sk&f-38393 has been researched along with Disease Models, Animal in 64 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of the dopamine D1 receptor agonist SKF 82958, the dopamine D1 receptor antagonist SCH 23390, the dopamine D2 receptor agonist sumanirole and the dopamine D2 receptor antagonist L741,626 on alcohol consumption and preference were assessed at different time points after treatment in subgroups of low and high alcohol drinking rats (LD and HD) using an intermittent alcohol access paradigm." | 3.83 | Dopamine receptor agonists modulate voluntary alcohol intake independently of individual levels of alcohol intake in rats. ( Baars, AM; Lesscher, HM; Rotte, MD; Spoelder, M; Vanderschuren, LJ, 2016) |
| "HCl), and that of imipramine in the behavioural despair model of depression." | 3.69 | Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression. ( Collu, M; D'Aquila, PS; Gessa, GL; Pani, L; Serra, G, 1994) |
| "The effect of SKF 38393 (1-phenyl-7,8-diol-2,3,4,5-tetrahydro-1H-3-benzazepine), a specific dopamine D1-receptor agonist, was studied on pylorus-ligation and water immersion plus restraint stress-induced gastric ulcers, and cysteamine-induced duodenal ulcers in rats." | 3.69 | Gastric and duodenal anti-ulcer activity of SKF 38393, a dopamine D1-receptor agonist in rats. ( Desai, JK; Goyal, RK; Parmar, NS, 1995) |
| " All rats separately underwent dose-response behavior testing for SKF38393 (0, 0." | 1.62 | Effects of intrastriatal injection of the dopamine receptor agonist SKF38393 and quinpirole on locomotor behavior in hemiparkinsonism rats. ( Chen, D; Guo, M; He, F; Jia, Q; Li, M; Li, Y; Sun, S; Sun, Y; Wang, M; Wang, X; Xiang, T; Yao, X; Zhang, X, 2021) |
| "We found that cataplexy is modulated by a D2-like receptor mechanism, whereas dopamine modulates sleep attacks by a D1-like receptor mechanism." | 1.36 | Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy. ( Burgess, CR; Gillis, L; Peever, JH; Tse, G, 2010) |
| "This "injection-conditioned catalepsy" was also observed after repeated treatment with the dopamine D2 antagonists, haloperidol and metoclopramide." | 1.30 | Conditioning to injection procedures and repeated testing increase SCH 23390-induced catalepsy in mice. ( Chinen, CC; Frussa-Filho, R, 1999) |
| "When bromocriptine was administered to ethanol-sensitized mice, it was ineffective in reducing voluntary ethanol abuse." | 1.29 | Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse. ( George, SR; Ng, GY, 1994) |
| " Moreover, long term administration of both imipramine or SKF 38393 down regulated D1 dopamine receptor number in the prefrontal cortex, while the association of the two drugs resulted in a receptor density similar to that of control rats." | 1.29 | Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine. ( Gambarana, C; Ghiglieri, O; Graziella de Montis, M, 1995) |
| "Haloperidol-induced VC were inhibited by the s." | 1.28 | Haloperidol-induced vacuous chewing in rats: suppression by alpha-methyl-tyrosine. ( Collu, M; Diana, M; Gessa, GL; Mura, A, 1992) |
| "Treatment with haloperidol (0." | 1.28 | Drug-induced purposeless chewing: animal model of dyskinesia or nausea? ( Iversen, SD; Rupniak, NM; Tye, SJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (4.69) | 18.7374 |
| 1990's | 16 (25.00) | 18.2507 |
| 2000's | 24 (37.50) | 29.6817 |
| 2010's | 17 (26.56) | 24.3611 |
| 2020's | 4 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Qin, J | 1 |
| Wei, T | 1 |
| Chen, H | 1 |
| Lin, X | 1 |
| Qin, D | 1 |
| Wei, F | 1 |
| Liu, P | 1 |
| Ye, W | 1 |
| Su, J | 1 |
| Cleal, M | 1 |
| Fontana, BD | 1 |
| Double, M | 1 |
| Mezabrovschi, R | 1 |
| Parcell, L | 1 |
| Redhead, E | 1 |
| Parker, MO | 1 |
| Guo, M | 1 |
| Xiang, T | 1 |
| Li, M | 1 |
| Sun, Y | 2 |
| Sun, S | 1 |
| Chen, D | 1 |
