Compounds > sivelestat
Page last updated: 2024-08-26

sivelestat and Pneumonia

sivelestat has been researched along with Pneumonia in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Hu, H; Liu, Y; Luo, M; Sun, Y; Wu, G; Zeng, Z; Zhao, X1
Chen, K; Feng, L; Guo, F; Huang, C; Li, Y; Liu, X; Wang, R; Wu, Y; Zhu, W1
Imamura, T; Inoue, S; Kawaguchi, M; Kishimoto, M; Matsui, H; Myojin, T; Noda, T; Yamana, H; Yasunaga, H1
Arimura-Omori, M; Hamada, N; Harada, E; Ikeda-Harada, C; Mikumo, H; Nakanishi, Y; Ogata-Suetsugu, S; Suzuki, K; Yanagihara, T; Yokoyama, T1
Churg, A; Ekholm, K; Falk-Håkansson, H; Gränse, M; Jungar, C; Kozma, V; Lal, H; Lindahl, M; Ottosson, T; Sanfridson, A; Stevens, T; Wright, JL1
Fukunaga, M; Iba, T; Kidokoro, A; Sugimotoa, K; Takuhiro, K; Yoshikawa, S1
Kondo, T; Niikawa, H; Oishi, H; Sugawara, T; Suzuki, S; Tabata, T1
Aoshiba, K; Kakuta, Y; Konno, K; Nagai, A; Ozawa, Y; Yasui, S1

Other Studies

8 other study(ies) available for sivelestat and Pneumonia

ArticleYear
[Sivelestat sodium for treatment of patients with COVID-19-associated acute respiratory distress syndrome in intensive care unit: a single-center retrospective cohort study].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023, Aug-20, Volume: 43, Issue:8

    Topics: C-Reactive Protein; COVID-19; Critical Illness; Humans; Intensive Care Units; Interleukin-6; Pneumonia; Procalcitonin; Retrospective Studies

2023
Inhibition of human neutrophil elastase by pentacyclic triterpenes.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Glycine; Humans; Kinetics; Leukocyte Elastase; Mice, Inbred BALB C; Molecular Docking Simulation; Pentacyclic Triterpenes; Pneumonia; Proton Magnetic Resonance Spectroscopy; Saponins; Smoking; Sulfonamides; Triterpenes; Ursolic Acid

2013
Sivelestat sodium and mortality in pneumonia patients requiring mechanical ventilation: propensity score analysis of a Japanese nationwide database.
    Journal of anesthesia, 2017, Volume: 31, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Databases, Factual; Female; Glycine; Humans; Japan; Male; Middle Aged; Pneumonia; Propensity Score; Respiration, Artificial; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides

2017
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib-naphthalene-induced acute pneumonitis in mice.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Female; Gefitinib; Glycine; Humans; Kaplan-Meier Estimate; Leukocyte Count; Leukocyte Elastase; Lung; Mice, Inbred C57BL; Naphthalenes; Neutrophils; Pneumonia; Quinazolines; Serine Proteinase Inhibitors; Sulfonamides; Weight Loss

2017
AZD9668: pharmacological characterization of a novel oral inhibitor of neutrophil elastase.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:1

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Dogs; Dose-Response Relationship, Drug; Emphysema; Female; Glycine; Guinea Pigs; Humans; Kinetics; Leukocyte Elastase; Mice; Mice, Inbred BALB C; Oxadiazoles; Pneumonia; Protein Binding; Pyridones; Pyrimidinones; Rats; Serine Proteinase Inhibitors; Species Specificity; Substrate Specificity; Sulfonamides; Sulfones; Swine; Tobacco Smoke Pollution

2011
Pretreatment of sivelestat sodium hydrate improves the lung microcirculation and alveolar damage in lipopolysaccharide-induced acute lung inflammation in hamsters.
    Shock (Augusta, Ga.), 2006, Volume: 26, Issue:1

    Topics: Acute Disease; Animals; Cricetinae; Glycine; Leukocyte Elastase; Lipopolysaccharides; Male; Microcirculation; Pneumonia; Pulmonary Alveoli; Pulmonary Circulation; Serine Proteinase Inhibitors; Sulfonamides

2006
Sivelestat reduces reperfusion injury of lungs harvested from endotoxin-primed rats by inhibition of neutrophil-mediated inflammation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2007, Volume: 26, Issue:4

    Topics: Animals; Cytokines; Endotoxins; Escherichia coli; Glycine; Injections, Intraperitoneal; Interleukin-8; Leukocyte Elastase; Lung; Lung Transplantation; Male; Neutrophils; Pneumonia; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfonamides; Tissue and Organ Harvesting; Tumor Necrosis Factor-alpha

2007
A specific neutrophil elastase inhibitor (ONO-5046.Na) attenuates LPS-induced acute lung inflammation in the hamster.
    The European respiratory journal, 1995, Volume: 8, Issue:8

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis, Leukocyte; Cricetinae; Glycine; Leukocyte Elastase; Lipopolysaccharides; Lung; Male; Mesocricetus; Neutrophils; Organ Size; Pancreatic Elastase; Pneumonia; Respiratory Distress Syndrome; Sulfonamides

1995