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sk&f 105685 and Adjuvant Arthritis

sk&f 105685 has been researched along with Adjuvant Arthritis in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's5 (83.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badger, AM; Bradley, FC; Cheeseman, EN; DiMartino, MJ; Dorman, JW; Hanna, N; Mirabelli, CK; Picker, DH; Schwartz, DA1
Badger, AM; Bugelski, PJ; High, WB; Nichols, ME; Solleveld, HA; Swift, BA1
Albrightson, CR; Badger, AM; Best, C; Coffman, TM; Fan, PY; Howell, DN1
Badger, AM; Bugelski, PJ; Clark, RK; Griswold, DE; Swift, BA; Webb, EF1
Badger, AM; Bugelski, PJ; DiMartino, MJ; Greig, R; High, WB; Swift, BA1
Badger, AM; Dimartino, MJ; Dorman, JW; Hanna, N; Mirabelli, CK; Picker, DH; Schwartz, DA; Talmadge, JE1

Other Studies

6 other study(ies) available for sk&f 105685 and Adjuvant Arthritis

ArticleYear
Antiarthritic and suppressor cell inducing activity of azaspiranes: structure-function relationships of a novel class of immunomodulatory agents.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:11

    Topics: Animals; Arthritis, Experimental; Aza Compounds; Chemical Phenomena; Chemistry; Immunosuppressive Agents; Male; Molecular Structure; Organometallic Compounds; Rats; Rats, Inbred Lew; Spiro Compounds; Structure-Activity Relationship; T-Lymphocytes, Regulatory

1990
Effects of a novel azaspirane (SK&F 105685) on arthritic lesions in the adjuvant Lewis rat: attenuation of the inflammatory process and preservation of skeletal integrity.
    The Journal of rheumatology, 1994, Volume: 21, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bone and Bones; Cells, Cultured; Drug Evaluation, Preclinical; Edema; Immunosuppressive Agents; Inflammation; Lymphocyte Activation; Male; Microscopy, Electron, Scanning; Osteoclasts; Rats; Rats, Inbred Lew; Spiro Compounds; Spleen; T-Lymphocytes, Regulatory

1994
The azaspirane SKF 105685 ameliorates renal allograft rejection in rats.
    Journal of the American Society of Nephrology : JASN, 1993, Volume: 3, Issue:10

    Topics: Animals; Arthritis, Experimental; Drug Evaluation, Preclinical; Eicosanoids; Graft Rejection; Immunosuppressive Agents; Inflammation; Interleukin-1; Kidney Transplantation; Male; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Rats, Inbred Strains; Renal Circulation; Spiro Compounds; Transplantation, Homologous

1993
Beneficial effects of SK&F 105685 in rat adjuvant arthritis: prophylactic and therapeutic effects on disease parameter progression.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blood Cell Count; Edema; Eicosanoids; Male; Rats; Rats, Inbred Lew; Spiro Compounds; T-Lymphocytes, Regulatory

1993
The effect of SK&F 105685, a novel suppressor cell-inducing compound, in the adjuvant arthritic rat.
    British journal of rheumatology, 1991, Volume: 30 Suppl 2

    Topics: Administration, Oral; Animals; Arthritis, Experimental; Dose-Response Relationship, Drug; Mice; Rats; Rats, Inbred Lew; Spiro Compounds; T-Lymphocytes, Regulatory

1991
Inhibition of animal models of autoimmune disease and the induction of non-specific suppressor cells by SK&F 105685 and related azaspiranes.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Autoimmune Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Lymphoid Tissue; Male; Rats; Rats, Inbred Lew; Spiro Compounds; T-Lymphocytes, Regulatory

1989