sivelestat has been researched along with Disease, Pulmonary in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 10 (50.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anahtar, MN; Bhatia, SN; Chan, LW; Hern, KE; Kunz, RR; Ong, TH | 1 |
| Ando, M; Murai, T; Takahashi, Y | 1 |
| Dardik, A; Kainuma, M; Kondo, Y; Muto, A; Nishibe, T; Ohara, Y; Takeda, K | 1 |
| Asano, M; Matsumori, M; Morimoto, K; Morimoto, N; Morimoto, Y; Okada, K; Okita, Y; Takahashi, H | 1 |
| Kobayashi, N; Koizumi, T; Kubo, K; Tsushima, K; Urushihata, K; Ushiki, A; Yokoyama, T | 1 |
| Harada, N; Harimoto, N; Kakeji, Y; Koga, T; Maehara, Y; Miyazaki, M; Morita, M; Nagata, S; Oki, E; Saeki, H | 1 |
| Iwahashi, M; Naka, T; Nakamori, M; Nakamura, M; Ojima, T; Yamaue, H | 1 |
| Ishikawa, N; Kawaguchi, M; Oda, M; Tsunezuka, Y; Watanabe, G | 1 |
| Hinohara, H; Kadoi, Y; Kunimoto, F; Kuwano, H; Ogata, K; Yamaki, E | 1 |
| Fujino, Y; Fujita, Y; Maeda, Y; Mashimo, T; Nishimura, M; Uchiyama, A | 1 |
| Kobayashi, K; Kotani, Y; Nishimura, Y; Nishiuma, T; Sakashita, A; Takenaka, K; Yokoyama, M | 1 |
| Iwasaki, T; Kimura, H; Kitada, S; Maekura, R; Mori, M; Naka, N; Nakagawa, M; Nakazawa, Y; Namba, Y; Niinaka, M; Okada, T; Yano, Y; Yokota, S | 1 |
| Guo, L; Ikei, S; Ogawa, M; Sugita, H; Yamaguchi, Y | 1 |
| Hayano, T; Honda, T; Kobayashi, T; Koizumi, T; Kubo, K; Sakai, A; Sekiguchi, M | 1 |
| Homma, T; Kobayashi, T; Koyama, S; Nakagawa, S; Yoshimura, K | 1 |
| Hasegawa, N; Ishizaka, A; Kanazawa, M; Nakagawa, N; Nakamura, H; Obata, T; Sakamaki, F; Sato, K; Sayama, K; Tasaka, S; Terashima, T; Urano, T; Waki, Y | 1 |
| Kitamura, S | 1 |
| Hanaoka, M; Kaneki, T; Koizumi, T; Kubo, K; Yamamoto, H | 1 |
| Hagio, T; Kawabata, K; Matsumoto, S; Matsuoka, H; Nakao, S; Ohno, H | 1 |
| Imaki, K; Kawabata, K; Miyamoto, T; Sugitani, M; Suzuki, M; Toda, M | 1 |
1 review(s) available for sivelestat and Disease, Pulmonary
| Article | Year |
|---|---|
[Pathophysiology of acute lung injury].
Topics: Acute Disease; Animals; Biomarkers; Capillary Permeability; Cell Adhesion Molecules; Clinical Trials as Topic; Glycine; Humans; Leukocyte Elastase; Lung; Lung Diseases; Nitric Oxide; Reactive Oxygen Species; Serine Proteinase Inhibitors; Sulfonamides | 1996 |
2 trial(s) available for sivelestat and Disease, Pulmonary
| Article | Year |
|---|---|
Optimal period for the prophylactic administration of neutrophil elastase inhibitor for patients with esophageal cancer undergoing esophagectomy.
Topics: Aged; Esophageal Neoplasms; Esophagectomy; Female; Glycine; Humans; Lung Diseases; Male; Middle Aged; Postoperative Care; Postoperative Complications; Prospective Studies; Proteinase Inhibitory Proteins, Secretory; Serine Proteinase Inhibitors; Sulfonamides; Time Factors | 2011 |
[Effects of neutrophil elastase inhibitor on postoperative cytokine levels in patients after esophagectomy].
