sivelestat has been researched along with Acute Respiratory Distress Syndrome in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (7.41) | 18.2507 |
| 2000's | 31 (57.41) | 29.6817 |
| 2010's | 13 (24.07) | 24.3611 |
| 2020's | 6 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Jenne, DE; Korkmaz, B; Lesner, A; Marchand-Adam, S; Moss, C | 1 |
| Chen, Y; Cui, Y; Deng, Y; Fu, Q; Jiang, P; Li, J; Lin, J; Liu, Y; Meng, Q; Sun, Y; Wang, L; Wang, M; Xu, H; Ye, B; Zhang, M; Zhang, S; Zhang, T; Zhao, X | 1 |
| Gao, X; Guo, X; Huang, L; Lei, Z; Tian, J; Yang, Y; Zhang, R | 1 |
| Dong, T; Tian, W | 1 |
| Gao, Z; Li, C; Liu, L; Ma, S; Qiu, H; Xie, J; Yang, Y | 1 |
| Avan, R; Bagheri, M; Habtemariam, S; Khataminia, M; Rezai Ghaleno, H; Sadremomtaz, A; Safdari, M; Saghafi, F; Sahebnasagh, A; Talaei, Z | 1 |
| Kawakami, K; Kawasaki, Y; Kuwauchi, A; Nahara, I; Takeda, C; Takeuchi, M; Tanaka, S; Yonekura, H; Yoshida, S | 1 |
| Baba, H; Baba, Y; Hirashima, K; Iwatsuki, M; Karashima, R; Kinoshita, K; Kurashige, J; Nagai, Y; Watanabe, M | 1 |
| Hwang, JJ; Kim, DH; Kim, KD; Lee, SK; Son, BS | 1 |
| Fujishima, S; Izumida, H | 1 |
| Aibiki, M; Dote, K; Hamada, H; Higaki, J; Ito, R; Katayama, H; Miyoshi, S; Okura, T | 1 |
| Shang, Y; Sun, Z; Xia, H; Yang, Y; Yao, S | 1 |
| Imai, Y; Kawahara, M; Kuba, K; Mizushima, T; Sugizaki, T; Tamura, F; Tanaka, KI | 1 |
| Asakawa, T; Fujino, Y; Kido, T; Kubo, T; Matsuda, S; Mayumi, T; Mukae, H; Muramatsu, K; Otsubo, H; Yatera, K | 1 |
| Hiroshima, K; Iyoda, A; Moriya, Y; Shibuya, K; Yoshino, I | 1 |
| Goto, K; Hagiwara, S; Hidaka, S; Iwasaka, H; Matsumoto, S; Noguchi, T; Shingu, C | 1 |
| Gando, S; Hayakawa, M; Hoshino, H; Katabami, K; Sawamura, A; Sugano, M; Wada, T | 1 |
| Doi, A; Gremillion, DH; Igarashi, W; Iwata, K; Oba, Y; Ohji, G; Oka, H; Shimada, T; Takimoto, K | 1 |
| Inada, E; Iwanuma, Y; Kajiyama, Y; Kugimiya, T; Kumakura, S; Nagaoka, I; Sugasawa, Y; Takeuchi, K; Tsurumaru, M; Yamaguchi, K | 1 |
| Fujino, N; He, M; Kubo, H; Ota, C; Suzuki, T; Takahashi, T; Yamada, M; Yamaya, M | 1 |
| Mii, S; Nakazato, K; Sakamoto, A; Takeda, S; Tanaka, K; Tsuboko, Y; Uchida, E | 1 |
| Bellomo, R; Naka, T; Uchino, S; Wan, L | 1 |
| Artigas, A; Bernard, G; Dmitrienko, A; Jackson, K; Thompson, BT; Vincent, JL; Zeiher, BG | 1 |
