in the experimental epilepsy induced by pilocarpine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Brain; Dose-Respo | 1993 |
Cocaine: evidence for NMDA-, beta-carboline- and dopaminergic-mediated seizures in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzodiazepines; Brain Chemistr | 1998 |
Opposite effects of stimulation of D1 and D2 dopamine receptors on the expression of motor seizures in mouse and rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dopamine Agents; | 1990 |
Inhibition of low calcium induced epileptiform discharges in the hippocampus by dopamine D1 receptor agonist, SKF 38393.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Calcium; Electrop | 1990 |