Topics: Cytokines; Esophageal Neoplasms; Esophagectomy; Glycine; Humans; Interleukin-8; Leukocyte Elastase; Lung Diseases; Postoperative Complications; Postoperative Period; Respiration, Artificial; Serpins; Sulfonamides; Time Factors | 2005 |
17 other study(ies) available for sivelestat and Disease, Pulmonary
| Article | Year |
|---|---|
Engineering synthetic breath biomarkers for respiratory disease.
Topics: alpha 1-Antitrypsin Deficiency; Animals; Biomarkers; Breath Tests; Computer Simulation; Dose-Response Relationship, Drug; Drug Carriers; Female; Glycine; Humans; Leukocyte Elastase; Lung Diseases; Mass Spectrometry; Mice, Inbred Strains; Mice, Knockout; Nanostructures; Polyethylene Glycols; Pseudomonas Infections; Sulfonamides; Volatile Organic Compounds | 2020 |
The effect of sivelestat sodium on post-cardiopulmonary bypass acute lung injury in a neonatal piglet model.
Topics: Animals; Animals, Newborn; Cardiopulmonary Bypass; Disease Models, Animal; Drug Administration Schedule; Glycine; Leukocyte Elastase; Lung; Lung Diseases; Neutrophil Activation; Neutrophils; Serine Proteinase Inhibitors; Sulfonamides; Swine; Time Factors | 2008 |
Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study.
Topics: Acute Disease; Analysis of Variance; Aortic Aneurysm, Thoracic; Aortic Dissection; Cardiopulmonary Bypass; Chi-Square Distribution; Female; Glycine; Humans; Leukocyte Count; Lung Diseases; Male; Pilot Projects; Postoperative Complications; Respiratory Function Tests; Serine Proteinase Inhibitors; Sulfonamides; Treatment Outcome | 2008 |
Sivelestat attenuates postoperative pulmonary dysfunction after total arch replacement under deep hypothermia.
Topics: Aged; Aged, 80 and over; Aorta, Thoracic; Aortic Aneurysm; Blood Vessel Prosthesis Implantation; C-Reactive Protein; Cardiopulmonary Bypass; Female; Glycine; Hemodynamics; Humans; Hypothermia, Induced; Lung Diseases; Male; Middle Aged; Oxygen; Oxygen Consumption; Partial Pressure; Postoperative Complications; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides; Treatment Outcome | 2008 |
Acute lung injury with alveolar hemorrhage due to a novel swine-origin influenza A (H1N1) virus.
Topics: Acute Lung Injury; Adult; Antiviral Agents; Female; Glycine; Hemorrhage; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lung Diseases; Oseltamivir; Sulfonamides; Treatment Outcome | 2010 |
A survey of the effects of sivelestat sodium administration on patients with postoperative respiratory dysfunction.
Topics: Adult; Aged; Aged, 80 and over; Female; Glycine; Health Status; Health Surveys; Humans; Inflammation; Japan; Lung Diseases; Male; Middle Aged; Postoperative Complications; Risk Factors; Serine Proteinase Inhibitors; Stress, Psychological; Sulfonamides; Systemic Inflammatory Response Syndrome | 2010 |
The effects of a specific neutrophil elastase inhibitor (ONO-5046) in pulmonary ischemia-reperfusion injury.
Topics: Animals; Cardiac Output; Female; Glycine; Leukocyte Elastase; Lung Diseases; Lung Transplantation; Oxygen; Pulmonary Circulation; Pulmonary Wedge Pressure; Rabbits; Reperfusion Injury; Serine Proteinase Inhibitors; Sulfonamides; Vascular Resistance | 2003 |
Effect of Ono-EI-600 elastase inhibitor on high-tidal-volume-induced lung injury in rats.
