sitagliptin-phosphate and Dementia--Vascular

Vascular dementia (VaD) is the second most prevalent type of dementia characterized by progressive cognitive deficits and is a major risk factor for the development of Alzheimer's disease and other neurodegenerative disorders. This study is aimed at determining the potential neuroprotective effect of sitagliptin (STG) on cognitive deficits in L-methionine-induced VaD in rats and the possible underlying mechanisms. 30 adult male Wistar albino rats were divided equally (

Topics: Animals; Brain-Derived Neurotrophic Factor; Cognition; Dementia, Vascular; Disease Models, Animal; Hippocampus; Male; Maze Learning; Methionine; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Sitagliptin Phosphate