| Goto, F; Hinohara, H; Ieta, K; Kadoi, Y; Kosaka, T; Kunimoto, F; Saito, S | 1 |
| Abiru, T; Aikawa, N; Hamada, C; Hirasawa, H; Ishizaka, A; Kubota, T; Matsuoka, S; Ogawa, M; Taenaka, N; Tamakuma, S | 1 |
| Sugahara, K; Takara, I; Tokumine, J; Tomiyama, H | 1 |
| Arinobu, Y; Himeji, D; Kikuchi, I; Kojima, T; Oguma, A; Ueda, A | 1 |
| Abiru, T; Aikawa, N; Fujishima, S; Kobayashi, M; Matsuoka, S | 1 |
| Akimau, P; Inoue, Y; Nishino, M; Seiyama, A; Shimazu, T; Sugimoto, H; Tanaka, H; Ukai, I | 1 |
| Andoh, K; Hoshi, K; Kaise, A; Kato, M; Kurosawa, S; Satoh, D | 1 |
| Imabayashi, T; Kakihana, Y; Kanmura, Y; Matsunaga, A; Okayama, N; Omae, T; Setoguchi, D | 1 |
| Arroliga, AC; Diaz Guzman Zavala, E; Santacruz, JF | 1 |
| Fujino, Y; Hata, H; Iwai, S; Matsuda, H; Matsumiya, G; Nishimura, M; Ono, M; Ryugo, M; Sawa, Y; Takano, H; Yamauchi, T | 1 |
| Fujita, K; Hosotsubo, H; Inoue, Y; Ogura, H; Shimazu, T; Sugimoto, H; Tanaka, H; Ukai, I | 1 |
| Hashimoto, S; Shime, N | 1 |
| Kito, K; Minami, T | 1 |
| Akaike, H; Kawasaki, K; Miyauchi, A; Ouchi, K | 1 |
| Dobashi, K; Hisada, T; Ishizuka, T; Mori, M; Shimizu, Y; Utsugi, M | 1 |
| Nakajima, H; Nakajima, S; Sawaguchi, H | 1 |
| Fukuda, I; Kondo, N; Suzuki, Y; Wakayama, F | 1 |
| Jessen, ME | 1 |
| Kaji, A; Rinka, H; Yoshida, T | 1 |
| Hato, F; Kato, N; Kato, T; Kitagawa, S; Kodama, T; Yukioka, H | 1 |
| Hida, N; Horiuchi, N; Kunikane, H; Naoki, K; Narita, Y; Okamoto, H; Watanabe, K | 1 |
| Hanada, N; Hori, K; Kusano, S; Momi, H | 1 |
| Amaya, F; Funakoshi, Y; Hashimoto, S; Ishizaka, A; Kawabata, K; Kimura, A; Okayama, Y; Shime, N | 1 |
| Harada, H; Iwasaki, H; Kunisawa, T; Kurosawa, A; Nagashima, M; Takahashi, K; Takahata, O | 1 |
| Ehara, N; Fukushima, K; Izumikawa, K; Kakeya, H; Kohno, S; Saito, A; Seki, M; Yamamoto, Y; Yanagihara, K | 1 |
| Aoshiba, K; Kakuta, Y; Konno, K; Nagai, A; Ozawa, Y; Yasui, S | 1 |
| Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M; Takao, Y | 1 |
| Inoue, T; Kyi, M; Miyake, S; Miyazaki, Y; Sawada, M; Yoshizawa, Y | 1 |
| Kitamura, S | 1 |
| Aze, Y; Hagio, T; Kawabata, K; Matsumoto, S; Nakao, S; Ohno, H; Orita, S | 1 |
| Kawabata, K; Matsuoka, S; Repine, JE; Zeiher, BG | 1 |
8 review(s) available for sivelestat and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Lung Protection by Cathepsin C Inhibition: A New Hope for COVID-19 and ARDS?