| Jia, Q | 1 |
| Li, Y | 1 |
| Yao, X | 1 |
| Wang, X | 1 |
| Zhang, X | 1 |
| He, F | 1 |
| Wang, M | 1 |
| Perreault, ML | 1 |
| Fan, T | 1 |
| Banasikowski, TJ | 1 |
| Grace, AA | 1 |
| George, SR | 2 |
| Zang, X | 1 |
| Cheng, ZY | 1 |
| Hua, N | 1 |
| Zhu, LH | 1 |
| He, L | 1 |
| Frau, L | 1 |
| Morelli, M | 3 |
| Simola, N | 2 |
| Hyacinthe, C | 1 |
| Barraud, Q | 1 |
| Tison, F | 1 |
| Bezard, E | 2 |
| Ghorayeb, I | 1 |
| Jiang, B | 1 |
| Wang, F | 2 |
| Yang, S | 1 |
| Fang, P | 1 |
| Deng, ZF | 1 |
| Xiao, JL | 1 |
| Hu, ZL | 1 |
| Chen, JG | 1 |
| Nomura, J | 1 |
| Jaaro-Peled, H | 1 |
| Lewis, E | 1 |
| Nuñez-Abades, P | 1 |
| Huppe-Gourgues, F | 1 |
| Cash-Padgett, T | 1 |
| Emiliani, F | 1 |
| Kondo, MA | 1 |
| Furuya, A | 1 |
| Landek-Salgado, MA | 1 |
| Ayhan, Y | 1 |
| Kamiya, A | 1 |
| Takumi, T | 1 |
| Huganir, R | 1 |
| Pletnikov, M | 1 |
| O'Donnell, P | 2 |
| Sawa, A | 1 |
| Chai, AP | 1 |
| Ma, WP | 1 |
| Wang, LP | 1 |
| Cao, J | 1 |
| Xu, L | 1 |
| Yang, YX | 1 |
| Mao, RR | 1 |
| Barnes, SA | 1 |
| Young, JW | 1 |
| Bate, ST | 1 |
| Neill, JC | 2 |
| Spoelder, M | 1 |
| Baars, AM | 1 |
| Rotte, MD | 1 |
| Vanderschuren, LJ | 1 |
| Lesscher, HM | 1 |
| Managò, F | 1 |
| Mereu, M | 1 |
| Mastwal, S | 1 |
| Mastrogiacomo, R | 1 |
| Scheggia, D | 1 |
| Emanuele, M | 1 |
| De Luca, MA | 1 |
| Weinberger, DR | 1 |
| Wang, KH | 1 |
| Papaleo, F | 1 |
| Giné, E | 1 |
| Echeverry-Alzate, V | 1 |
| Lopez-Moreno, JA | 1 |
| Rodriguez de Fonseca, F | 1 |
| Perez-Castillo, A | 1 |
| Santos, A | 1 |
| Di Chiara, G | 1 |
| Daniels, WM | 1 |
| Schallert, T | 1 |
| McLean, SL | 1 |
| Idris, NF | 1 |
| Woolley, ML | 1 |
| Ballion, B | 1 |
| Frenois, F | 1 |
| Zold, CL | 1 |
| Chetrit, J | 1 |
| Murer, MG | 1 |
| Gonon, F | 1 |
| Lindgren, HS | 1 |
| Ohlin, KE | 1 |
| Cenci, MA | 1 |
| Burgess, CR | 1 |
| Tse, G | 1 |
| Gillis, L | 1 |
| Peever, JH | 1 |
| Farrar, AM | 1 |
| Callahan, JW | 1 |
| Abercrombie, ED | 1 |
| Baamonde, C | 1 |
| Martínez-Cué, C | 1 |
| Flórez, J | 1 |
| Dierssen, M | 1 |
| Zarrindast, MR | 1 |
| Ardjmand, A | 1 |
| Ahmadi, S | 1 |
| Rezayof, A | 1 |
| Chugh, G | 1 |
| Lokhandwala, MF | 2 |
| Asghar, M | 1 |
| Geracitano, R | 1 |
| Paolucci, E | 1 |
| Prisco, S | 1 |
| Guatteo, E | 1 |
| Zona, C | 1 |
| Longone, P | 1 |
| Ammassari-Teule, M | 1 |
| Bernardi, G | 2 |
| Berretta, N | 1 |
| Mercuri, NB | 1 |
| Vorobyov, VV | 1 |
| Schibaev, NV | 1 |
| Carta, AR | 1 |
| Nanni, G | 1 |
| Scheggi, S | 1 |
| Leggio, B | 1 |
| Grappi, S | 1 |
| Masi, F | 1 |
| Rauggi, R | 1 |
| De Montis, MG | 1 |
| Yoshimura, N | 1 |
| Kuno, S | 1 |
| Chancellor, MB | 1 |
| De Groat, WC | 1 |
| Seki, S | 1 |
| Fujita, S | 1 |
| Okutsu, H | 1 |
| Yamaguchi, H | 1 |
| Nakamura, S | 1 |
| Adachi, K | 2 |
| Saigusa, T | 1 |
| Koshikawa, N | 2 |
| Aubert, I | 1 |
| Guigoni, C | 1 |
| Håkansson, K | 1 |
| Li, Q | 1 |
| Dovero, S | 1 |
| Barthe, N | 1 |
| Bioulac, BH | 1 |
| Gross, CE | 1 |
| Fisone, G | 1 |
| Bloch, B | 1 |
| Goldberg, MS | 1 |
| Pisani, A | 1 |
| Haburcak, M | 1 |
| Vortherms, TA | 1 |
| Kitada, T | 1 |
| Costa, C | 1 |
| Tong, Y | 1 |
| Martella, G | 1 |
| Tscherter, A | 1 |
| Martins, A | 1 |
| Roth, BL | 1 |
| Pothos, EN | 1 |
| Calabresi, P | 1 |
| Shen, J | 1 |
| Banday, AA | 1 |
| Marwaha, A | 1 |
| Tallam, LS | 1 |
| Rosengarten, H | 2 |
| Bartoszyk, GD | 1 |
| Quartermain, D | 1 |
| Lin, Y | 1 |
| Kachroo, A | 1 |
| Orlando, LR | 1 |
| Grandy, DK | 1 |
| Chen, JF | 1 |
| Young, AB | 1 |
| Schwarzschild, MA | 1 |
| Saurer, TB | 1 |
| Ijames, SG | 1 |
| Lysle, DT | 1 |
| Tseng, KY | 1 |
| Lewis, BL | 1 |
| Lipska, BK | 1 |
| Zhang, H | 1 |
| Ma, L | 1 |
| Chen, J | 1 |
| Zhen, X | 1 |
| Gershanik, O | 1 |
| Heikkila, RE | 1 |
| Duvoisin, RC | 1 |
| Olsson, M | 1 |
| Nikkhah, G | 1 |
| Bentlage, C | 1 |
| Björklund, A | 1 |
