Page last updated: 2024-10-21

sk&f-38393 and Ache

sk&f-38393 has been researched along with Ache in 9 studies

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine: A selective D1 dopamine receptor agonist used primarily as a research tool.
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol : A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1 and two hydroxy substituents at positions 7 and 8.
SKF 38393 : A racemate comprising equimolar amounts of (R)- and (S)-SKF 38393

Research Excerpts

ExcerptRelevanceReference
"Using behavioral approaches in vivo, we found that D3KO animals exhibit reduced paw withdrawal latencies to thermal pain stimulation (Hargreaves' test) over wild type (WT) controls."1.38Increased excitability of spinal pain reflexes and altered frequency-dependent modulation in the dopamine D3-receptor knockout mouse. ( Baran, CA; Brewer, KL; Clemens, S; Keeler, BE, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fazzari, J1
Lin, H1
Murphy, C1
Ungard, R1
Singh, G1
Taniguchi, W1
Nakatsuka, T1
Miyazaki, N1
Yamada, H1
Takeda, D1
Fujita, T1
Kumamoto, E1
Yoshida, M1
Keeler, BE1
Baran, CA1
Brewer, KL1
Clemens, S1
Coffeen, U1
López-Avila, A1
Ortega-Legaspi, JM1
del Angel, R1
López-Muñoz, FJ1
Pellicer, F1
Magnusson, JE1
Fisher, K1
Gao, X1
Zhang, Y1
Wu, G2
Morgan, MJ1
Franklin, KB1
Jiang, JW1
Wu, GC1
Cao, XD1
Barasi, S1
Ben-Sreti, MM1
Clatworthy, AL1
Duggal, KN1
Gonzalez, JP1
Robertson, J1
Rooney, KF1
Sewell, RD1

Other Studies

9 other studies available for sk&f-38393 and Ache

ArticleYear
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain.
    Scientific reports, 2015, Feb-11, Volume: 5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Bone and Bones; Breast Neoplasms; Capsai

2015
In vivo patch-clamp analysis of dopaminergic antinociceptive actions on substantia gelatinosa neurons in the spinal cord.
    Pain, 2011, Volume: 152, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Ac

2011
Increased excitability of spinal pain reflexes and altered frequency-dependent modulation in the dopamine D3-receptor knockout mouse.
    Experimental neurology, 2012, Volume: 238, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesics; Animals; Animals, Newborn; B

2012
Dopamine receptors in the anterior insular cortex modulate long-term nociception in the rat.
    European journal of pain (London, England), 2008, Volume: 12, Issue:5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Afferent Pathways; Animals; Apomorphine;

2008
The involvement of dopamine in nociception: the role of D(1) and D(2) receptors in the dorsolateral striatum.
    Brain research, 2000, Feb-14, Volume: 855, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine; Dopa

2000
Effects of dopaminergic agents on carrageenan hyperalgesia in rats.
    European journal of pharmacology, 2000, Oct-06, Volume: 406, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Carrageenan; Dopa

2000
Dopamine receptor subtypes and formalin test analgesia.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesia; Animals; Apomorphine; Benzaze

1991
Effects of four dopamine agonists on l-tetrahydropalmatine-induced analgesia and electroacupuncture analgesia in rabbits.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acupuncture Analgesia; Alkaloids; Animal

1990
Dopamine receptor-mediated spinal antinociception in the normal and haloperidol pretreated rat: effects of sulpiride and SCH 23390.
    British journal of pharmacology, 1987, Volume: 90, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Benz

1987