Page last updated: 2024-10-21

sk&f-38393 and Cognitive Decline

sk&f-38393 has been researched along with Cognitive Decline in 6 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Research Excerpts

ExcerptRelevanceReference
"The heroin-evoked increase in premature responses is mimicked by a D1 agonist and prevented by a D1 antagonist or genetic ablation of the D1 receptor gene."1.46Dopamine D1 and D3 Receptors Modulate Heroin-Induced Cognitive Impairment through Opponent Actions in Mice. ( Lai, J; Li, Y; Qiao, X; Wang, Y; Wei, S; Yan, P; Yin, F; Zhang, H; Zhu, Y, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Cleal, M1
Fontana, BD1
Double, M1
Mezabrovschi, R1
Parcell, L1
Redhead, E1
Parker, MO1
Perreault, ML1
Fan, T1
Banasikowski, TJ1
Grace, AA1
George, SR1
Zang, X1
Cheng, ZY1
Sun, Y1
Hua, N1
Zhu, LH1
He, L1
Pekcec, A1
Schülert, N1
Stierstorfer, B1
Deiana, S1
Dorner-Ciossek, C1
Rosenbrock, H1
Managò, F1
Mereu, M1
Mastwal, S1
Mastrogiacomo, R1
Scheggia, D1
Emanuele, M1
De Luca, MA1
Weinberger, DR1
Wang, KH1
Papaleo, F1
Zhu, Y1
Wang, Y1
Lai, J1
Wei, S1
Zhang, H1
Yan, P1
Li, Y1
Qiao, X1
Yin, F1

Other Studies

6 other studies available for sk&f-38393 and Cognitive Decline

ArticleYear
Dopaminergic modulation of working memory and cognitive flexibility in a zebrafish model of aging-related cognitive decline.
    Neurobiology of aging, 2021, Volume: 102

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adolescent; Adult; Aged; Aged, 80 and ov

2021
The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction.
    The European journal of neuroscience, 2017, Volume: 46, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cognitive Dysfunction; Disease

2017
The ameliorative effects and underlying mechanisms of dopamine D1-like receptor agonist SKF38393 on Aβ
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, Feb-02, Volume: 81

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amyloid beta-Peptides; Amyloid Precursor

2018
Targeting the dopamine D
    British journal of pharmacology, 2018, Volume: 175, Issue:14

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain; Cognition; Cognitive Dys

2018
Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia.
    Cell reports, 2016, 08-23, Volume: 16, Issue:8

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Cognitive Dysfunct

2016
Dopamine D1 and D3 Receptors Modulate Heroin-Induced Cognitive Impairment through Opponent Actions in Mice.
    The international journal of neuropsychopharmacology, 2017, 03-01, Volume: 20, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antibodies; Benzazepines; Benzo

2017