| D'Aquila, PS | 1 |
| Collu, M | 2 |
| Pani, L | 1 |
| Gessa, GL | 2 |
| Serra, G | 1 |
| Ng, GY | 1 |
| Mittleman, G | 1 |
| LeDuc, PA | 1 |
| Whishaw, IQ | 1 |
| Gambarana, C | 1 |
| Ghiglieri, O | 1 |
| Graziella de Montis, M | 1 |
| Desai, JK | 1 |
| Goyal, RK | 1 |
| Parmar, NS | 1 |
| Kashihara, K | 1 |
| Akiyama, K | 1 |
| Ishihara, T | 1 |
| Shiro, Y | 1 |
| Shohmori, T | 1 |
| Brooks, S | 1 |
| Kaur, S | 1 |
| Starr, BS | 1 |
| Starr, MS | 1 |
| George, B | 1 |
| Kulkarni, SK | 2 |
| Borowski, TB | 1 |
| Kokkinidis, L | 1 |
| Chinen, CC | 1 |
| Frussa-Filho, R | 1 |
| Ikeda, H | 1 |
| Hasegawa, M | 1 |
| Sato, M | 1 |
| Hirose, N | 1 |
| Cools, AR | 1 |
| Van Kampen, JM | 1 |
| Stoessl, AJ | 1 |
| Hayakawa, T | 1 |
| Chang, MC | 1 |
| Rapoport, SI | 1 |
| Appel, NM | 1 |
| Naidu, PS | 1 |
| Takamori, K | 1 |
| Yoshida, S | 1 |
| Okuyama, S | 1 |
| Van De Witte, SV | 1 |
| Groenewegen, HJ | 1 |
| Voorn, P | 1 |
| Pendleton, RG | 1 |
| Parvez, F | 1 |
| Sayed, M | 1 |
| Hillman, R | 1 |
| Joel, D | 1 |
| Avisar, A | 1 |
| Doljansky, J | 1 |
| Diana, M | 1 |
| Mura, A | 1 |
| Jinnah, HA | 1 |
| Langlais, PJ | 1 |
| Friedmann, T | 1 |
| Rupniak, NM | 1 |
| Tye, SJ | 1 |
| Iversen, SD | 1 |
| Peng, RY | 1 |
| Mansbach, RS | 1 |
| Braff, DL | 1 |
| Geyer, MA | 1 |
| Schweitzer, JW | 1 |
| Egawa, M | 1 |
| Friedhoff, AJ | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
1 review available for sk&f-38393 and Disease Models, Animal
| Article | Year |
|---|---|
The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzaze | 1986 |
63 other studies available for sk&f-38393 and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Salicylate Induced GABAAR Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cells, Cultured; | 2021 |
Dopaminergic modulation of working memory and cognitive flexibility in a zebrafish model of aging-related cognitive decline.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adolescent; Adult; Aged; Aged, 80 and ov | 2021 |
Effects of intrastriatal injection of the dopamine receptor agonist SKF38393 and quinpirole on locomotor behavior in hemiparkinsonism rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Disease Models | 2021 |
The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cognitive Dysfunction; Disease | 2017 |
The ameliorative effects and underlying mechanisms of dopamine D1-like receptor agonist SKF38393 on Aβ
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amyloid beta-Peptides; Amyloid Precursor | 2018 |
Performance of movement in hemiparkinsonian rats influences the modifications induced by dopamine agonists in striatal efferent dynorphinergic neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Analysis of Variance; | 2013 |
D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Disease M | 2014 |
SKF83959 produces antidepressant effects in a chronic social defeat stress model of depression through BDNF-TrkB pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Behavior | 2014 |
Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Age Factors; Animals; | 2016 |
Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Chronic Disease; | 2015 |
Dopamine D1 receptor activation improves PCP-induced performance disruption in the 5C-CPT by reducing inappropriate responding.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Attention; Disease Models, Anim | 2016 |
Dopamine receptor agonists modulate voluntary alcohol intake independently of individual levels of alcohol intake in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alcohol Drinking; Analysis of Variance; | 2016 |
Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Cognitive Dysfunct | 2016 |
The CB1 receptor is required for the establishment of the hyperlocomotor phenotype in developmentally-induced hypothyroidism in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain; Cannabinoid Receptor Ago | 2017 |
