sirolimus and Eyelid-Diseases

sirolimus has been researched along with Eyelid-Diseases* in 2 studies

Trials

1 trial(s) available for sirolimus and Eyelid-Diseases

Article	Year
Sirolimus-associated eyelid edema in kidney transplant recipients. Transplantation, 2001, Jul-15, Volume: 72, Issue:1 The immunosuppressant sirolimus is effective in preventing acute rejection episodes. So far, unusual edema formation has not been reported as a side effect.. Two groups of patients with renal transplants, consisting of 11 patients each, were followed for up to 29 months. The immunosuppressive regimen was either sirolimus and prednisone with or without cyclosporine or azathioprine/mycophenolate and prednisone with cyclosporine. Routine follow-up included a thorough clinical investigation. Edema formation was documented photographically.. In 5 of the 11 patients treated with sirolimus uni- or bilateral, non-itching, eyelid edema was observed. After discontinuation of sirolimus, lid edema disappeared. The duration until recovery varied from weeks to months. No cause of edema formation other than the treatment with sirolimus was detected.. Severe eyelid edema formation seems to be associated with sirolimus treatment. The underlying mechanism is unknown. Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Edema; Eyelid Diseases; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Retrospective Studies; Sirolimus	2001

Article

Year

Sirolimus-associated eyelid edema in kidney transplant recipients.

Transplantation, 2001, Jul-15, Volume: 72, Issue:1

The immunosuppressant sirolimus is effective in preventing acute rejection episodes. So far, unusual edema formation has not been reported as a side effect.. Two groups of patients with renal transplants, consisting of 11 patients each, were followed for up to 29 months. The immunosuppressive regimen was either sirolimus and prednisone with or without cyclosporine or azathioprine/mycophenolate and prednisone with cyclosporine. Routine follow-up included a thorough clinical investigation. Edema formation was documented photographically.. In 5 of the 11 patients treated with sirolimus uni- or bilateral, non-itching, eyelid edema was observed. After discontinuation of sirolimus, lid edema disappeared. The duration until recovery varied from weeks to months. No cause of edema formation other than the treatment with sirolimus was detected.. Severe eyelid edema formation seems to be associated with sirolimus treatment. The underlying mechanism is unknown.

Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Edema; Eyelid Diseases; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Retrospective Studies; Sirolimus

2001

Other Studies

1 other study(ies) available for sirolimus and Eyelid-Diseases

Article	Year
[Edema of the eyelids caused by sirolimus in renal transplant recipients]. Annales de dermatologie et de venereologie, 2003, Volume: 130, Issue:1 Pt 1 Topics: Edema; Eyelid Diseases; Humans; Immunosuppressive Agents; Kidney Transplantation; Sirolimus	2003