sivelestat has been researched along with Inflammatory Response Syndrome, Systemic in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (61.11) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, H; Baba, Y; Hirashima, K; Iwatsuki, M; Karashima, R; Kinoshita, K; Kurashige, J; Nagai, Y; Watanabe, M | 1 |
| Inoue, N; Itatani, K; Kitamura, T; Miyaji, K; Oka, N; Shibata, K; Tomoyasu, T | 1 |
| Fujimura, T; Fushida, S; Hayashi, H; Kitagawa, H; Makino, I; Miyashita, T; Munesue, S; Nakagawara, H; Nakanuma, S; Ohta, T; Saito, H; Sakai, S; Tajima, H; Yamamoto, Y | 1 |
| Huang, P; Li, QG; Xiao, XG; Zu, HG | 1 |
| Izumikawa, K; Kakeya, H; Kohno, S; Mukae, H; Nakamura, S; Seki, M; Tashiro, T; Yamamoto, Y; Yanagihara, K | 1 |
| Harada, N; Harimoto, N; Kakeji, Y; Koga, T; Maehara, Y; Miyazaki, M; Morita, M; Nagata, S; Oki, E; Saeki, H | 1 |
| Aikawa, N; Endo, S; Hirasawa, H; Ikeda, T; Ishizaka, A; Kawasaki, Y; Shimazaki, S; Shinozaki, M; Sugimoto, H; Taenaka, N; Yamamoto, Y | 1 |
| Inada, E; Iwanuma, Y; Kajiyama, Y; Kugimiya, T; Kumakura, S; Nagaoka, I; Sugasawa, Y; Takeuchi, K; Tsurumaru, M; Yamaguchi, K | 1 |
| Hagio, T; Kawabata, K; Matsuoka, S | 1 |
| Bellomo, R; Naka, T; Uchino, S; Wan, L | 1 |
| Abiru, T; Aikawa, N; Fujishima, S; Kobayashi, M; Matsuoka, S | 1 |
| Imabayashi, T; Kakihana, Y; Kanmura, Y; Matsunaga, A; Okayama, N; Omae, T; Setoguchi, D | 1 |
| Fujino, Y; Hata, H; Iwai, S; Matsuda, H; Matsumiya, G; Nishimura, M; Ono, M; Ryugo, M; Sawa, Y; Takano, H; Yamauchi, T | 1 |
| Fujita, K; Hosotsubo, H; Inoue, Y; Ogura, H; Shimazu, T; Sugimoto, H; Tanaka, H; Ukai, I | 1 |
| Kito, K; Minami, T | 1 |
| Dobashi, K; Hisada, T; Ishizuka, T; Mori, M; Shimizu, Y; Utsugi, M | 1 |
| Hato, F; Kato, N; Kato, T; Kitagawa, S; Kodama, T; Yukioka, H | 1 |
| Aoki, H; Endo, S; Inoue, Y; Kojika, M; Nakadate, T; Sato, N; Suzuki, Y; Yaegashi, Y; Yamada, Y; Yoshida, Y | 1 |
1 review(s) available for sivelestat and Inflammatory Response Syndrome, Systemic
| Article | Year |
|---|---|
[Pharmacological profile of a specific neutrophil elastase inhibitor, Sivelestat sodium hydrate].
Topics: Animals; Clinical Trials, Phase III as Topic; Disease Models, Animal; Glycine; Humans; Leukocyte Elastase; Serpins; Sulfonamides; Systemic Inflammatory Response Syndrome | 2003 |
7 trial(s) available for sivelestat and Inflammatory Response Syndrome, Systemic
| Article | Year |
|---|---|
Neutrophil elastase inhibitor sivelestat attenuates perioperative inflammatory response in pediatric heart surgery with cardiopulmonary bypass.
Topics: Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double-Blind Method; Female; Glycine; Humans; Infant; Inflammation; Male; Neutrophils; Prospective Studies; Proteinase Inhibitory Proteins, Secretory; Sulfonamides; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2013 |
Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, Sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV study.
Topics: Acute Lung Injury; Aged; Aged, 80 and over; Female; Glycine; Humans; Infusions, Intravenous; Male; Middle Aged; Proteinase Inhibitory Proteins, Secretory; Respiration, Artificial; Serine Proteinase Inhibitors; Sulfonamides; Survival Rate; Systemic Inflammatory Response Syndrome; Ventilator Weaning | 2011 |
Effects of sivelestat on bronchial inflammatory responses after esophagectomy.
Topics: Acute Lung Injury; Aged; Bronchitis; Esophagectomy; Female; Glycine; Humans; Interleukin-6; Interleukin-8; Leukocyte Elastase; Male; Middle Aged; Postoperative Complications; Premedication; Respiratory Distress Syndrome; Respiratory Function Tests; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2011 |
Effect of a polymorphonuclear elastase inhibitor (sivelestat sodium) on acute lung injury after cardiopulmonary bypass: findings of a double-blind randomized study.
Topics: Acute Disease; Aged; Cardiopulmonary Bypass; Female; Glycine; Humans; Interleukin-8; Leukocyte Elastase; Male; Middle Aged; Perfusion; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2006 |
A neutrophil elastase inhibitor, sivelestat, improves leukocyte deformability in patients with acute lung injury.
