sivelestat has been researched along with Acute Liver Injury, Drug-Induced in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Albeck, A; Khalfin, B; Lichtenstein, A; Nathan, I | 1 |
| Harie, I; Ishida, Y; Ishigami, A; Kimura, A; Kondo, T; Kuninaka, Y; Mukaida, N; Nosaka, M; Zhang, S | 1 |
| Colle, I; Debacker, PJ; Devisscher, L; Geerts, A; Lefere, S; Raevens, S; Van Campenhout, S; Van Vlierberghe, H; Verhelst, X | 1 |
| Kwon, AH; Qiu, Z | 1 |
| Ishihara, H; Kudoh, A; Kudoh, E; Matsuki, A | 1 |
6 other study(ies) available for sivelestat and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Targeting Necrosis: Elastase-like Protease Inhibitors Curtail Necrotic Cell Death Both
Topics: Animals; Brain Injuries, Traumatic; Cell Death; Chemical and Drug Induced Liver Injury; High-Throughput Screening Assays; Humans; Mice, Inbred BALB C; Mice, Inbred C57BL; Myocardial Infarction; Necroptosis; Necrosis; Pancreatic Elastase; Protease Inhibitors; RNA, Small Interfering; U937 Cells | 2021 |
Essential Involvement of Neutrophil Elastase in Acute Acetaminophen Hepatotoxicity Using BALB/c Mice.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Leukocyte Elastase; Liver Diseases; Mice; Mice, Inbred BALB C; Necrosis; Transaminases | 2023 |
Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Free Radical Scavengers; Glycine; Inflammation; Male; Mice; Mice, Inbred C57BL; Serine Proteinase Inhibitors; Sulfonamides | 2020 |
Neutrophil elastase inhibitor prevents endotoxin-induced liver injury following experimental partial hepatectomy.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endotoxins; Glycine; Hepatectomy; Humans; Leukocyte Elastase; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Sulfonamides | 2007 |
ONO-5046, an elastase inhibitor, attenuates liver mitochondrial dysfunction after endotoxin.
Topics: Adenosine Diphosphate; Animals; Blood Pressure; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Escherichia coli; Glycine; Guinea Pigs; Ketone Bodies; Leukocyte Elastase; Lipopolysaccharides; Liver Diseases; Male; Mitochondria, Liver; Oxygen; Phosphorylation; Respiration; Serine Proteinase Inhibitors; Sulfonamides | 1998 |