sk&f-38393 has been researched along with Cocaine Abuse in 6 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results suggest that D(1-like) and D(2-like) agonists produce qualitatively different effects on cocaine self-administration that may influence their usefulness for the treatment of cocaine abuse and dependence." | 3.70 | Effects of dopamine D(1-like) and D(2-like) agonists on cocaine self-administration in rhesus monkeys: rapid assessment of cocaine dose-effect functions. ( Caine, SB; Mello, NK; Negus, SS, 2000) |
| " An increase in dosage to 3." | 1.31 | Effects of chronic administration of the D1 receptor partial agonist SKF 77434 on cocaine self-administration in rhesus monkeys. ( Bergman, J; Mutschler, NH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cannella, N | 1 |
| Oliveira, AMM | 1 |
| Hemstedt, T | 1 |
| Lissek, T | 1 |
| Buechler, E | 1 |
| Bading, H | 1 |
| Spanagel, R | 1 |
| Ortinski, PI | 1 |
| Turner, JR | 1 |
| Pierce, RC | 1 |
| Brenhouse, HC | 1 |
| Sonntag, KC | 1 |
| Andersen, SL | 1 |
| Zhang, XF | 1 |
| Hu, XT | 1 |
| White, FJ | 1 |
| Caine, SB | 1 |
| Negus, SS | 1 |
| Mello, NK | 1 |
| Mutschler, NH | 1 |
| Bergman, J | 1 |
6 other studies available for sk&f-38393 and Cocaine Abuse
| Article | Year |
|---|---|
Dnmt3a2 in the Nucleus Accumbens Shell Is Required for Reinstatement of Cocaine Seeking.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Cocaine- | 2018 |
Extrasynaptic targeting of NMDA receptors following D1 dopamine receptor activation and cocaine self-administration.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amino Acid Transport System X-AG; Animal | 2013 |
Transient D1 dopamine receptor expression on prefrontal cortex projection neurons: relationship to enhanced motivational salience of drug cues in adolescence.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Age Factors; Animals; Cocaine-Related Di | 2008 |
Whole-cell plasticity in cocaine withdrawal: reduced sodium currents in nucleus accumbens neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; | 1998 |
Effects of dopamine D(1-like) and D(2-like) agonists on cocaine self-administration in rhesus monkeys: rapid assessment of cocaine dose-effect functions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Cocaine- | 2000 |
Effects of chronic administration of the D1 receptor partial agonist SKF 77434 on cocaine self-administration in rhesus monkeys.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cocaine; Cocaine-Related Disord | 2002 |