Topics: Animals; Cathepsin C; Cell Line, Tumor; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Humans; Lung; Neutrophil Infiltration; Neutrophils; Protease Inhibitors; Respiratory Distress Syndrome | 2020 |
Neutrophil elastase inhibitor (sivelestat) may be a promising therapeutic option for management of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
Topics: Acute Lung Injury; COVID-19; COVID-19 Drug Treatment; Disseminated Intravascular Coagulation; Glycine; Humans; Proteinase Inhibitory Proteins, Secretory; Respiratory Distress Syndrome; Sulfonamides; Treatment Outcome | 2020 |
[Pharmacological therapies for ARDS].
Topics: Animals; Anticoagulants; Atracurium; Disseminated Intravascular Coagulation; Glycine; Humans; Meta-Analysis as Topic; Methylprednisolone; Neuromuscular Blocking Agents; Protein C; Proteinase Inhibitory Proteins, Secretory; Pulse Therapy, Drug; Randomized Controlled Trials as Topic; Recombinant Proteins; Respiratory Distress Syndrome; Sulfonamides | 2013 |
[Effect of sivelestat sodium on the prognosis of patients with acute lung injury and acute respiratory distress syndrome: a meta-analysis].
Topics: Acute Lung Injury; China; Glycine; Humans; Intensive Care Units; Length of Stay; Prognosis; Randomized Controlled Trials as Topic; Respiration, Artificial; Respiratory Distress Syndrome; Sulfonamides | 2015 |
Effect of neutrophil elastase inhibitor (sivelestat sodium) in the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS): a systematic review and meta-analysis.
Topics: Acute Lung Injury; Glycine; Humans; Proteinase Inhibitory Proteins, Secretory; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sulfonamides | 2010 |
Update in ARDS management: recent randomized controlled trials that changed our practice.
Topics: Glycine; High-Frequency Ventilation; Humans; Liquid Ventilation; Nitric Oxide; Ohio; Positive-Pressure Respiration; Prone Position; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Survival Rate; Tidal Volume | 2006 |
[Sivelestat sodium for aspiration-related acute lung injury: a review and analysis of published case reports].
Topics: Aged; Aged, 80 and over; Female; Glycine; Humans; Male; Middle Aged; Pneumonia, Aspiration; Respiration, Artificial; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Ventilator Weaning | 2006 |
[The 74th Annual Meeting President Lecture. Pathogenesis and therapy of acute lung injury].
Topics: Glycine; Humans; Leukocyte Elastase; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides | 1999 |
8 trial(s) available for sivelestat and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Effects of intravenous sivelestat sodium on prevention of acute respiratory distress syndrome in patients with sepsis: study protocol for a double-blind multicentre randomised controlled trial.
Topics: Double-Blind Method; Humans; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sepsis; Sodium | 2023 |
Effects of sivelestat on bronchial inflammatory responses after esophagectomy.
Topics: Acute Lung Injury; Aged; Bronchitis; Esophagectomy; Female; Glycine; Humans; Interleukin-6; Interleukin-8; Leukocyte Elastase; Male; Middle Aged; Postoperative Complications; Premedication; Respiratory Distress Syndrome; Respiratory Function Tests; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2011 |
Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study.
Topics: Australia; Belgium; Canada; Double-Blind Method; Female; Follow-Up Studies; Glycine; Guideline Adherence; Humans; Infusions, Intravenous; Leukocyte Elastase; Male; Middle Aged; New Zealand; Outcome and Process Assessment, Health Care; Prospective Studies; Respiration, Artificial; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Spain; Sulfonamides; Survival Analysis; Tidal Volume; Time; Treatment Outcome; United States | 2004 |
Pilot study of the effects of ONO-5046 in patients with acute respiratory distress syndrome.
Topics: Adult; Aged; Cytokines; Double-Blind Method; Female; Glycine; Humans; Leukocyte Elastase; Male; Middle Aged; Pilot Projects; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides | 2004 |
Relationship between neutrophil elastase and acute lung injury in humans.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glycine; Humans; Intensive Care Units; Length of Stay; Leukocyte Elastase; Male; Middle Aged; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Function Tests; Serine Proteinase Inhibitors; Sulfonamides; Ventilator Weaning | 2004 |
Effect of a polymorphonuclear elastase inhibitor (sivelestat sodium) on acute lung injury after cardiopulmonary bypass: findings of a double-blind randomized study.