Topics: Animals; Blood Gas Analysis; Cytokines; Glycine; Lung; Lung Diseases; Male; Pancreatic Elastase; Protease Inhibitors; Rats; Rats, Wistar; Respiration, Artificial; Sulfonamides; Tidal Volume | 2006 |
Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice.
Topics: Animals; Apoptosis; Blotting, Western; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Chemokines, CXC; Enzyme-Linked Immunosorbent Assay; Glycine; Injections, Intraperitoneal; Interleukin-6; Leukocyte Elastase; Lung; Lung Diseases; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Neutrophil Infiltration; Neutrophils; Pulmonary Edema; Serine Proteinase Inhibitors; Sulfonamides; Tumor Necrosis Factor-alpha; Ventilators, Mechanical | 2007 |
[A case of lung adenocarcinoma effectively treated with sivelestat and corcicosteroid for drug-induced lung disease due to gefitinib].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Gefitinib; Glycine; Humans; Lung Diseases; Lung Neoplasms; Male; Prednisolone; Quinazolines; Serine Proteinase Inhibitors; Sulfonamides | 2008 |
Neutrophil elastase inhibitor (ONO-5046) prevents lung hemorrhage induced by lipopolysaccharide in rat model of cerulein pancreatitis.
Topics: Animals; Ceruletide; Disease Models, Animal; Drug Evaluation, Preclinical; Glycine; Hemorrhage; Leukocyte Elastase; Lipopolysaccharides; Lung Diseases; Macrophages, Peritoneal; Male; Organ Size; Pancreas; Pancreatic Elastase; Pancreatitis; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha | 1995 |
Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bacteremia; Blood Gas Analysis; Endotoxins; Escherichia coli Infections; Esterases; Glycine; Hypertension, Pulmonary; Leukocytes; Lung Diseases; Lymph; Neutrophils; Pulmonary Circulation; Sheep; Sulfonamides; Thromboxane B2 | 1994 |
Roles of neutrophil elastase and superoxide anion in leukotriene B4-induced lung injury in rabbit.
Topics: Animals; Capillary Permeability; Female; Glycine; In Vitro Techniques; Leukocyte Elastase; Leukotriene B4; Lung Diseases; Male; Neutrophils; Organ Size; Pancreatic Elastase; Pulmonary Circulation; Pulmonary Edema; Rabbits; Sulfonamides; Superoxide Dismutase; Superoxides | 1994 |
Effect of a specific neutrophil elastase inhibitor, ONO-5046, on endotoxin-induced acute lung injury.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis; Escherichia coli; Glycine; Guinea Pigs; In Vitro Techniques; Leukocyte Elastase; Lipopolysaccharides; Lung; Lung Diseases; Male; Neutrophils; Pancreatic Elastase; Serine Proteinase Inhibitors; Sulfonamides | 1996 |
Effects of lecithinized superoxide dismutase and a neutrophil elastase inhibitor (ONO-5046) on hyperoxic lung injury in rat.
Topics: Albumins; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Glycine; Hyperoxia; Leukocyte Elastase; Lung; Lung Diseases; Neutrophils; Rats; Rats, Sprague-Dawley; Sulfonamides; Superoxide Dismutase | 2000 |
Inhibition of neutrophil elastase activity attenuates complement-mediated lung injury in the hamster.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Catalase; Complement Activation; Cricetinae; Dose-Response Relationship, Drug; Elapid Venoms; Glycine; Leukocyte Elastase; Lung; Lung Diseases; Male; Mesocricetus; Neutrophils; Peroxidase; Proteins; Serine Proteinase Inhibitors; Sulfonamides; Time Factors | 2001 |
ONO-5046, a novel inhibitor of human neutrophil elastase.
Topics: Animals; Binding, Competitive; Capillary Permeability; Cricetinae; Glycine; Guinea Pigs; Hemorrhage; Humans; Lung Diseases; Male; Mesocricetus; Mice; Neutrophils; Pancreatic Elastase; Rabbits; Rats; Skin Diseases; Sulfonamides | 1991 |