Priming of rotational behavior by a dopamine receptor agonist in Hemiparkinsonian rats: movement-dependent induction.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphi | 2009 |
D(1)-like receptor activation improves PCP-induced cognitive deficits in animal models: Implications for mechanisms of improved cognitive function in schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Avoidance Learning; Behavior, A | 2009 |
D2 receptor stimulation, but not D1, restores striatal equilibrium in a rat model of Parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Antiparkinso | 2009 |
Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aminoacetonitrile; Animals; Antiparkinso | 2009 |
Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Analysis of Variance; Anima | 2010 |
Reduced striatal acetylcholine efflux in the R6/2 mouse model of Huntington's disease: an examination of the role of altered inhibitory and excitatory mechanisms.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Bicuculline; Cho | 2011 |
G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Adrenergic be | 2011 |
Activation of dopamine D1 receptors in the medial septum improves scopolamine-induced amnesia in the dorsal hippocampus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amnesia; Analysis of Variance; Animals; | 2012 |
Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Binding Sites; Cyclic N- | 2012 |
Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY(93)-->ALA) mutation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Alanine; Animals; Avo | 2003 |
EEG modifications in the cortex and striatum after dopaminergic priming in the 6-hydroxydopamine rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Apomorphine; | 2003 |
Acquisition of an appetitive behavior prevents development of stress-induced neurochemical modifications in rat nucleus accumbens.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Analysis of Variance; | 2003 |
Dopaminergic mechanisms underlying bladder hyperactivity in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzopyrans; Disease Models, An | 2003 |
Altered pre- and postsynaptic dopamine receptor functions in spontaneously hypertensive rat: an animal model of attention-deficit hyperactivity disorder.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Attention | 2003 |
Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzaze | 2005 |
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Age Factors; Animals; Behavior, Animal; | 2005 |
Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Blood Glucose; Cyclic N-Oxides; | 2005 |
The effect of chronic administration of sarizotan, 5-HT1A agonist/D3/D4 ligand, on haloperidol-induced repetitive jaw movements in rat model of tardive dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Behavior, | 2006 |
Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Animals, | 2005 |
Neuropeptide Y Y1 receptors mediate morphine-induced reductions of natural killer cell activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Anxiety Agents; Arginine; | 2006 |
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazo | 2007 |
Chronic SKF83959 induced less severe dyskinesia and attenuated L-DOPA-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Disease M | 2007 |
Behavioral correlations of dopamine receptor activation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Disease Models, A | 1983 |
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphi | 1995 |
Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Antidepre | 1994 |
Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alcoholism; Animals; Blotting, Northern; | 1994 |
