sirolimus has been researched along with Leukemia--Erythroblastic--Acute* in 2 studies
2 other study(ies) available for sirolimus and Leukemia--Erythroblastic--Acute
| Article | Year |
|---|---|
Expression of (Pro)renin Receptor During Rapamycin-Induced Erythropoiesis in K562 Erythroleukemia Cells and Its Possible Dual Actions on Erythropoiesis.
(Pro)renin receptor ((P)RR), a specific receptor for renin and prorenin, is expressed in erythroblastic cells. (P)RR has multiple biological actions: prorenin activation, stimulation of the intracellular signaling including extracellular signal-regulated kinases, and functional complex formation with vacuolar H Topics: 5-Aminolevulinate Synthetase; Erythropoiesis; Hemoglobins; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Macrolides; Models, Biological; Prorenin Receptor; Receptors, Cell Surface; RNA, Messenger; RNA, Small Interfering; Sirolimus; TOR Serine-Threonine Kinases | 2017 |
Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells.
A series of carbamides derived from 1,2:5,6-di-O-isopropylidene-D-gluco- and D-allofuranose as well as their 5,6-O-deprotected analogues (2 and 4) and methyl 3,4-O-isopropylidene-alpha- and beta-D-galactopyranosides (5 and 6) have been prepared in order to evaluate their ability to induce erythroid differentiation of human erythroleukemic K562 cells. Twenty out of 51 carbamides tested exhibit an appreciable activity as inducers of erythroid differentiation and have been fully characterized and described. Topics: Antineoplastic Agents; Cell Differentiation; Drug Screening Assays, Antitumor; Erythroid Cells; Galactose; Glucose; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Monosaccharides; Pentoses; Structure-Activity Relationship; Urea | 2009 |