Topics: Acute Disease; Aged; Cardiopulmonary Bypass; Female; Glycine; Humans; Interleukin-8; Leukocyte Elastase; Male; Middle Aged; Perfusion; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2006 |
A neutrophil elastase inhibitor, sivelestat, improves leukocyte deformability in patients with acute lung injury.
Topics: Adult; Aged; APACHE; C-Reactive Protein; Cell Membrane; Elasticity; Female; Glycine; Humans; Leukocyte Count; Leukocyte Elastase; Leukocytes; Lung; Lung Injury; Male; Microcirculation; Middle Aged; Norepinephrine; Oxygen; Positive-Pressure Respiration; Respiratory Distress Syndrome; Rheology; Sulfonamides; Systemic Inflammatory Response Syndrome; Total Lung Capacity | 2006 |
Neutrophil elastase as a predicting factor for development of acute lung injury.
Topics: Adult; Aged; Aged, 80 and over; Female; Glycine; Humans; Leukocyte Elastase; Male; Middle Aged; Predictive Value of Tests; Respiration, Artificial; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2007 |
38 other study(ies) available for sivelestat and Acute Respiratory Distress Syndrome
| Article | Year |
|---|---|
Elastase Inhibitor Cyclotheonellazole A: Total Synthesis and In Vivo Biological Evaluation for Acute Lung Injury.
Topics: Acute Lung Injury; Animals; Bleomycin; Cell Line; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Humans; Leukocyte Elastase; Male; Mice; Mice, Inbred C57BL; Peptides, Cyclic; Respiratory Distress Syndrome; Serine Proteinase Inhibitors | 2022 |
Efficacy, safety, and pharmacoeconomics of sivelestat sodium in the treatment of septic acute respiratory distress syndrome: a retrospective cohort study.
Topics: Economics, Pharmaceutical; Glycine; Humans; Respiratory Distress Syndrome; Retrospective Studies; Sodium; Sulfonamides | 2021 |
[Comparative study of the protective effect of Xuebijing injection and Sivelestat sodium on acute lung injury/acute respiratory distress syndrome rats].
Topics: Acute Lung Injury; Animals; Drugs, Chinese Herbal; Glycine; Interleukin-6; Lipopolysaccharides; Lung; Male; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Sulfonamides | 2022 |
Prophylactic sivelestat for esophagectomy and in-hospital mortality: a propensity score-matched analysis of claims database.
Topics: Aged; Databases, Factual; Esophagectomy; Female; Glycine; Hospitals; Humans; Japan; Male; Middle Aged; Postoperative Complications; Propensity Score; Respiratory Distress Syndrome; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides | 2019 |
Preventive effect of sivelestat on postoperative respiratory disorders after thoracic esophagectomy.
Topics: Acute Lung Injury; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Drug Administration Schedule; Drug Therapy, Combination; Esophageal Neoplasms; Esophagectomy; Female; Glycine; Humans; Intraoperative Care; Male; Methylprednisolone; Middle Aged; Postoperative Care; Postoperative Complications; Respiratory Distress Syndrome; Respiratory Function Tests; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2013 |
The use of neutrophil elastase inhibitor in the treatment of acute lung injury after pneumonectomy.
Topics: Acute Lung Injury; Adult; Aged; Combined Modality Therapy; Drug Administration Schedule; Glycine; Humans; Infusions, Intravenous; Male; Middle Aged; Pneumonectomy; Postoperative Complications; Proteinase Inhibitory Proteins, Secretory; Respiration, Artificial; Respiratory Distress Syndrome; Retrospective Studies; Sulfonamides; Treatment Outcome | 2013 |
Combination therapy with sivelestat and recombinant human soluble thrombomodulin for ARDS and DIC patients.