The role of D1 and D2 receptors in the heightened locomotion induced by direct and indirect dopamine agonists in rats with hippocampal damage: an animal analogue of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Arousal; Brain Map | 1993 |
Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clomipramine; Depression; Disea | 1995 |
Gastric and duodenal anti-ulcer activity of SKF 38393, a dopamine D1-receptor agonist in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Ulcer Agents; Cysteamine; | 1995 |
Levodopoa but not bromocriptine induces AP-1 and creb DNA-binding activity in the dopamine-depleted striatum of the rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Base Sequ | 1996 |
Motor actions of eliprodil in the normal and monoamine-depleted mouse: a role in the treatment of Parkinson's disease?
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Biogenic Mono | 1996 |
Dopaminergic modulation of lithium/pilocarpine-induced status epilepticus in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Disease | 1997 |
The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acoustic Stimulation; Analysis of Varian | 1998 |
Conditioning to injection procedures and repeated testing increase SCH 23390-induced catalepsy in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; | 1999 |
Effects of chronic haloperidol and clozapine on vacuous chewing and dopamine-mediated jaw movements in rats: evaluation of a revised animal model of tardive dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; | 1999 |
Dopamine D(1A) receptor function in a rodent model of tardive dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Behavior, | 2000 |
Selective dopamine receptor stimulation differentially affects [3H]arachidonic acid incorporation, a surrogate marker for phospholipase A2-mediated neurotransmitter signal transduction, in a rodent model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Arachidonic Acid; Biomarkers; D | 2001 |
Differential role of dopamine D1 and D2 receptors in isoniazid-induced vacuous chewing movements.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anticonvulsants; Antipsychotic | 2000 |
Repeated treatment with imipramine, fluvoxamine and tranylcypromine decreases the number of escape failures by activating dopaminergic systems in a rat learned helplessness test.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Benzazep | 2001 |
MK-801 alters the effects of priming with L-DOPA on dopamine D1 receptor-induced changes in neuropeptide mRNA levels in the rat striatal output neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Disease Models, Animal; Dizocil | 2002 |
Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; alpha-Synuclein; A | 2002 |
Enhancement of excessive lever-pressing after post-training signal attenuation in rats by repeated administration of the D1 antagonist SCH 23390 or the D2 agonist quinpirole, but not the D1 agonist SKF 38393 or the D2 antagonist haloperidol.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Disease Models, A | 2001 |
Haloperidol-induced vacuous chewing in rats: suppression by alpha-methyl-tyrosine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; Animals; Antipsych | 1992 |
Functional analysis of brain dopamine systems in a genetic mouse model of Lesch-Nyhan syndrome.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamines; Animals; Apomorphine; Brai | 1992 |
Drug-induced purposeless chewing: animal model of dyskinesia or nausea?
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Disease M | 1990 |
A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Implications for dopaminergic abnormalities in schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acoustic Stimulation; Animals; Disease M | 1990 |
Diminished D2 dopamine receptor function and the emergence of repetitive jaw movements.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Disease Models, A | 1988 |