sivelestat has been researched along with Injuries, Spinal Cord in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ban, E; Bonanomi, D; Choi, H; Han, I; Jo, MJ; Joshi, HP; Kim, A; Kim, KT; Kim, SB; Kumar, H; Lee, SH; Muttigi, M; Sohn, S; Zeng, X | 1 |
| Dong, HL; Huo, J; Ma, R; Su, BX; Zhu, XL | 1 |
| Goto, M; Higashi, A; Iguro, Y; Iwamoto, S; Sakata, R; Ueno, T | 1 |
| Muraguchi, M; Murata, K; Nishisho, T; Ohmoto, Y; Ohsaki, H; Shiba, K; Takeda, E; Taketani, Y; Tonai, T | 1 |
4 other study(ies) available for sivelestat and Injuries, Spinal Cord
| Article | Year |
|---|---|
Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury.
Topics: Angiopoietin-1; Angiopoietin-2; Animals; Cicatrix; Cytokines; Disease Models, Animal; Endothelial Cells; Female; Gene Expression Regulation; Glycine; Humans; Laminin; Leukocyte Elastase; Nerve Tissue Proteins; Nociceptin; Occludin; Opioid Peptides; Rats; Rats, Sprague-Dawley; Recovery of Function; Serine Proteinase Inhibitors; Spinal Cord Injuries; Sulfonamides; Transforming Growth Factor beta1; Zonula Occludens-1 Protein | 2018 |
GAPDH/Siah1 cascade is involved in traumatic spinal cord injury and could be attenuated by sivelestat sodium.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Disease Models, Animal; Drug Evaluation, Preclinical; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycine; Interleukin-1beta; Male; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; Nuclear Proteins; Random Allocation; Rats, Sprague-Dawley; Recovery of Function; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Sulfonamides; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases | 2016 |
Protective effect of sivelestat sodium hydrate (ONO-5046) on ischemic spinal cord injury.
Topics: Animals; Apoptosis; Disease Models, Animal; Glycine; Infusions, Intra-Arterial; Leukocyte Elastase; Motor Activity; Motor Neurons; Neuroprotective Agents; Paraplegia; Rabbits; Serine Proteinase Inhibitors; Spinal Cord Injuries; Spinal Cord Ischemia; Sulfonamides | 2009 |
A neutrophil elastase inhibitor (ONO-5046) reduces neurologic damage after spinal cord injury in rats.
Topics: Animals; Blood-Brain Barrier; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Gene Expression; Glycine; Growth Substances; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukocyte Elastase; Motor Activity; Peroxidase; Rats; Rats, Wistar; Recovery of Function; RNA, Messenger; Serine Proteinase Inhibitors; Spinal Cord; Spinal Cord Injuries; Sulfonamides | 2001 |