Topics: Aged; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female; Glycine; Humans; Male; Middle Aged; Recombinant Proteins; Respiratory Distress Syndrome; Retrospective Studies; Solubility; Sulfonamides; Thrombomodulin | 2014 |
Evaluation of Lecithinized Superoxide Dismutase for the Prevention of Acute Respiratory Distress Syndrome in Animal Models.
Topics: Animals; Cecum; Dexamethasone; Disease Models, Animal; Glycine; Ligation; Lipopolysaccharides; Lung Injury; Male; Mice; Mice, Inbred ICR; Multiple Organ Failure; Phosphatidylcholines; Punctures; Reactive Oxygen Species; Respiration, Artificial; Respiratory Distress Syndrome; Sulfonamides; Superoxide Dismutase | 2017 |
Efficacy of early sivelestat administration on acute lung injury and acute respiratory distress syndrome.
Topics: Acute Lung Injury; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Glycine; Humans; Male; Prognosis; Respiratory Distress Syndrome; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides; Time Factors; Treatment Outcome | 2017 |
Successful management of postoperative acute respiratory distress syndrome in a patient with lung cancer.
Topics: Adrenal Cortex Hormones; Aged; Drug Therapy, Combination; Glycine; Humans; Lung Neoplasms; Male; Pneumonectomy; Proteinase Inhibitory Proteins, Secretory; Radiography, Thoracic; Respiratory Distress Syndrome; Sulfonamides; Tomography, X-Ray Computed; Treatment Outcome | 2008 |
Sivelestat treatment for acute respiratory distress syndrome in an infant.
Topics: Anti-Inflammatory Agents; C-Reactive Protein; Cardiopulmonary Resuscitation; Glycine; Humans; Hypoxia, Brain; Immunosuppressive Agents; Infant; Leukocyte Count; Leukocyte Elastase; Male; Oxygen; Positive-Pressure Respiration; Protein Kinase Inhibitors; Radiography; Respiratory Distress Syndrome; Sulfonamides | 2009 |
Sivelestat (selective neutrophil elastase inhibitor) improves the mortality rate of sepsis associated with both acute respiratory distress syndrome and disseminated intravascular coagulation patients.
Topics: Adult; Aged; Disseminated Intravascular Coagulation; Female; Glycine; Humans; Male; Middle Aged; Respiratory Distress Syndrome; Retrospective Studies; Sepsis; Serine Proteinase Inhibitors; Sulfonamides; Treatment Outcome | 2010 |
Administration of a specific inhibitor of neutrophil elastase attenuates pulmonary fibrosis after acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cell Movement; Collagen; Glycine; Leukocyte Elastase; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Smad2 Protein; Smad3 Protein; Sulfonamides; Transforming Growth Factor beta1 | 2012 |
Clinical evaluation of sivelestat for acute lung injury/acute respiratory distress syndrome following surgery for abdominal sepsis.
Topics: Abdomen; Acute Lung Injury; Aged; Female; Glycine; Humans; Male; Middle Aged; Postoperative Complications; Proteinase Inhibitory Proteins, Secretory; Respiratory Distress Syndrome; Sepsis; Sulfonamides; Ventilator Weaning | 2012 |
Hidden evidence to the West: multicentre, randomised, controlled trials in sepsis and systemic inflammatory response syndrome in Japanese journals.
Topics: Anti-Inflammatory Agents; Communication Barriers; Double-Blind Method; Evidence-Based Medicine; Glycine; Humans; Japan; Methylprednisolone; Multicenter Studies as Topic; Periodicals as Topic; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sepsis; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2004 |
[Sivelestat sodium hydrate was effective for ARDS in a patient suffering from chronic rheumatoid arthritis with acute exacerbation after failing to respond to high dose steroid pulse therapy].
Topics: Antigens; Antigens, Neoplasm; Arthritis, Rheumatoid; Biomarkers; Female; Glycine; Glycoproteins; Humans; Leukocyte Elastase; Methylprednisolone; Middle Aged; Mucin-1; Mucins; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Pulse Therapy, Drug; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Treatment Outcome | 2004 |
[A case of Legionella pneumonia complicated with acute respiratory distress syndrome treated with methylprednisolone and sivelestat sodium in combination with intravenous erythromycin and ciprofloxacin].
