sivelestat has been researched along with Acute Disease in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 11 (64.71) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Gong, H; Ma, P; Tang, A; Wang, H; Wang, S | 1 |
| Arimura-Omori, M; Hamada, N; Harada, E; Ikeda-Harada, C; Mikumo, H; Nakanishi, Y; Ogata-Suetsugu, S; Suzuki, K; Yanagihara, T; Yokoyama, T | 1 |
| Kunihara, T; Matsui, Y; Matsuzaki, K; Murashita, T; Shiiya, N; Shingu, Y | 1 |
| Chida, K; Fujisawa, T; Harada, M; Imokawa, S; Mori, K; Sagisaka, S; Sano, T; Suda, T; Uchiyama, H; Ukita, T; Yasuda, K | 1 |
| Dardik, A; Kainuma, M; Kondo, Y; Muto, A; Nishibe, T; Ohara, Y; Takeda, K | 1 |
| Fujita, K; Hata, M; Minami, K; Niino, T; Osaka, S; Sezai, A; Shimura, K; Unosawa, S; Yoshitake, I | 1 |
| Hayashi, S; Ikegame, Y; Iwama, T; Nakashima, S; Yamashita, K; Yoshimura, S | 1 |
| Hagio, T; Kawabata, K; Matsumoto, S; Matsuoka, S; Nakao, S | 1 |
| Chida, K; Enomoto, N; Imokawa, S; Nagayama, M; Sano, T; Suda, T; Todate, A; Uchiyama, H; Yasuda, K | 1 |
| Fujino, Y; Hata, H; Iwai, S; Matsuda, H; Matsumiya, G; Nishimura, M; Ono, M; Ryugo, M; Sawa, Y; Takano, H; Yamauchi, T | 1 |
| Fukunaga, M; Iba, T; Kidokoro, A; Sugimotoa, K; Takuhiro, K; Yoshikawa, S | 1 |
| Amano, J; Fukui, D; Furusawa, T; Sakaguchi, M; Seto, T; Terasaki, T; Tsukioka, K; Wada, Y | 1 |
| Funakoshi, Y; Ishizaka, A; Katori, N; Kawabata, K; Kotake, Y; Morisaki, H; Nakamura, N; Suzuki, T; Takeda, J; Yajima, S; Yamada, S | 1 |
| Kozawa, S; Miyazawa, N; Nakamura, M; Ogura, T; Tagawa, A; Takahashi, H; Watanuki, Y | 1 |
| Aoki, H; Endo, S; Inoue, Y; Kojika, M; Nakadate, T; Sato, N; Suzuki, Y; Yaegashi, Y; Yamada, Y; Yoshida, Y | 1 |
| Hasegawa, N; Ishizaka, A; Kanazawa, M; Nakagawa, N; Nakamura, H; Obata, T; Sakamaki, F; Sato, K; Sayama, K; Tasaka, S; Terashima, T; Urano, T; Waki, Y | 1 |
| Kitamura, S | 1 |
1 review(s) available for sivelestat and Acute Disease
| Article | Year |
|---|---|
[Pathophysiology of acute lung injury].
Topics: Acute Disease; Animals; Biomarkers; Capillary Permeability; Cell Adhesion Molecules; Clinical Trials as Topic; Glycine; Humans; Leukocyte Elastase; Lung; Lung Diseases; Nitric Oxide; Reactive Oxygen Species; Serine Proteinase Inhibitors; Sulfonamides | 1996 |
3 trial(s) available for sivelestat and Acute Disease
| Article | Year |
|---|---|
[Effect of sivelestat sodium on acute lung injury after acute aortic dissection].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aortic Aneurysm; Aortic Dissection; Female; Glycine; Humans; Infusions, Intravenous; Leukocyte Elastase; Logistic Models; Male; Middle Aged; Proteinase Inhibitory Proteins, Secretory; Respiratory Insufficiency; Sulfonamides | 2008 |
Effect of a polymorphonuclear elastase inhibitor (sivelestat sodium) on acute lung injury after cardiopulmonary bypass: findings of a double-blind randomized study.
Topics: Acute Disease; Aged; Cardiopulmonary Bypass; Female; Glycine; Humans; Interleukin-8; Leukocyte Elastase; Male; Middle Aged; Perfusion; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Systemic Inflammatory Response Syndrome | 2006 |
Sivelestat sodium hydrate improves septic acute lung injury by reducing alveolar dysfunction.
Topics: Acute Disease; Adolescent; Adult; Aged; Glycine; Humans; Interleukin-8; Leukocyte Elastase; Leukocytes; Middle Aged; Oxygen; Pulmonary Circulation; Pulmonary Surfactant-Associated Protein D; Respiration, Artificial; Serine Proteinase Inhibitors; Sulfonamides; Survival Analysis; Systemic Inflammatory Response Syndrome; Treatment Outcome; Tumor Necrosis Factor-alpha | 2006 |
13 other study(ies) available for sivelestat and Acute Disease
| Article | Year |
|---|---|
Combined effects of sivelestat and resveratrol on severe acute pancreatitis-associated lung injury in rats.
