Page last updated: 2024-10-21

sk&f-38393 and Brain Ischemia

sk&f-38393 has been researched along with Brain Ischemia in 3 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with pergolide significantly reduced this habituation impairment."1.32[Effects of D1 and D2 dopamine receptor agonists and antagonists on cerebral ischemia/reperfusion injury]. ( Lü, JN; Xu, T; Zeng, YM; Zong, XM, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zong, XM1
Zeng, YM1
Xu, T1
Lü, JN1
Yamamoto, Y1
Tanaka, T1
Shibata, S1
Watanabe, S1
O'Neill, MJ1
Hicks, CA1
Ward, MA1
Cardwell, GP1
Reymann, JM1
Allain, H1
Bentué-Ferrer, D1

Other Studies

3 other studies available for sk&f-38393 and Brain Ischemia

ArticleYear
[Effects of D1 and D2 dopamine receptor agonists and antagonists on cerebral ischemia/reperfusion injury].
    Sheng li xue bao : [Acta physiologica Sinica], 2003, Oct-25, Volume: 55, Issue:5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apoptosis; bcl-2-Associated X P

2003
Involvement of D1 dopamine receptor mechanism in ischemia-induced impairment of CA1 presynaptic fiber spikes in rat hippocampal slices.
    Brain research, 1994, Nov-28, Volume: 665, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Analysis of Variance;

1994
Dopamine D2 receptor agonists protect against ischaemia-induced hippocampal neurodegeneration in global cerebral ischaemia.
    European journal of pharmacology, 1998, Jul-03, Volume: 352, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Brain Ischemia; B

1998