Topics: Adult; Aged; APACHE; C-Reactive Protein; Cell Membrane; Elasticity; Female; Glycine; Humans; Leukocyte Count; Leukocyte Elastase; Leukocytes; Lung; Lung Injury; Male; Microcirculation; Middle Aged; Norepinephrine; Oxygen; Positive-Pressure Respiration; Respiratory Distress Syndrome; Rheology; Sulfonamides; Systemic Inflammatory Response Syndrome; Total Lung Capacity | 2006 |
Neutrophil elastase as a predicting factor for development of acute lung injury.
Topics: Adult; Aged; Aged, 80 and over; Female; Glycine; Humans; Leukocyte Elastase; Male; Middle Aged; Predictive Value of Tests; Respiration, Artificial; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2007 |
Sivelestat sodium hydrate improves septic acute lung injury by reducing alveolar dysfunction.
Topics: Acute Disease; Adolescent; Adult; Aged; Glycine; Humans; Interleukin-8; Leukocyte Elastase; Leukocytes; Middle Aged; Oxygen; Pulmonary Circulation; Pulmonary Surfactant-Associated Protein D; Respiration, Artificial; Serine Proteinase Inhibitors; Sulfonamides; Survival Analysis; Systemic Inflammatory Response Syndrome; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
10 other study(ies) available for sivelestat and Inflammatory Response Syndrome, Systemic
| Article | Year |
|---|---|
Preventive effect of sivelestat on postoperative respiratory disorders after thoracic esophagectomy.
Topics: Acute Lung Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Drug Administration Schedule; Drug Therapy, Combination; Esophageal Neoplasms; Esophagectomy; Female; Glycine; Humans; Intraoperative Care; Male; Methylprednisolone; Middle Aged; Postoperative Care; Postoperative Complications; Respiratory Distress Syndrome; Respiratory Function Tests; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2013 |
Sivelestat sodium hydrate inhibits neutrophil migration to the vessel wall and suppresses hepatic ischemia-reperfusion injury.
Topics: Animals; Cell Adhesion; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycine; Immune System Diseases; Leukocyte Disorders; Liver Diseases; Male; Neutrophils; Rats; Rats, Wistar; Reperfusion Injury; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2014 |
Sivelestat sodium hydrate attenuates acute lung injury by decreasing systemic inflammation in a rat model of severe burns.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Burns; Disease Models, Animal; Glycine; Inflammation Mediators; Interleukin-8; Leukocyte Elastase; Lung; Rats; Rats, Sprague-Dawley; Sulfonamides; Systemic Inflammatory Response Syndrome | 2016 |
[Efficacy of sivelestat for acute lung injury due to severe bacterial pneumonia with systemic inflammatory response syndrome].
Topics: Acute Lung Injury; Aged; Aged, 80 and over; Female; Glycine; Humans; Leukocyte Elastase; Male; Pneumonia, Bacterial; Retrospective Studies; Serine Proteinase Inhibitors; Severity of Illness Index; Sulfonamides; Systemic Inflammatory Response Syndrome | 2008 |
A survey of the effects of sivelestat sodium administration on patients with postoperative respiratory dysfunction.
Topics: Adult; Aged; Aged, 80 and over; Female; Glycine; Health Status; Health Surveys; Humans; Inflammation; Japan; Lung Diseases; Male; Middle Aged; Postoperative Complications; Risk Factors; Serine Proteinase Inhibitors; Stress, Psychological; Sulfonamides; Systemic Inflammatory Response Syndrome | 2010 |
Hidden evidence to the West: multicentre, randomised, controlled trials in sepsis and systemic inflammatory response syndrome in Japanese journals.
Topics: Anti-Inflammatory Agents; Communication Barriers; Double-Blind Method; Evidence-Based Medicine; Glycine; Humans; Japan; Methylprednisolone; Multicenter Studies as Topic; Periodicals as Topic; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sepsis; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2004 |
Cost-minimisation analysis of sivelestat for acute lung injury associated with systemic inflammatory response syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cost Savings; Female; Glycine; Health Care Costs; Humans; Male; Markov Chains; Middle Aged; Respiratory Distress Syndrome; Sulfonamides; Systemic Inflammatory Response Syndrome | 2005 |
Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome.
Topics: Aged; Female; Glycine; Humans; Leukocyte Elastase; Male; Middle Aged; Respiratory Distress Syndrome; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2006 |
[Prophylactic effects of neutrophil elastase inhibitor for patients undergoing surgery for thoracic aortic aneurysm: a retrospective study].
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Thoracic; Cardiopulmonary Bypass; Female; Glycine; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Postoperative Complications; Proteinase Inhibitory Proteins, Secretory; Proteins; Respiratory Distress Syndrome; Retrospective Studies; Sulfonamides; Systemic Inflammatory Response Syndrome | 2006 |
Acute respiratory failure associated with miliary tuberculosis successfully treated with sivelestat sodium hydrate.
Topics: Antitubercular Agents; Glycine; Humans; Male; Middle Aged; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome; Tuberculosis, Miliary | 2006 |