Topics: Acute Disease; Amylases; Animals; Arterial Pressure; Bronchoalveolar Lavage Fluid; Glycine; Interleukin-6; Leukocyte Elastase; Lung; Lung Injury; Male; Oxygen; Pancreatitis; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Sulfonamides | 2014 |
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib-naphthalene-induced acute pneumonitis in mice.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Female; Gefitinib; Glycine; Humans; Kaplan-Meier Estimate; Leukocyte Count; Leukocyte Elastase; Lung; Mice, Inbred C57BL; Naphthalenes; Neutrophils; Pneumonia; Quinazolines; Serine Proteinase Inhibitors; Sulfonamides; Weight Loss | 2017 |
[Acute respiratory failure due to pneumocystis pneumonia successfully treated with combined use of sivelestat sodium hydrate].
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Drug Therapy, Combination; Ganciclovir; Glycine; Humans; Male; Methylprednisolone; Pneumonia, Pneumocystis; Proteinase Inhibitory Proteins, Secretory; Pulse Therapy, Drug; Respiratory Insufficiency; Severity of Illness Index; Sulfonamides; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2008 |
Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study.
Topics: Acute Disease; Analysis of Variance; Aortic Aneurysm, Thoracic; Aortic Dissection; Cardiopulmonary Bypass; Chi-Square Distribution; Female; Glycine; Humans; Leukocyte Count; Lung Diseases; Male; Pilot Projects; Postoperative Complications; Respiratory Function Tests; Serine Proteinase Inhibitors; Sulfonamides; Treatment Outcome | 2008 |
Efficacy of neutrophil elastase inhibitor on type A acute aortic dissection.
Topics: Acute Disease; Aged; Antithrombin III; Aortic Aneurysm; Aortic Dissection; Blood Vessel Prosthesis Implantation; C-Reactive Protein; Female; Glycine; Humans; Infusions, Intravenous; International Normalized Ratio; Leukocyte Count; Leukocyte Elastase; Lung; Male; Middle Aged; Partial Thromboplastin Time; Platelet Count; Postoperative Hemorrhage; Prothrombin Time; Respiratory Function Tests; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides; Time Factors; Treatment Outcome | 2010 |
Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema.
Topics: Acute Disease; Angiopoietin-1; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Cells, Cultured; Glycine; Humans; Hypoxia-Ischemia, Brain; Leukocyte Elastase; Male; Mice; Mice, Inbred C57BL; Microvessels; Proteinase Inhibitory Proteins, Secretory; Sulfonamides | 2010 |
Sivelestat, a specific neutrophil elastase inhibitor, prevented phorbol myristate acetate-induced acute lung injury in conscious rabbits.
Topics: Acute Disease; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Glycine; Hemorrhage; Injections, Intravenous; Leukocyte Elastase; Lung; Male; Organ Size; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Proteins; Pulmonary Alveoli; Pulmonary Edema; Rabbits; Respiratory Insufficiency; Sulfonamides; Tetradecanoylphorbol Acetate | 2005 |
[Two cases of acute respiratory failure due to idiopathic interstitial pneumonia successfully treated with sivelestat sodium hydrate and steroid therapy].
Topics: Acute Disease; Aged; Drug Therapy, Combination; Female; Glycine; Humans; Lung Diseases, Interstitial; Male; Methylprednisolone; Middle Aged; Prednisolone; Respiratory Insufficiency; Serine Proteinase Inhibitors; Sulfonamides | 2006 |
Pretreatment of sivelestat sodium hydrate improves the lung microcirculation and alveolar damage in lipopolysaccharide-induced acute lung inflammation in hamsters.
Topics: Acute Disease; Animals; Cricetinae; Glycine; Leukocyte Elastase; Lipopolysaccharides; Male; Microcirculation; Pneumonia; Pulmonary Alveoli; Pulmonary Circulation; Serine Proteinase Inhibitors; Sulfonamides | 2006 |
The effects of a neutrophil elastase inhibitor on the postoperative respiratory failure of acute aortic dissection.
Topics: Acute Disease; Aged; Aortic Aneurysm; Aortic Dissection; Cardiopulmonary Bypass; Female; Glycine; Humans; Male; Postoperative Care; Proteinase Inhibitory Proteins, Secretory; Respiratory Insufficiency; Retrospective Studies; Serine Proteinase Inhibitors; Sulfonamides | 2006 |
Inhibition of neutrophil elastase attenuates gut mucosal injury evoked by acute alveolar hypoxia in rabbits.
Topics: Acute Disease; Animals; Glycine; HMGB1 Protein; Hypoxia; Intestinal Mucosa; Leukocyte Elastase; Male; Neutrophils; Permeability; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Rabbits; Sulfonamides | 2007 |
[Outcome of patients with acute exacerbation of idiopathic interstitial fibrosis (IPF) treated with sivelestat and the prognostic value of serum KL-6 and surfactant protein D].
Topics: Acute Disease; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers; Chronic Disease; Disease Progression; Female; Glycine; Humans; Leukocyte Elastase; Male; Middle Aged; Mucin-1; Mucins; Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein D; Respiratory Insufficiency; Serine Proteinase Inhibitors; Sulfonamides; Treatment Outcome | 2007 |
Effect of a specific neutrophil elastase inhibitor, ONO-5046, on endotoxin-induced acute lung injury.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis; Escherichia coli; Glycine; Guinea Pigs; In Vitro Techniques; Leukocyte Elastase; Lipopolysaccharides; Lung; Lung Diseases; Male; Neutrophils; Pancreatic Elastase; Serine Proteinase Inhibitors; Sulfonamides | 1996 |