Compounds > sk&f-38393
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sk&f-38393 and Anorexia

sk&f-38393 has been researched along with Anorexia in 2 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
"The concept of dopamine receptor subtypes and the recent development of selective dopamine receptor agonists and antagonists raises the possibility of specific subtype involvement in amphetamine-induced anorexia, and, furthermore, provides the means to evaluate the possibility."7.67Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats. ( Cooper, SJ; Gilbert, DB, 1985)
"The concept of dopamine receptor subtypes and the recent development of selective dopamine receptor agonists and antagonists raises the possibility of specific subtype involvement in amphetamine-induced anorexia, and, furthermore, provides the means to evaluate the possibility."3.67Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats. ( Cooper, SJ; Gilbert, DB, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ladurelle, N1
Duterte-Boucher, D1
Costentin, J1
Gilbert, DB1
Cooper, SJ1

Other Studies

2 other studies available for sk&f-38393 and Anorexia

ArticleYear
Stimulation of D1 and D2 dopamine receptors produces additive anorectic effects.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Anorexia;

1991
Analysis of dopamine D1 and D2 receptor involvement in d- and l-amphetamine-induced anorexia in rats.
    Brain research bulletin, 1985, Volume: 15, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Anorexia; Appetite

1985