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Erythromycin; Glycine; Humans; Infusions, Intravenous; Legionnaires' Disease; Male; Methylprednisolone; Middle Aged; Respiratory Distress Syndrome; Sulfonamides | 2004 |
Cost-minimisation analysis of sivelestat for acute lung injury associated with systemic inflammatory response syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cost Savings; Female; Glycine; Health Care Costs; Humans; Male; Markov Chains; Middle Aged; Respiratory Distress Syndrome; Sulfonamides; Systemic Inflammatory Response Syndrome | 2005 |
Protective effects of a selective neutrophil elastase inhibitor (sivelestat) on lipopolysaccharide-induced acute dysfunction of the pulmonary microcirculation.
Topics: Analysis of Variance; Animals; Cell Adhesion; Glycine; Hemodynamics; Leukocyte Elastase; Leukocytes; Lipopolysaccharides; Male; Microcirculation; Microscopy, Polarization; Microscopy, Video; Microspectrophotometry; Pulmonary Circulation; Random Allocation; Rats; Rats, Wistar; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides | 2005 |
Sivelestat, a neutrophil elastase inhibitor, reduces mortality rate of critically ill patients.
Topics: Aged; Aged, 80 and over; Critical Illness; Female; Glycine; Hospitals, University; Hospitals, Urban; Humans; Intensive Care Units; Japan; Length of Stay; Leukocyte Elastase; Male; Middle Aged; Multiple Organ Failure; Respiratory Distress Syndrome; Retrospective Studies; Sulfonamides; Treatment Outcome | 2005 |
Clinical effects of a neutrophil elastase inhibitor, sivelestat, in patients with acute respiratory distress syndrome.
Topics: Aged; Female; Glycine; Humans; Leukocyte Elastase; Male; Middle Aged; Respiratory Distress Syndrome; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2006 |
[Prophylactic effects of neutrophil elastase inhibitor for patients undergoing surgery for thoracic aortic aneurysm: a retrospective study].
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Thoracic; Cardiopulmonary Bypass; Female; Glycine; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Postoperative Complications; Proteinase Inhibitory Proteins, Secretory; Proteins; Respiratory Distress Syndrome; Retrospective Studies; Sulfonamides; Systemic Inflammatory Response Syndrome | 2006 |
Sivelestat relieves respiratory distress refractory to dexamethasone in all-trans retinoic acid syndrome: a report of two cases.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytoprotection; Dexamethasone; Female; Glycine; Humans; Intracranial Hemorrhages; Leukemia, Promyelocytic, Acute; Male; Prospective Studies; Radiography; Randomized Controlled Trials as Topic; Remission Induction; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Tretinoin | 2006 |
Acute respiratory failure associated with miliary tuberculosis successfully treated with sivelestat sodium hydrate.
Topics: Antitubercular Agents; Glycine; Humans; Male; Middle Aged; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome; Tuberculosis, Miliary | 2006 |
[Survival by a young woman with malnutrition due to alcoholism and eating disorders and with acute respiratory distress syndrome due to severe pneumonia who showed increased serum neutrophil elastase activity].
Topics: Adult; Alcoholism; Feeding and Eating Disorders; Female; Glycine; Humans; Leukocyte Elastase; Malnutrition; Pneumonia, Pneumococcal; Respiratory Distress Syndrome; Sulfonamides | 2006 |
Neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury after cardiopulmonary bypass in the rabbit endotoxemia model.
Topics: Animals; Cardiopulmonary Bypass; Glycine; Interleukin-8; Leukocyte Elastase; Lipopolysaccharides; Neutrophils; Peroxidase; Rabbits; Respiratory Distress Syndrome; Sulfonamides | 2007 |
Invited commentary.
