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sk&f-38393 and Anesthesia

sk&f-38393 has been researched along with Anesthesia in 9 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" These observed effects were not altered either by chloral hydrate anesthesia (in which glutamate-driven activity was studied) or by a more severe depletion of striatal DA levels (98% depletion produced by combined pretreatment with AMPT and reserpine)."3.68Microiontophoretic studies of the effects of D-1 and D-2 receptor agonists on type I caudate nucleus neurons: lack of synergistic interaction. ( Asdourian, D; Chiodo, LA; Shen, RY, 1992)
" SCH23390 (3-30 nmol), a selective D-1 DA receptor antagonist, caused a progressive parallel shift to the right in the dose-response curve for DA-induced pancreatic secretion without changes in the maximal response."1.29D-1 dopamine receptors mediate dopamine-induced pancreatic exocrine secretion in anesthetized dogs. ( Chiba, S; Horiuchi, A; Iwatsuki, K; Ren, LM, 1995)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's8 (88.89)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iwatsuki, K1
Horiuchi, A1
Ren, LM1
Chiba, S1
Adachi, K1
Ikeda, H1
Hasegawa, M1
Nakamura, S1
Waddington, JL1
Koshikawa, N1
Shen, RY1
Asdourian, D1
Chiodo, LA1
Clark, KL1
Robertson, MJ1
Drew, GM1
Pellissier, G1
Demenge, P1
Horita, A1
Carino, MA1
Nishimura, Y1
Brooks, DP1
DePalma, PD1
Cyronak, MJ1
Karpinski, K1
Weinstock, J1
Kontani, H1
Inoue, T1
Sakai, T1
Kopia, GA1
Valocik, RE1

Other Studies

9 other studies available for sk&f-38393 and Anesthesia

ArticleYear
D-1 dopamine receptors mediate dopamine-induced pancreatic exocrine secretion in anesthetized dogs.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1995, Volume: 18 Suppl 1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Benzazepines; Dogs;

1995
SK&F 83959 and non-cyclase-coupled dopamine D1-like receptors in jaw movements via dopamine D1-like/D2-like receptor synergism.
    European journal of pharmacology, 1999, Feb-19, Volume: 367, Issue:2-3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Anesthesia; Animals;

1999
Microiontophoretic studies of the effects of D-1 and D-2 receptor agonists on type I caudate nucleus neurons: lack of synergistic interaction.
    Synapse (New York, N.Y.), 1992, Volume: 11, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; Anesthesia; Animal

1992
Do renal tubular dopamine receptors mediate dopamine-induced diuresis in the anesthetized cat?
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Benzazepines; Cats;

1991
Hypotensive and bradycardic effects elicited by spinal dopamine receptor stimulation: effects of D1 and D2 receptor agonists and antagonists.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Antipsychotic Agent

1991
D1 agonist SKF 38393 antagonizes pentobarbital-induced narcosis and depression of hippocampal and cortical cholinergic activity in rats.
    Life sciences, 1991, Volume: 49, Issue:8

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Atropine; Atropine

1991
Pharmacology of SK&F R-105058 and R-106114, N-ethyl carbamate ester prodrugs of fenoldopam.
    Pharmacology, 1990, Volume: 41, Issue:5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Benzazepines; Biotr

1990
Dopamine receptor subtypes that induce hyperactive urinary bladder response in anesthetized rats.
    Japanese journal of pharmacology, 1990, Volume: 54, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Bromocriptine; Drug

1990
Demonstration of specific dopamine-1 receptor-mediated coronary vasodilation in the anesthetized dog.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Angina Pectoris; Animals; Be

1989