sincalide has been researched along with Keratitis* in 1 studies
1 other study(ies) available for sincalide and Keratitis
Article | Year |
---|---|
Oxidized chondroitin sulfate eye drops ameliorate the prognosis of fungal keratitis with anti-inflammatory and antifungal effects.
Fungal keratitis (FK) is a refractory ophthalmic disease that can result in vision impairment and even blindness due to the severe fungal invasiveness and excessive inflammatory response. Therefore, antifungal treatment combined with local immunosuppressive therapy is regarded as the most effective strategy to improve the clinical outcome of FK. Oxidized polysaccharides with aldehyde groups possess obvious inhibitory activity towards microorganisms. Herein, we use chondroitin sulfate (CS), a recognized anti-inflammatory biopolysaccharide, to prepare oxidized chondroitin sulfate (OCS) Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Biocompatible Materials; Chondroitin Sulfates; Eye Infections, Fungal; Glucuronic Acid; Keratitis; Mice; Mice, Inbred C57BL; Ophthalmic Solutions; Prognosis; Sincalide | 2022 |