sk&f-38393 has been researched along with Alcoholism in 4 studies
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "When bromocriptine was administered to ethanol-sensitized mice, it was ineffective in reducing voluntary ethanol abuse." | 1.29 | Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse. ( George, SR; Ng, GY, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, J | 1 |
| Marty, VN | 1 |
| Mulpuri, Y | 1 |
| Olsen, RW | 1 |
| Spigelman, I | 1 |
| Ng, GY | 1 |
| George, SR | 1 |
| Cohen, C | 1 |
| Perrault, G | 1 |
| Sanger, DJ | 1 |
| Ikeda, H | 1 |
| Hatta, S | 1 |
| Ozawa, H | 1 |
| Ohshika, H | 1 |
| Saito, T | 1 |
4 other studies available for sk&f-38393 and Alcoholism
| Article | Year |
|---|---|
Selective modulation of GABAergic tonic current by dopamine in the nucleus accumbens of alcohol-dependent rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alcoholism; Animals; Dopamine; Dopamine | 2014 |
Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alcoholism; Animals; Blotting, Northern; | 1994 |
Effects of D1 dopamine receptor agonists on oral ethanol self-administration in rats: comparison with their efficacy to produce grooming and hyperactivity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Alcohol Drinking; | 1999 |
Effect of chronic ethanol treatment of Ca2+-inhibited adenylyl cyclase in mouse striatum.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclase Inhibitors; Alcoholism; | 1999 |