Compounds > sirolimus

sirolimus and Scleroderma--Diffuse

sirolimus has been researched along with Scleroderma--Diffuse* in 2 studies

Trials

1 trial(s) available for sirolimus and Scleroderma--Diffuse

ArticleYear
Rapamycin versus methotrexate in early diffuse systemic sclerosis: results from a randomized, single-blind pilot study.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:12

    To assess the safety and efficacy of rapamycin in the treatment of diffuse systemic sclerosis (SSc; scleroderma).. Eighteen patients with diffuse SSc of

    Topics: Adolescent; Adult; Aged; Female; Health Status; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pilot Projects; Scleroderma, Diffuse; Sirolimus; Skin; Surveys and Questionnaires; Treatment Outcome; Young Adult

2009

Other Studies

1 other study(ies) available for sirolimus and Scleroderma--Diffuse

ArticleYear
Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis: Implications for Scleroderma.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:11

    Topics: Biomarkers; Biopsy, Needle; Cells, Cultured; Fibroblasts; Fibrosis; Humans; Imidazoles; Immunohistochemistry; Molecular Targeted Therapy; Phosphorylation; Polymerase Chain Reaction; Scleroderma, Diffuse; Sensitivity and Specificity; Sirolimus; Smad2 Protein; TOR Serine-Threonine Kinases; Transforming Growth Factor beta; Triazines

2015