sivelestat has been researched along with Liver Diseases in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Harie, I; Ishida, Y; Ishigami, A; Kimura, A; Kondo, T; Kuninaka, Y; Mukaida, N; Nosaka, M; Zhang, S | 1 |
| Fujimura, T; Fushida, S; Hayashi, H; Kitagawa, H; Makino, I; Miyashita, T; Munesue, S; Nakagawara, H; Nakanuma, S; Ohta, T; Saito, H; Sakai, S; Tajima, H; Yamamoto, Y | 1 |
| Fukunaga, K; Kondo, T; Murata, S; Nakano, Y; Oda, T; Ohkohchi, N; Pak, S; Sasaki, R | 1 |
| Ishii, K; Ito, Y; Kakita, A; Katagiri, H; Majima, M; Matsumoto, Y | 1 |
| Kwon, AH; Qiu, Z | 1 |
| Iwasaki, Y; Kubota, K; Okada, T; Sawada, T; Shimoda, M | 1 |
| Ishihara, H; Kudoh, A; Kudoh, E; Matsuki, A | 1 |
7 other study(ies) available for sivelestat and Liver Diseases
| Article | Year |
|---|---|
Essential Involvement of Neutrophil Elastase in Acute Acetaminophen Hepatotoxicity Using BALB/c Mice.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Leukocyte Elastase; Liver Diseases; Mice; Mice, Inbred BALB C; Necrosis; Transaminases | 2023 |
Sivelestat sodium hydrate inhibits neutrophil migration to the vessel wall and suppresses hepatic ischemia-reperfusion injury.
Topics: Animals; Cell Adhesion; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycine; Immune System Diseases; Leukocyte Disorders; Liver Diseases; Male; Neutrophils; Rats; Rats, Wistar; Reperfusion Injury; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2014 |
Platelet adhesion in the sinusoid caused hepatic injury by neutrophils after hepatic ischemia reperfusion.
Topics: Animals; Blood Platelets; Cytokines; Glycine; Liver; Liver Circulation; Liver Diseases; Male; Neutrophils; Platelet Adhesiveness; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Serine Proteinase Inhibitors; Sulfonamides | 2010 |
Neutrophil elastase inhibitor attenuates lipopolysaccharide-induced hepatic microvascular dysfunction in mice.
Topics: Analysis of Variance; Animals; Benzoates; Cytokines; Disease Models, Animal; Drug Interactions; Glycine; Injections, Intravenous; Interleukin-1; Lipopolysaccharides; Liver Circulation; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Microcirculation; Microscopy; Probability; Pyrrolidines; Random Allocation; Reference Values; Sensitivity and Specificity; Sulfonamides; Treatment Outcome; Tumor Necrosis Factor-alpha | 2002 |
Neutrophil elastase inhibitor prevents endotoxin-induced liver injury following experimental partial hepatectomy.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endotoxins; Glycine; Hepatectomy; Humans; Leukocyte Elastase; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Sulfonamides | 2007 |
Protective effect of Sivelestat in a porcine hepatectomy model prepared using an intermittent Pringle method.
Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Cell Line; Enzyme Inhibitors; Glycine; Heart Rate; Hepatectomy; Hepatocytes; In Situ Nick-End Labeling; In Vitro Techniques; Leukocyte Elastase; Lipopolysaccharides; Liver Diseases; Nitric Oxide Synthase Type II; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Serine Proteinase Inhibitors; Sulfonamides; Swine; Tumor Necrosis Factor-alpha | 2008 |
ONO-5046, an elastase inhibitor, attenuates liver mitochondrial dysfunction after endotoxin.
Topics: Adenosine Diphosphate; Animals; Blood Pressure; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Escherichia coli; Glycine; Guinea Pigs; Ketone Bodies; Leukocyte Elastase; Lipopolysaccharides; Liver Diseases; Male; Mitochondria, Liver; Oxygen; Phosphorylation; Respiration; Serine Proteinase Inhibitors; Sulfonamides | 1998 |