sk&f-38393 has been researched along with Chronic Disease in 7 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " A daily levodopa dosage of at least 4 g appears to a prerequisite for long-term response to the drug." | 6.38 | Clinical relevance of long-term therapy with levodopa and orally active dopamine analogues in patients with chronic congestive heart failure. ( Hasenfuss, G; Just, H, 1989) |
| " A daily levodopa dosage of at least 4 g appears to a prerequisite for long-term response to the drug." | 2.38 | Clinical relevance of long-term therapy with levodopa and orally active dopamine analogues in patients with chronic congestive heart failure. ( Hasenfuss, G; Just, H, 1989) |
| "The reserpine-treated rats also exhibited stereotypy in response to acute injection of the D1-selective agonist SKF-38393 (10 mg/kg), which was not observed in control rats." | 1.28 | Neurochemical changes associated with the persistence of spontaneous oral dyskinesia in rats following chronic reserpine treatment. ( Lucki, I; McGonigle, P; Neisewander, JL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, XS | 1 |
| Chen, XM | 1 |
| Rong, F | 1 |
| Jing, T | 1 |
| Chen, S | 1 |
| Ma, WL | 1 |
| Jiang, B | 1 |
| Wang, F | 1 |
| Yang, S | 1 |
| Fang, P | 1 |
| Deng, ZF | 1 |
| Xiao, JL | 1 |
| Hu, ZL | 1 |
| Chen, JG | 1 |
| Chai, AP | 1 |
| Ma, WP | 1 |
| Wang, LP | 1 |
| Cao, J | 1 |
| Xu, L | 1 |
| Yang, YX | 1 |
| Mao, RR | 1 |
| Goldwater, DS | 1 |
| Pavlides, C | 1 |
| Hunter, RG | 1 |
| Bloss, EB | 1 |
| Hof, PR | 1 |
| McEwen, BS | 1 |
| Morrison, JH | 1 |
| Coffeen, U | 1 |
| López-Avila, A | 1 |
| Ortega-Legaspi, JM | 1 |
| del Angel, R | 1 |
| López-Muñoz, FJ | 1 |
| Pellicer, F | 1 |
| Neisewander, JL | 1 |
| Lucki, I | 1 |
| McGonigle, P | 1 |
| Hasenfuss, G | 1 |
| Just, H | 1 |
1 review available for sk&f-38393 and Chronic Disease
| Article | Year |
|---|---|
Clinical relevance of long-term therapy with levodopa and orally active dopamine analogues in patients with chronic congestive heart failure.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Chronic Disease; D | 1989 |
6 other studies available for sk&f-38393 and Chronic Disease
| Article | Year |
|---|---|
The regulation of SKF38393 on the dopamine and D1 receptor expression in hippocampus during chronic REM sleep restriction.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Chronic Disease; Cyclic AMP Res | 2013 |
SKF83959 produces antidepressant effects in a chronic social defeat stress model of depression through BDNF-TrkB pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Behavior | 2014 |
Chronic constant light-induced hippocampal late-phase long-term potentiation impairment in vitro is attenuated by antagonist of D1/D5 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Chronic Disease; | 2015 |
Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Chronic Disease; Dendrites; Den | 2009 |
Dopamine receptors in the anterior insular cortex modulate long-term nociception in the rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Afferent Pathways; Animals; Apomorphine; | 2008 |
Neurochemical changes associated with the persistence of spontaneous oral dyskinesia in rats following chronic reserpine treatment.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain; Caudat | 1991 |