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sk&f-38393 and Anochlesia

sk&f-38393 has been researched along with Anochlesia in 20 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Research Excerpts

ExcerptRelevanceReference
"By contrast, catalepsy induced by a single injection of haloperidol lasted only approximately 2 days, and tolerance developed to its effects after long-term treatment."1.30D2 dopamine antisense RNA expression vector, unlike haloperidol, produces long-term inhibition of D2 dopamine-mediated behaviors without causing Up-regulation of D2 dopamine receptors. ( Davidkova, G; Morabito, M; Weiss, B; Zhang, SP; Zhou, LW, 1998)
"This "injection-conditioned catalepsy" was also observed after repeated treatment with the dopamine D2 antagonists, haloperidol and metoclopramide."1.30Conditioning to injection procedures and repeated testing increase SCH 23390-induced catalepsy in mice. ( Chinen, CC; Frussa-Filho, R, 1999)
"Therefore, the THC-induced catalepsy model may be useful for distinguishing between both classes of NMDA receptor antagonists."1.29Competitive NMDA antagonists enhance the catalepsy induced by delta 9-tetrahydrocannabinol in mice. ( Hasegawa, T; Kameyama, T; Kinoshita, H; Nabeshima, T; Yamamoto, I, 1994)
"1."1.28Blockade of both D-1 and D-2 dopamine receptors may induce catalepsy in mice. ( Habibi-Moini, S; Zarrindast, MR, 1991)
"SCH 23390-induced catalepsy was potentiated by a large dose of the D-2 agonist, bromocriptine."1.27D-1 and D-2 receptor blockade have additive cataleptic effects in mice, but receptor effects may interact in opposite ways. ( Block, H; Klemm, WR, 1988)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's11 (55.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nowak, P2
Dabrowska, J1
Bortel, A1
Biedka, I1
Szczerbak, G1
Słomian, G1
Kostrzewa, RM2
Brus, R2
Arnt, J2
Hyttel, J1
Rodríguez de Fonseca, F1
Martín Calderón, JL1
Mechoulam, R1
Navarro, M1
Kinoshita, H1
Hasegawa, T1
Kameyama, T1
Yamamoto, I1
Nabeshima, T1
Rosenzweig-Lipson, S1
Bergman, J2
Bartoszyk, GD1
Harting, J1
Minck, KO1
Marin, C1
Engber, TM1
Chaudhuri, P1
Peppe, A1
Chase, TN1
Szkilnik, R1
Tidey, JW1
Davidkova, G1
Zhou, LW1
Morabito, M1
Zhang, SP1
Weiss, B1
Chinen, CC1
Frussa-Filho, R1
Platt, DM1
Rowlett, JK1
Spealman, RD1
Meyer, ME1
Cottrell, GA1
Van Hartesveldt, C1
Zarrindast, MR1
Habibi-Moini, S1
Andersen, PH1
Nielsen, EB1
Scheel-Krüger, J1
Jansen, JA1
Hohlweg, R1
Ogren, SO1
Fuxe, K1
Puglisi-Allegra, S1
Cabib, S1
Hess, EJ1
Albers, LJ1
Le, H1
Creese, I1
Klemm, WR1
Block, H1

Other Studies

20 other studies available for sk&f-38393 and Anochlesia

ArticleYear
Histamine H3 receptor agonist- and antagonist-evoked vacuous chewing movements in 6-OHDA-lesioned rats occurs in an absence of change in microdialysate dopamine levels.
    European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines;

2006
Differential inhibition by dopamine D-1 and D-2 antagonists of circling behaviour induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions.
    European journal of pharmacology, 1984, Jul-13, Volume: 102, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Antipsychotic Agen

1984
Repeated stimulation of D1 dopamine receptors enhances (-)-11-hydroxy-delta 8-tetrahydrocannabinol-dimethyl-heptyl-induced catalepsy in male rats.
    Neuroreport, 1994, Mar-21, Volume: 5, Issue:7

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Catalepsy; Dopamine Agents; Dro

1994
Competitive NMDA antagonists enhance the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
    Neuroscience letters, 1994, Jun-06, Volume: 174, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amantadine;

1994
Catalepsy-associated behavior induced by dopamine D1 receptor antagonists and partial dopamine D1 receptor agonists in squirrel monkeys.
    European journal of pharmacology, 1994, Aug-01, Volume: 260, Issue:2-3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Behavior,

1994
Roxindole: psychopharmacological profile of a dopamine D2 autoreceptor agonist.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Avoidance Learning

1996
Effects of kappa receptor agonists on D1 and D2 dopamine agonist and antagonist-induced behaviors.
    Psychopharmacology, 1996, Volume: 123, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidin

1996
Nitro-l-arginine attenuates SKF 38393-induced oral activity in neonatal 6-hydroxydopamine-lesioned rats.
    Acta neurobiologiae experimentalis, 1997, Volume: 57, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Catalepsy; Do

1997
Drug discrimination in methamphetamine-trained monkeys: agonist and antagonist effects of dopaminergic drugs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Benzazepines

1998
D2 dopamine antisense RNA expression vector, unlike haloperidol, produces long-term inhibition of D2 dopamine-mediated behaviors without causing Up-regulation of D2 dopamine receptors.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal;

1998
Conditioning to injection procedures and repeated testing increase SCH 23390-induced catalepsy in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines;

1999
Dissociation of cocaine-antagonist properties and motoric effects of the D1 receptor partial agonists SKF 83959 and SKF 77434.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Catalepsy; Cocain

2000
Dopamine D1 antagonists potentiate the durations of bar and cling catalepsy and the dorsal immobility response in rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines;

1992
Blockade of both D-1 and D-2 dopamine receptors may induce catalepsy in mice.
    General pharmacology, 1991, Volume: 22, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Catalepsy; Dopami

1991
Behavioural stimulation is induced by separate dopamine D-1 and D-2 receptor sites in reserpine-pretreated but not in normal rats.
    European journal of pharmacology, 1985, Jul-11, Volume: 113, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal;

1985
Thienopyridine derivatives identified as the first selective, full efficacy, dopamine D1 receptor agonists.
    European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Appetite Depressants; Benzazepi

1987
D1- and D2-receptor antagonists induce catalepsy via different efferent striatal pathways [corrected].
    Neuroscience letters, 1988, Mar-10, Volume: 85, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Catalepsy; Corpus

1988
The D2 dopamine receptor agonist LY171555 induces catalepsy in the mouse.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Appetite Depressants; Benzazepi

1988
Effects of chronic SCH23390 treatment on the biochemical and behavioral properties of D1 and D2 dopamine receptors: potentiated behavioral responses to a D2 dopamine agonist after selective D1 dopamine receptor upregulation.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Behavior, An

1986
D-1 and D-2 receptor blockade have additive cataleptic effects in mice, but receptor effects may interact in opposite ways.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Brom

1988