sinefungin has been researched along with 2019 Novel Coronavirus Disease in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 6 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed-Belkacem, R; Canard, B; Debart, F; Decroly, E; Guiraud, M; Sutto-Ortiz, P; Vasseur, JJ | 1 |
| Ahmed-Belkacem, R; Canard, B; Colmant, AMG; Coutard, B; Debart, F; Decroly, E; Delpal, A; Hausdorff, M; Ogando, NS; Snijder, EJ; Sutto-Ortiz, P; Touret, F; Vasseur, JJ | 1 |
| Boura, E; Krafcikova, P; Nencka, R; Silhan, J | 1 |
| Brunzelle, J; Inniss, NL; Kiryukhina, O; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L | 1 |
| Bolotokova, A; Devkota, K; Ghiabi, P; Hajian, T; Khalili Yazdi, A; Li, F; Loppnau, P; Perveen, S; Vedadi, M | 1 |
| Bolotokova, A; Devkota, K; Ghiabi, P; Hajian, T; Khalili Yazdi, A; Li, F; Perveen, S; Vedadi, M | 1 |
6 other study(ies) available for sinefungin and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.
Topics: Adenine; Betacoronavirus; Coronavirus Infections; COVID-19; Exoribonucleases; Humans; Methylation; Methyltransferases; Molecular Docking Simulation; Nucleosides; Pandemics; Pneumonia, Viral; RNA Caps; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Viral Nonstructural Proteins | 2020 |
Potent Inhibition of SARS-CoV-2 nsp14
Topics: COVID-19; COVID-19 Drug Treatment; Exoribonucleases; Humans; Methyltransferases; Molecular Docking Simulation; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Sulfonamides; Viral Nonstructural Proteins | 2022 |
Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin.
Topics: Adenosine; Betacoronavirus; Catalytic Domain; Coronavirus Infections; COVID-19; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Methyltransferases; Models, Chemical; Models, Molecular; Pandemics; Pneumonia, Viral; RNA Caps; RNA Stability; RNA, Viral; SARS-CoV-2; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins | 2020 |
High-resolution structures of the SARS-CoV-2 2'-
Topics: Adenosine; Betacoronavirus; Binding Sites; Catalytic Domain; Coronavirus Infections; COVID-19; Crystallography, X-Ray; Dimerization; Genes, Viral; Humans; Methylation; Methyltransferases; Models, Molecular; Open Reading Frames; Pandemics; Pneumonia, Viral; Protein Binding; Protein Conformation; RNA Cap Analogs; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; SARS-CoV-2; Structure-Activity Relationship; Viral Nonstructural Proteins | 2020 |
A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19.
Topics: Adenosine; Antiviral Agents; Binding, Competitive; COVID-19; COVID-19 Drug Treatment; Enzyme Inhibitors; Fluorescence Polarization; Gene Expression Regulation; High-Throughput Screening Assays; Host-Pathogen Interactions; Humans; Methyltransferases; Protein Binding; RNA Caps; RNA, Viral; SARS-CoV-2; Signal Transduction; Small Molecule Libraries; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins; Virus Replication | 2021 |
A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex.
Topics: Adenosine; Cloning, Molecular; COVID-19; Enzyme Assays; Enzyme Inhibitors; Escherichia coli; Gene Expression; Genetic Vectors; High-Throughput Screening Assays; Humans; Kinetics; Methylation; Methyltransferases; Models, Molecular; Recombinant Proteins; RNA Caps; RNA, Viral; SARS-CoV-2; Tritium; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins | 2021 |