Topics: Animals; Cardiopulmonary Bypass; Glycine; Leukocyte Elastase; Lipopolysaccharides; Rabbits; Respiratory Distress Syndrome; Sulfonamides | 2007 |
[A case of idiopathic ARDS treated by sivelestat sodium and fluid management based on extravascular lung water index].
Topics: Aged; Extravascular Lung Water; Female; Fluid Therapy; Glycine; Humans; Leukocyte Elastase; Respiration, Artificial; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides | 2006 |
[A case of legionella pneumonia associated with acute respiratory distress syndrome (ARDS) and acute renal failure treated with methylprednisolone and sivelestat].
Topics: Acute Kidney Injury; Glucocorticoids; Glycine; Humans; Legionnaires' Disease; Male; Methylprednisolone; Middle Aged; Respiratory Distress Syndrome; Sulfonamides | 2007 |
[Good response in ARDS treated with sivelestat sodium hydrate during chemotherapy for cholangiocarcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Drug Administration Schedule; Drug Combinations; Glycine; Humans; Male; Neutropenia; Oxonic Acid; Paclitaxel; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Tegafur | 2007 |
Neutrophil elastase activity in acute lung injury and respiratory distress syndrome.
Topics: Aged; alpha 1-Antitrypsin; Enzyme Inhibitors; Female; Glycine; Humans; Leukocyte Elastase; Male; Middle Aged; Respiratory Distress Syndrome; Sulfonamides | 2008 |
[Case of severe transfusion-related acute lung injury during coronary artery bypass surgery].
Topics: Aged; Angina Pectoris; Antibodies; Coronary Artery Bypass; Glycine; Granulocytes; HLA Antigens; Humans; Intraoperative Complications; Male; Respiratory Distress Syndrome; Severity of Illness Index; Sulfonamides; Transfusion Reaction | 2008 |
Severe Legionnaires' disease successfully treated using a combination of fluoroquinolone, erythromycin, corticosteroid, and sivelestat.
Topics: Adrenal Cortex Hormones; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Erythromycin; Fluoroquinolones; Glycine; Humans; Legionnaires' Disease; Male; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Treatment Outcome | 2008 |
A specific neutrophil elastase inhibitor (ONO-5046.Na) attenuates LPS-induced acute lung inflammation in the hamster.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis, Leukocyte; Cricetinae; Glycine; Leukocyte Elastase; Lipopolysaccharides; Lung; Male; Mesocricetus; Neutrophils; Organ Size; Pancreatic Elastase; Pneumonia; Respiratory Distress Syndrome; Sulfonamides | 1995 |
ONO-5046, an elastase inhibitor, attenuates endotoxin-induced acute lung injury in rabbits.
Topics: Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Endotoxins; Escherichia coli; Glycine; Hemodynamics; Leukocyte Count; Lung; Lung Compliance; Male; Organ Size; Pancreatic Elastase; Platelet Count; Rabbits; Respiratory Distress Syndrome; Sulfonamides | 1997 |
Effects of a neutrophil elastase inhibitor (ONO-5046) on acute pulmonary injury induced by tumor necrosis factor alpha (TNFalpha) and activated neutrophils in isolated perfused rabbit lungs.
Topics: Animals; Capillary Permeability; Carcinogens; Disease Models, Animal; Drug Evaluation, Preclinical; Glycine; Infusions, Intravenous; Leukocyte Elastase; Neutrophil Activation; Pulmonary Wedge Pressure; Rabbits; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Delayed neutrophil elastase inhibition prevents subsequent progression of acute lung injury induced by endotoxin inhalation in hamsters.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Disease Progression; Endotoxins; Glycine; Leukocyte Count; Leukocyte Elastase; Lung; Male; Mesocricetus; Neutrophils; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides | 2000 |
Neutrophil elastase and acute lung injury: prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics.
Topics: Animals; Endothelium, Vascular; Glycine; Humans; Leukocyte Elastase; Oxidative Stress; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Xanthine Oxidase | 2002 |