Page last updated: 2024-10-21

sk&f-38393 and Body Weight

sk&f-38393 has been researched along with Body Weight in 11 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"The effects of chronic oral fenoldopam in the treatment of NYHA grade II-III heart failure secondary to ischaemic heart disease, were studied in a placebo controlled, double blind, randomised, parallel group fashion in 20 patients."5.06A preliminary study of the dopamine DA1 agonist fenoldopam in the treatment of chronic left ventricular failure due to ischaemic heart disease. ( Jeffrey, RF; Lee, MR; MacDonald, TM; Muir, AL, 1990)
" Then, the authors also examined the effect of subchronic treatment for 21 days with fluoxetine on clozapine-induced hyperphagia and modulation of body weight and fat pad weights."3.71Studies on modulation of feeding behavior by atypical antipsychotics in female mice. ( Kaur, G; Kulkarni, SK, 2002)
"In reserpine-pretreated mice, the dopamine (DA) agonist apomorphine, which stimulates both the D1 and D2 subtypes of DA receptors, increases body temperature according to a mechanism insensitive to the specific D2 DA antagonist sulpiride (Horowski 1978) or the preferential D2 DA antagonist haloperidol (Danielson, Coutts, Keashly and Tang 1985)."1.28Stimulation of central D1 dopamine receptors reverses reserpine-induced hypothermia in mice. ( Costentin, J; Duterte-Boucher, D; Michael-Titus, A; Panissaud, C, 1989)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's8 (72.73)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marwaha, A1
Lokhandwala, MF1
Terry, P1
Katz, JL1
Cincotta, AH1
Tozzo, E1
Scislowski, PW1
Waddington, JL1
Deveney, AM1
Clifford, J1
Tighe, O1
Croke, DT1
Sibley, DR1
Drago, J1
Nation, JR1
Miller, DK1
Kaur, G1
Kulkarni, SK1
Moody, CA1
Spear, LP1
Sloley, BD1
Trudeau, VL1
Dulka, JG1
Peter, RE1
MacDonald, TM1
Jeffrey, RF1
Muir, AL1
Lee, MR1
Brooks, DP1
Drutz, DJ1
Ruffolo, RR1
Duterte-Boucher, D1
Panissaud, C1
Michael-Titus, A1
Costentin, J1

Trials

1 trial available for sk&f-38393 and Body Weight

ArticleYear
A preliminary study of the dopamine DA1 agonist fenoldopam in the treatment of chronic left ventricular failure due to ischaemic heart disease.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aged; Body Weight; Coronary Disease; Dop

1990

Other Studies

10 other studies available for sk&f-38393 and Body Weight

ArticleYear
Tempol reduces oxidative stress and restores renal dopamine D1-like receptor- G protein coupling and function in hyperglycemic rats.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antioxidants; beta-Adrenergic R

2006
A comparison of the effects of the D1 receptor antagonists SCH 23390 and SCH 39166 on suppression of feeding behavior by the D1 agonist SKF38393.
    Psychopharmacology, 1994, Volume: 113, Issue:3-4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Body Weight; Dopa

1994
Bromocriptine/SKF38393 treatment ameliorates obesity and associated metabolic dysfunctions in obese (ob/ob) mice.
    Life sciences, 1997, Volume: 61, Issue:10

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Body Composition; Body Weight;

1997
Behavioral analysis of multiple D1-like dopamine receptor subtypes: new agents and studies in transgenic mice with D1A receptor knockout.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Body Weight;

1998
The effects of cadmium contamination on the discriminative stimulus properties of cocaine and related drugs.
    Experimental and clinical psychopharmacology, 1999, Volume: 7, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Body

1999
Studies on modulation of feeding behavior by atypical antipsychotics in female mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adipose Tissue; Animals; Antipsychotic A

2002
Ontogenetic differences in the psychopharmacological responses to separate and combined stimulation of D1 and D2 dopamine receptors during the neonatal to weanling age period.
    Psychopharmacology, 1992, Volume: 106, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Newborn; Behavi

1992
Selective depletion of dopamine in the goldfish pituitary caused by domperidone.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; Animals; Benzazepi

1991
Prevention and complete reversal of cyclosporine A-induced renal vasoconstriction and nephrotoxicity in the rat by fenoldopam.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Body Weight; Cyclosporins; Feno

1990
Stimulation of central D1 dopamine receptors reverses reserpine-induced hypothermia in mice.
    Neuropharmacology, 1989, Volume: 28, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Animals; Benzazepi

1989